Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Saeed Solali"'
Autor:
Mehdi Sajjadi-Dokht, Talar Ahmad Merza Mohamad, Heshu Sulaiman Rahman, Marwah Suliman Maashi, Svetlana Danshina, Navid Shomali, Saeed Solali, Faroogh Marofi, Elham Zeinalzadeh, Morteza Akbari, Ali Adili, Ramin Aslaminabad, Majid Farshdousti Hagh, Mostafa Jarahian
Publikováno v:
Genes and Diseases, Vol 9, Iss 4, Pp 849-867 (2022)
Blood disorders include a wide spectrum of blood-associated malignancies resulting from inherited or acquired defects. The ineffectiveness of existing therapies against blood disorders arises from different reasons, one of which is drug resistance, s
Externí odkaz:
https://doaj.org/article/2c8220d985c64320a032d4464b04d3f2
Autor:
Sahar Safaei, Behzad Baradaran, Behzad Mansoori, Masoumeh Fardi, Elham Baghbani, Mohammad Amini, Nima Hemmat, Elham Safarzadeh, Mahdi Abdoli Shadbad, Dariush Shanehbandi, Saeed Solali
Publikováno v:
Pharmaceutical Sciences, Vol 28, Iss 3, Pp 394-404 (2022)
Background: EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), as one of the polycyclic group proteins (PcGs), is an epigenetic regulator that plays a crucial role in the pathophysiology of hematologic malignancies through regulating c
Externí odkaz:
https://doaj.org/article/18eec43eba4146b0b2ffecd1005c5145
Autor:
Elham Zeinalzadeh, Alexey Valerievich Yumashev, Heshu Sulaiman Rahman, Faroogh Marofi, Navid Shomali, Hossein Samadi Kafil, Saeed Solali, Mehdi Sajjadi-Dokht, Sajjad Vakili-Samiani, Mostafa Jarahian, Majid Farshdousti Hagh
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway has been known to be involved in cell growth, cellular differentiation processes development, immune cell survival, and hematopoietic system development.
Externí odkaz:
https://doaj.org/article/cf3ed0f7de0147d793a0efc4b015cd3f
Autor:
Kobra Shojaei Moghadam, Majid Farshdousti Hagh, Mohammad Reza Alivand, Masoumeh Fardi, Ali Akbar Movassaghpour, Ali Mohammadi, Maryam Moghadasi, Saeed Solali
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 10, Iss 1, Pp 81-87 (2020)
Purpose: Sepantronium bromide (YM155) is a Survivin inhibitor which recently advanced as an anticancer agent in phase II clinical trials. Survivin belongs to IAP (inhibitor of apoptosis) gene family and is a pivotal target for treatment due to its ov
Externí odkaz:
https://doaj.org/article/d84557918c9a4b27a36f02d3c50ce960
Publikováno v:
Genes and Diseases, Vol 5, Iss 4, Pp 304-311 (2018)
Epigenetic, along with genetic mechanisms, is essential for natural evolution and maintenance of specific patterns of gene expression in mammalians. Global epigenetic variation is inherited somatically and unlike genetic variation, it is dynamic and
Externí odkaz:
https://doaj.org/article/42e0aa0e7d4f4a65ac4e6f41d238390b
Publikováno v:
Basic & Clinical Cancer Research, Vol 12, Iss 2 (2020)
Background: This study evaluated and compared the quantitative expression of Multidrug Resistance-associated Protein 1 (MRP1) and ATP Binding Cassette subfamily G member 2 ( ABCG2), two Multidrug Resistance (MDR) related genes, in 30 CML patients and
Externí odkaz:
https://doaj.org/article/b2198f23f6594858938e982a7bfb7a12
Autor:
Milad Ahani-Nahayati, Saeed Solali, Karim Shams Asenjan, Ali Akbar Movassaghpour Akbari, Mehdi Talebi, Milad Zadi Heydarabad, Sina Baharaghdam, Majid Farshdousti Hagh
Publikováno v:
Cell Journal, Vol 20, Iss 2, Pp 188-194 (2018)
Objective DNA methylation is a well-studied epigenetic mechanism that is a potent arm of the gene expression controlling machinery. Since the hypoxic situation and the various cells of bone marrow microenvironment, e.g. mesenchymal stem cells, play
Externí odkaz:
https://doaj.org/article/2c819c9a1a0942f08bd5c60a9bd61fae
Autor:
Masoud Soleimani, Mohammad Asghari-Jafarabadi, Heshu Sulaiman Rahman, Adel Naimi, Raedeh Saraei, Saeed Solali, Ali Hassanzadeh
Publikováno v:
Molecular Biology Reports. 49:19-29
The tumor necrosis factor (TNF)-related apoptosis-inducing ligand, TRAIL, an apoptosis-inducing cytokine, has attracted much attention in the treatment of cancer for its selective toxicity to malignant rather than normal cells. However, the apoptosis
Autor:
Fatemeh Najafi, Shohre Karimi Kelaye, Bahareh Kazemi, Zahra Foruzandeh, Farahnaz Allahverdizadeh, Sajjad Vakili, Kowsar Kiani Rad, Mahdi Derakhshani, Saeed Solali, Mohammad Reza Alivand
Publikováno v:
Pathology, research and practice. 239
However, advanced technologies have been developed in the treatment of various cancers, but the mortality rate from cancer is still very high. Drug resistance is a major problem for patients with cancer, which causes the treatment process to fail. In
Autor:
Fatemeh Najafi, Shohre Karimi Kelaye, Bahareh Kazemi, Zahra Foruzandeh, Farahnaz Allahverdizadeh, Sajjad Vakili, Farhad Seif, Mahdi Derakhshani, Saeed Solali, Mohammad Reza Alivand
Background However, advanced technologies have been developed in the treatment of various cancers, but the mortality rate from cancer is still very high. Drug resistance is a major problem for patients with cancer, which causes the treatment process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f610a76448f9d4568c2f090e4bc7ad7
https://doi.org/10.21203/rs.3.rs-1108254/v2
https://doi.org/10.21203/rs.3.rs-1108254/v2