Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Saeko Kuwahara‐Ota"'
Autor:
Yayoi Matsumura‐Kimoto, Taku Tsukamoto, Yuji Shimura, Yoshiaki Chinen, Kazuna Tanba, Saeko Kuwahara‐Ota, Yuto Fujibayashi, Daichi Nishiyama, Reiko Isa, Junko Yamaguchi, Yuka Kawaji‐Kanayama, Tsutomu Kobayashi, Shigeo Horiike, Masafumi Taniwaki, Junya Kuroda
Publikováno v:
Cancer Medicine, Vol 9, Iss 14, Pp 5185-5199 (2020)
Abstract RSK2 is a serine/threonine kinase downstream signaling mediator in the RAS/ERK signaling pathway and may be a therapeutic target in mantle cell lymphoma (MCL), an almost incurable disease subtype of non‐Hodgkin lymphoma. In this study, ser
Externí odkaz:
https://doaj.org/article/9e1e7146637b4917811ff4b9c406b974
Autor:
Yoshimi Mizuno, Taku Tsukamoto, Eri Kawata, Nobuhiko Uoshima, Hitoji Uchiyama, Isao Yokota, Saori Maegawa, Tomoko Takimoto, Kazuna Tanba, Yayoi Matsumura‐Kimoto, Saeko Kuwahara‐Ota, Yuto Fujibayashi, Mio Yamamoto‐Sugitani, Yoshiaki Chinen, Yuji Shimura, Shigeo Horiike, Masafumi Taniwaki, Tsutomu Kobayashi, Junya Kuroda
Publikováno v:
Cancer Medicine, Vol 7, Iss 3, Pp 655-664 (2018)
Abstract Diffuse large B‐cell lymphoma (DLBCL), which is the most prevalent disease subtype of non‐Hodgkin lymphoma, is highly heterogeneous in terms of cytogenetic and molecular features. This study retrospectively investigated the clinical impa
Externí odkaz:
https://doaj.org/article/5970ece3c6544cbb98a7014cb94e5845
Autor:
Junko Yamaguchi, Takahiro Fujino, Reiko Isa, Daichi Nishiyama, Saeko Kuwahara-Ota, Yuka Kawaji, Taku Tsukamoto, Yoshiaki Chinen, Yuji Shimura, Tsutomu Kobayashi, Shigeo Horiike, Kei Kohno, Shigeo Nakamura, Junya Kuroda
Publikováno v:
Haematologica, Vol 104, Iss 8 (2019)
Externí odkaz:
https://doaj.org/article/65fc80779c1d4266a977513eb1b533d7
Autor:
Kentaro Mizuhara, Yuji Shimura, Taku Tsukamoto, Akinori Kanai, Saeko Kuwahara-Ota, Junko Yamaguchi, Ayako Muramatsu, Haruya Okamoto, Yoko Katsuragawa-Taminishi, Yuka Kawaji-Kanayama, Reiko Isa, Shinsuke Mizutani, Toshiya Inaba, Junya Kuroda
Publikováno v:
Blood. 140:9949-9950
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dedf8f00aef3cf101e63a6c777958353
https://doi.org/10.1182/blood-2022-160408
https://doi.org/10.1182/blood-2022-160408
Autor:
Yoshiaki Chinen, Junya Kuroda, Yuto Fujibayashi, Tsutomu Kobayashi, Reiko Isa, Daichi Nishiyama, Shigeo Horiike, Yayoi Matsumura-Kimoto, Yuji Shimura, Junko Yamaguchi, Taku Tsukamoto, Saeko Kuwahara-Ota, Yuka Kawaji-Kanayama, Masafumi Taniwaki, Kazuna Tanba
Publikováno v:
Cancer Medicine, Vol 9, Iss 14, Pp 5185-5199 (2020)
Cancer Medicine
Cancer Medicine
RSK2 is a serine/threonine kinase downstream signaling mediator in the RAS/ERK signaling pathway and may be a therapeutic target in mantle cell lymphoma (MCL), an almost incurable disease subtype of non‐Hodgkin lymphoma. In this study, serine‐227
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578999d582d97bce168e4391b604b01e
https://doaj.org/article/9e1e7146637b4917811ff4b9c406b974
https://doaj.org/article/9e1e7146637b4917811ff4b9c406b974
Autor:
Shigeo Horiike, Yayoi Matsumura-Kimoto, Junya Kuroda, Taku Tsukamoto, Saeko Kuwahara-Ota, Tomoko Takimoto-Shimomura, Junko Yamaguchi, Reiko Isa, Yuji Shimura, Daichi Nishiyama, Christian Steinebach, Michael Gütschow, Masafumi Taniwaki, Tsutomu Kobayashi, Yoshimi Mizuno, Yoshiaki Chinen, Yuto Fujibayashi
