Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saeed Pourmand"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Glycogen synthase kinase 3-beta (GSK3-β) is a serine-threonine protease expressed in the brain, and its hyperactivity is considered the underlying cause of Alzheimer’s disease. This enzyme requires an ATP molecule in its N-terminal lobe t
Externí odkaz:
https://doaj.org/article/3076d1b4f03a462396be9199346a3376
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The SARS-CoV-2, the virus which is responsible for COVID-19 disease, employs its spike protein to recognize its receptor, angiotensin-converting enzyme 2 (ACE2), and subsequently enters the host cell. In this process, the receptor-binding domain (RBD
Externí odkaz:
https://doaj.org/article/372317a6252c47b682b4cf2a6394b3e4
Autor:
Marzieh Eskandarzadeh, Parastou Kordestani-Moghadam, Saeed Pourmand, Javad Khalili Fard, Bijan Almassian, Sajjad Gharaghani
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The inhibition of glycogen synthase kinase-3β (GSK-3β) activity prevents tau hyperphosphorylation and binds it to the microtubule network. Therefore, a GSK-3β inhibitor may be a recommended drug for Alzheimer’s treatment. In silico methods are c
Externí odkaz:
https://doaj.org/article/767a747bf18a492ea7aea37d26061854
Publikováno v:
Chemical Papers. 77:1129-1148
The current viral pandemic, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), creates health, mental, economic, and other serious challenges that are better to say global crisis. Despite the
Publikováno v:
Chemical Papers.
Publikováno v:
Natural Product Research. 36:4254-4260
This research investigates antiviral potential of extracted honeybee products against COVID-19 main protease (Mpro) by computational methods. The crystal structure of COVID-19 Mpro was obtained from the protein data bank. Six synthetic drugs with ant
Publikováno v:
Computers in biology and medicine. 146
The outbreak of COVID-19 has resulted in millions of deaths. Despite all attempts that have been made to combat the pandemic, the re-emergence of new variants complicated SARS-CoV-2 eradication. The ongoing global spread of COVID-19 demands the inces
Publikováno v:
Journal of Molecular Liquids. 338:117114
Natural gas sweetening is one of the important processes in petroleum industry. Ionic liquids (ILs) as a new class of compounds are an alternative to conventional solvents to achieve this goal. In this study, the solubility of H2S gas in ionic liquid