Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Saejeong Park"'
Autor:
Saejeong Park, Zhiyuan Ma, Georgia Zarkada, Irinna Papangeli, Sarin Paluri, Nour Nazo, Felix Rivera‐Molina, Derek Toomre, Sudarshan Rajagopal, Hyung J. Chun
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Modulation of endothelial cell behavior and phenotype by hemodynamic forces involves many signaling components, including cell surface receptors, intracellular signaling intermediaries, transcription factors, and epigenetic elements. Many of
Externí odkaz:
https://doaj.org/article/fb5e7074c9564817987662362c67b496
Autor:
Irinna Papangeli, Jongmin Kim, Inna Maier, Saejeong Park, Aram Lee, Yujung Kang, Keiichiro Tanaka, Omar F. Khan, Hyekyung Ju, Yoko Kojima, Kristy Red-Horse, Daniel G. Anderson, Arndt F. Siekmann, Hyung J. Chun
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
G protein-coupled receptors APLNR and CXCR4 are crucial for vascular development. Here, the authors show that these two signaling pathways communicate and that in response to blood flow APLNR signaling induces a decrease in CXCR4 expression via miR-1
Externí odkaz:
https://doaj.org/article/f8d99b3209af438b97ff65e526d3b632
Autor:
Heon-Woo Lee, Takaomi Adachi, Boryeong Pak, Saejeong Park, Xiaoyue Hu, Woosoung Choi, Piotr S Kowalski, C Hong Chang, Katharine R Clapham, Aram Lee, Irinna Papangeli, Jongmin Kim, Orjin Han, Jihwan Park, Daniel G Anderson, Michael Simons, Suk-Won Jin, Hyung J Chun
Publikováno v:
Cardiovascular research.
Aims Components of bone morphogenetic protein (BMP) signalling have been implicated in both pathogenesis of pulmonary arterial hypertension (PAH) and endothelial-mesenchymal transition (EndoMT). In particular, the importance of BMP type 2 receptor in
Autor:
Saejeong Park, Takaomi Adachi, Suk-Won Jin, Daniel G. Anderson, Heon-Woo Lee, Michael Simons, Piotr S. Kowalski, Hyung J. Chun
Publikováno v:
Circulation. 138
There is emerging evidence that the aberrant pulmonary vascular remodeling that occurs in pulmonary arterial hypertension (PAH) is at least in part driven by the transformation of endothelial cells to mesenchymal cells (EndoMT), but the mechanism dri
Autor:
Hyekyung Ju, Omar F. Khan, Yujung Kang, Arndt F. Siekmann, Aram Lee, Saejeong Park, Irinna Papangeli, Keiichiro Tanaka, Hyung J. Chun, Inna Maier, Kristy Red-Horse, Daniel G. Anderson, Jongmin Kim, Yoko Kojima
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Publishing Group
Nature Communications
Nature Publishing Group
G protein-coupled receptor (GPCR) signalling, including that involving apelin (APLN) and its receptor APLNR, is known to be important in vascular development. How this ligand–receptor pair regulates the downstream signalling cascades in this contex
Autor:
Ming O. Li, Takaomi Adachi, Thomas Quertermous, Guoliang Cui, Hyekyung Ju, Alan R. Morrison, Gwang-woong Go, Lina Zhao, Kristy Red-Horse, Mohammed Inayathullah, Bikram Sharma, Jayakumar Rajadas, Stephanie L. Kwei, Judith K. Job, Hyung J. Chun, Jingxia Wu, Arya Mani, Cheol Hwangbo, Irinna Papangeli, Saejeong Park
Publikováno v:
Science Translational Medicine. 9
Treatment of type 2 diabetes mellitus continues to pose an important clinical challenge, with most existing therapies lacking demonstrable ability to improve cardiovascular outcomes. The atheroprotective peptide apelin (APLN) enhances glucose utiliza
Autor:
Cheol Hwangbo, Jingxia Wu, Papangeli, Irinna, Adachi, Takaomi, Sharma, Bikram, Saejeong Park, Lina Zhao, Hyekyung Ju, Gwang-woong Go, Guoliang Cui, Inayathullah, Mohammed, Job, Judith K., Rajadas, Jayakumar, Kwei, Stephanie L., Li, Ming O., Morrison, Alan R., Quertermous, Thomas, Mani, Arya, Red-Horse, Kristy, Chun, Hyung J.
Publikováno v:
Science Translational Medicine; 9/13/2017, Vol. 9 Issue 407, p1-14, 14p