Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Saeko Moriuchi"'
Autor:
Hideaki Kaneto, Atsushi Obata, Masashi Shimoda, Tomohiko Kimura, Yoshiyuki Obata, Tomoko Ikeda, Saeko Moriuchi, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku
Publikováno v:
Journal of Diabetes Research, Vol 2023 (2023)
It has been shown that chronic hyperglycemia gradually decreases insulin biosynthesis and secretion which is accompanied by reduced expression of very important insulin gene transcription factors MafA and PDX-1. Such phenomena are well known as β-ce
Externí odkaz:
https://doaj.org/article/d9ea4ecc496146a3aa241124aae3bc63
Autor:
Kenji Kohara, Tomohiko Kimura, Atsushi Obata, Shuhei Nakanishi, Saeko Moriuchi, Hideaki Kaneto, Tomoatsu Mune, Hidenori Hirukawa, Yukiko Kanda-Kimura, Yuka Nogami, Masashi Shimoda, Kohei Kaku, Seizo Okauchi
Publikováno v:
Diabetes, Obesity and Metabolism. 20:2442-2457
Aims We compared the protective effects of sodium glucose co-transporter (SGLT) 2 inhibitor luseogliflozin on pancreatic β-cells between early and advanced stages of diabetes and between short- and long-term use. Materials and methods Diabetic db/db
Autor:
Hideaki Kaneto, Hidenori Hirukawa, Tomohiko Kimura, Kenji Kohara, Tomoatsu Mune, Kohei Kaku, Seizo Okauchi, Masashi Shimoda, Saeko Moriuchi, Atsushi Obata
Publikováno v:
Endocrine journal. 66(1)
It is known that long-chain fatty acids bind to free fatty acid receptor 1 (Ffar1), also known as G protein-coupled receptor 40 (GPR40), and amplify glucose-stimulated insulin secretion (GSIS) from pancreatic β-cells and that Ffar1 agonists facilita
Autor:
Kenji Kohara, Tomohiko Kimura, Hidenori Yoshitaka, Atsushi Obata, Genta Chikazawa, Kentaro Tamura, Arudo Hiraoka, Guy A. Rutter, Saeko Moriuchi, Hideaki Kaneto, Gabriela da Silva Xavier, Hidenori Hirukawa, Atsuhisa Ishida, Tomoatsu Mune, Kohei Kaku, Seizo Okauchi, Ikki Shimizu, Masashi Shimoda
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
It has been thought that incretin signaling prevents arteriosclerosis, and very recently anti-arteriosclerotic effects through GLP-1 receptor were finally demonstrated in clinical human study. The purpose of this study was to investigate how vascular
Autor:
Kenji Kohara, Atsushi Obata, Tomohiko Kimura, Masashi Shimoda, Saeko Moriuchi, Seizo Okauchi, Hidenori Hirukawa, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Publikováno v:
Endocrine Journal; 2019, Vol. 66 Issue 1, p43-50, 8p