Publikováno v:
British Journal of Haematology. 191:784-795
An increase in immunosuppressive myeloid-derived suppressor cells (MDSCs) is associated with disease progression and treatment resistance in multiple myeloma (MM). We investigated the mechanisms underlying MDSC induction, and sought to discover a str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf6cbcf98677ea7ebef3eccc80ccb9a
https://doi.org/10.1111/bjh.16881
https://doi.org/10.1111/bjh.16881
Autor:
Yoshiaki Chinen, Yuji Shimura, Tsutomu Kobayashi, Emiko Sakiyama, Tomoko Takimoto-Shimomura, Yayoi Matsumura-Kimoto, Taku Tsukamoto, Saeko Kuwahara-Ota, Shigeo Horiike, Junya Kuroda
Publikováno v:
Infection and Drug Resistance. 13:1017-1021
Ruxolitinib is a selective JAK1/2 inhibitor that is widely used for the treatment of myeloproliferative neoplasms (MPNs), including myelofibrosis and polycythemia vera (PV). Despite its clinical efficacy for MPNs, ruxolitinib possesses immunosuppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33321f41a41bb54f3bc9ddb23e2a6140
https://doi.org/10.2147/idr.s249030
https://doi.org/10.2147/idr.s249030
Autor:
Junya Kuroda, Junko Yamaguchi, Daichi Nishiyama, Tsutomu Kobayashi, Shigeo Horiike, Yuji Shimura, Reiko Isa, Tomoko Takimoto-Shimomura, Yoshiaki Chinen, Yuto Fujibayashi, Hiroshi Handa, Taku Tsukamoto, Saeko Kuwahara-Ota, Yayoi Matsumura-Kimoto, Masafumi Taniwaki
Publikováno v:
International journal of hematology. 113(3)
Multiple myeloma (MM) is cytogenetically, genetically and molecularly heterogenous even among subclones in one patient, therefore, it is essential to identify both frequent and patient-specific drivers of molecular abnormality. Following previous mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ae884053f182aa1707e71305cae086
https://pubmed.ncbi.nlm.nih.gov/33095415
https://pubmed.ncbi.nlm.nih.gov/33095415
Autor:
Masakazu Nakano, Yoshiaki Chinen, Shingo Nakahata, Junya Kuroda, Kei Tashiro, Tomoko Takimoto-Shimomura, Toshiya Inaba, Ryuichi Sato, Akinori Kanai, Yoshimi Mizuno, Yuka Kawaji, Yayoi Matsumura-Kimoto, Taku Tsukamoto, Saeko Kuwahara-Ota, Saori Maegawa-Matsui, Kazuhiro Morishita, Masafumi Taniwaki
Background Since bromodomain-containing protein 4 (BRD4) facilitates the transcription of genes important for neoplastic cells in a cancer-type specific manner, BRD4-regulated molecules may also include therapeutic targets for mantle cell lymphoma (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7569396823cf2bc0f2a2d732c13253b
https://europepmc.org/articles/PMC6937128/
https://europepmc.org/articles/PMC6937128/
Autor:
Yuji Shimura, Kazuna Tanba, Yayoi Matsumura-Kimoto, Yoshiaki Chinen, Yoshimi Mizuno, Tsutomu Kobayashi, Taku Tsukamoto, Saeko Kuwahara-Ota, Shigeo Horiike, Junya Kuroda, Shinsuke Mizutani, Tomoko Takimoto-Shimomura
Publikováno v:
Infection and Drug Resistance
Primary infection with human herpesvirus-6 (HHV-6) commonly occurs at an early age in children, most often at 3 years of age, and is associated with childhood diseases, such as exanthema subitum, hepatitis, febrile convulsions, or encephalitis. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe37ce2a16d7bbb825f690ea0cdae476
https://doi.org/10.2147/idr.s163686
https://doi.org/10.2147/idr.s163686