Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Saet‐byel Jung"'
Autor:
Bo‐Kyoung Jung, Yong Hee An, Sung Hoon Jang, Gyoungah Ryu, Saet‐byel Jung, Seonhee Kim, Cuk‐Seong Kim, Hyun Jang
Publikováno v:
Cancer Medicine, Vol 12, Iss 20, Pp 20380-20395 (2023)
Abstract Background TRAIL is an anticancer drug that induces cancer cell apoptosis by interacting with death receptors (DRs). However, owing to low cell‐surface expression of DRs, certain colorectal cancer (CRC) cells resist TRAIL‐induced apoptos
Externí odkaz:
https://doaj.org/article/28d148d00a424ef3bcbd183e7b7ec3e4
Autor:
Ju Hee Lee, Saet-Byel Jung, Seong Eun Lee, Ji Eun Kim, Jung Tae Kim, Yea Eun Kang, Seul Gi Kang, Hyon-Seung Yi, Young Bok Ko, Ki Hwan Lee, Bon Jeong Ku, Minho Shong, Hyun Jin Kim
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 3, Pp 661-671 (2021)
Background The nature and role of the mitochondrial stress response in adipose tissue in relation to obesity are not yet known. To determine whether the mitochondrial unfolded protein response (UPRmt) in adipose tissue is associated with obesity in h
Externí odkaz:
https://doaj.org/article/c5997c190c6c4b05bed758f44c497228
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 1, Pp 1-11 (2021)
Paracrine interactions are imperative for the maintenance of adipose tissue intercellular homeostasis, and intracellular organelle dysfunction results in local and systemic alterations in metabolic homeostasis. It is currently accepted that mitochond
Externí odkaz:
https://doaj.org/article/c124a7b98ac642fab4ad6ac11a78104f
Autor:
Seul Gi Kang, Min Jeong Choi, Saet-Byel Jung, Hyo Kyun Chung, Joon Young Chang, Jung Tae Kim, Yea Eun Kang, Ju Hee Lee, Hyun Jung Hong, Sang Mi Jun, Hyun-Joo Ro, Jae Myoung Suh, Hail Kim, Johan Auwerx, Hyon-Seung Yi, Minho Shong
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102181- (2021)
Summary: Perturbation of mitochondrial proteostasis provokes cell autonomous and cell non-autonomous responses that contribute to homeostatic adaptation. Here, we demonstrate distinct metabolic effects of hepatic metabokines as cell non-autonomous fa
Externí odkaz:
https://doaj.org/article/61fd91c3505d466992b3cc6e208ce269
Autor:
Saet-Byel Jung, Min Jeong Choi, Dongryeol Ryu, Hyon-Seung Yi, Seong Eun Lee, Joon Young Chang, Hyo Kyun Chung, Yong Kyung Kim, Seul Gi Kang, Ju Hee Lee, Koon Soon Kim, Hyun Jin Kim, Cuk-Seong Kim, Chul-Ho Lee, Robert W. Williams, Hail Kim, Heung Kyu Lee, Johan Auwerx, Minho Shong
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
M1-like polarization of macrophages is thought to control adipose inflammation and associated insulin resistance and metabolic syndrome. Here the authors show that macrophage-specific deletion of the OxPhos-related gene Crif1 results in an M1-like ph
Externí odkaz:
https://doaj.org/article/e543088fca854de18576144178eee3f2
Rg3-enriched Korean Red Ginseng enhances blood pressure stability in spontaneously hypertensive rats
Publikováno v:
Integrative Medicine Research, Vol 5, Iss 3, Pp 223-229 (2016)
Background: Korean Red Ginseng (Panax ginseng) has been shown to exert antihypertensive effects. In particular, ginsenoside Rg3 is thought to be a potent modulator of vascular function. The present study was performed to examine the antihypertensive
Externí odkaz:
https://doaj.org/article/f2db37d13b2149df8e42c6d4dc1e601f
Autor:
Shuyu Piao, Jun Wan Lee, Harsha Nagar, Saet-Byel Jung, Sujeong Choi, Seonhee Kim, Ikjun Lee, Sung-Min Kim, Nara Shin, Yu Ran Lee, Sang Do Lee, Jin Bong Park, Kaikobad Irani, Minho Won, Gang Min Hur, Byeong Hwa Jeon, Dong Woon Kim, Cuk-Seong Kim
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192693 (2018)
CR6 interacting factor 1 (CRIF1) deficiency impairs mitochondrial oxidative phosphorylation complexes, contributing to increased mitochondrial and cellular reactive oxygen species (ROS) production. CRIF1 downregulation has also been revealed to decre
Externí odkaz:
https://doaj.org/article/866a0c21e02342b19c472e10cfd46719
Autor:
Jung-Bum Park, Sun Kwan Kwon, Harsha Nagar, Saet-byel Jung, Byeong Hwa Jeon, Chang Sup Kim, Jin-Hwan Oh, Hee-Jung Song, Cuk-Seong Kim
Publikováno v:
Journal of Ginseng Research, Vol 38, Iss 4, Pp 244-250 (2014)
Background: Panax ginseng has distinct and impressive health benefits, such as improved blood pressure and immune system functioning. Rg3-enriched Korean Red Ginseng (REKRG) isolated from Korean Red Ginseng contains a high percentage of Rg3. Methods:
Externí odkaz:
https://doaj.org/article/c2c3263e0e0b41c0bcdab107bef6b8fc
Autor:
Harsha Nagar, Saet-byel Jung, Sun Kwan Kwon, Jung-Bum Park, Minho Shong, Hee-Jung Song, Byeong Hwa Jeon, Kaikobad Irani, Cuk-Seong Kim
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98670 (2014)
Mitochondrial dysfunction has been implicated in the pathophysiology of various cardiovascular diseases. CRIF1 is a protein present in the mitochondria associated with large mitoribosomal subunits, and CRIF1 knockdown induces mitochondrial dysfunctio
Externí odkaz:
https://doaj.org/article/717730ee66f7401891b6d924003fbfbb
Autor:
Saet-Byel Jung, Cuk-Seong Kim, Young-Rae Kim, Asma Naqvi, Tohru Yamamori, Santosh Kumar, Ajay Kumar, Kaikobad Irani
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65415 (2013)
Apurinic/Apyrmidinic Endonuclease 1/Redox Factor-1 (APE1/Ref-1) is a reductant which is important for vascular homeostasis. SIRTUIN1 (SIRT1) is a lysine deacetylase that also promotes endothelium-dependent vasorelaxation. We asked if APE1/Ref-1 gover
Externí odkaz:
https://doaj.org/article/4b51e05f28ae4b94a996155009c03bcb