PEGylation Strategy for Improving the Pharmacokinetic and Antitumoral Activity of the IL-2 No-alpha Mutein.

Autor: Díaz-Hernández M; Department of Immune-regulation, Center of Molecular Immunology (Cuba), Havana, Cuba., Chang-Calderón J; Department of Immune-regulation, Center of Molecular Immunology (Cuba), Havana, Cuba., Álvarez MA; Department of Immune-regulation, Center of Molecular Immunology (Cuba), Havana, Cuba., Ramírez IR; Department of Quality Control, Center of Molecular Immunology (Cuba), Havana, Cuba., Saez OLF; Department of Product Development, Center of Molecular Immunology (Cuba), Havana, Cuba., Medinilla AL; Department of Rodent Facility, Center of Molecular Immunology (Cuba), Havana, Cuba., Castillo CYG; Department of Rodent Facility, Center of Molecular Immunology (Cuba), Havana, Cuba., Borges CD; Department of Immune-regulation, Center of Molecular Immunology (Cuba), Havana, Cuba., Chang SLL; Department of Product Development, Center of Molecular Immunology (Cuba), Havana, Cuba., León K; Department of Research, Development and Bussines Direction, Center of Molecular Immunology (Cuba), Havana, Cuba., Carmenate T; Department of Immune-regulation, Center of Molecular Immunology (Cuba), Havana, Cuba.

Publikováno v: Current pharmaceutical design [Curr Pharm Des] 2023; Vol. 29 (44), pp. 3579-3588.