Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Saeed Balalaie"'
Publikováno v:
Frontiers in Biomaterials Science, Vol 3 (2024)
The development of safe and efficient delivery systems for targeted and controlled release of therapeutic agents has become a major focus in pharmacotherapy. The colon is one organ that serves as an optimal site for the absorption of protein and pept
Externí odkaz:
https://doaj.org/article/a6ae3f25019f4387bc56460826536874
Autor:
Fatemeh Ebrahimi, Nooshin Reisi Zargari, Mehdi Akhlaghi, S. Mohsen Asghari, Khosrou Abdi, Saeed Balalaie, Mahboobeh Asadi, Davood Beiki
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 899 (2024)
As angiogenesis plays a pivotal role in tumor progression and metastasis, leading to more cancer-related deaths, the angiogenic process can be considered as a target for diagnostic and therapeutic applications. The vascular endothelial growth factor
Externí odkaz:
https://doaj.org/article/b4ff7145cd7d46748cd8174ce6863dbe
Autor:
Hanieh Rabouti, S. Mohsen Asghari, Reihaneh Sariri, Saeed Balalaie, AbdolMajid Valipour, Navid Omidian, Behrooz Heidari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Kisspeptin (kp) is a key regulator of reproduction, which stimulates sexual maturation and gametogenesis in mammals, amphibians, and teleosts. In the present study, to enhance the biological activity of kp10, a novel analog (referred to as M
Externí odkaz:
https://doaj.org/article/7a38e90387634c96a3077b987cf03a60
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract This manuscript reports an impressive and facile strategy for synthesizing isoxazole derivatives using immobilized Cu (I) in metformin-functionalized β-cyclodextrin as a catalyst. The architecture of this catalyst was characterized by diffe
Externí odkaz:
https://doaj.org/article/a4dd1e86f2ad4ddf932be476b71f5f4a
Autor:
Mojtaba Ayoubi, Ali Nikbakht, Kamran Amiri, Alireza Abbasi Kejani, Hossein Zahedian Tejeneki, Saeed Balalaie
Publikováno v:
SynOpen, Vol 06, Iss 01, Pp 11-15 (2022)
We describe a novel, simple, robust, and efficient cyclization/deoxygenation approach for the synthesis of functionalized isoquinoline derivatives. Over the course of continued studies on o-alkynylbenzaldoxime cyclization reactions, the formation of
Externí odkaz:
https://doaj.org/article/8f268ce6efdc4c5b8ea9a6fa8a754c8a
Autor:
Mohadeseh Namjoo, Hossein Ghafouri, Elham Assareh, Amir Reza Aref, Ebrahim Mostafavi, Ali Hamrahi Mohsen, Saeed Balalaie, Sylvain Broussy, S. Mohsen Asghari
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 906 (2023)
Vascular endothelial growth factor receptor 2 (VEGFR2) mediates VEGFA signaling mainly through the PI3K/AKT/mTOR and PLCγ/ERK1/2 pathways. Here we unveil a peptidomimetic (VGB3) based on the interaction between VEGFB and VEGFR1 that unexpectedly bin
Externí odkaz:
https://doaj.org/article/4ea326966c134fe6a151e0b74947abf2
Publikováno v:
Catalysts, Vol 13, Iss 1, p 87 (2023)
Ruthenium complexes are remarkable catalysts for the C–H activation approaches and organic transformations. Combining a Ru-catalyst with oxidants and other additives in a one-pot process is considered a sustainable approach due to the reduction in
Externí odkaz:
https://doaj.org/article/bead92dea3074d318d28fa3ec3eb35e8
Autor:
Alexander Sapegin, Elizaveta Rogacheva, Lyudmila Kraeva, Maxim Gureev, Marine Dogonadze, Tatiana Vinogradova, Petr Yablonsky, Saeed Balalaie, Sergey V. Baykov, Mikhail Krasavin
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2203 (2022)
A chemically diverse set of 13 5-nitrofuran-tagged heterocyclic compounds has been prepared via the Groebke–Blackburn–Bienaymé multicomponent reaction. The testing of these compounds against the so-called ESKAPE panel of pathogens identified an
Externí odkaz:
https://doaj.org/article/90fee82d671e46acb6dca5a868f2b615
Autor:
Razieh Navari, Saeed Balalaie, Saber Mehrparvar, Fatemeh Darvish, Frank Rominger, Fatima Hamdan, Sattar Mirzaie
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 874-880 (2019)
An efficient approach for the synthesis of pyrazolopyridines containing the aminochromane motif through a base-catalyzed cyclization reaction is reported. The synthesis was carried out through a three-component reaction of (arylhydrazono)methyl-4H-ch
Externí odkaz:
https://doaj.org/article/cbc4d5327e064af28bab10ca4ba3a74d
Autor:
Saeed Balalaie, Hadiseh Bakhshaei Ghoroghaghaei, Nahid S. Alavijeh, Fatemeh Darvish, Frank Rominger, Hamid Reza Bijanzadeh
Publikováno v:
SynOpen, Vol 02, Iss 03, Pp 0222-0228 (2018)
Abstract Biologically attractive azaspiro[4.5]trienones have been prepared via Ugi four-component reaction (Ugi-4CR) followed by bromine-mediated ipso-cyclization. This allows a straightforward synthetic route to a diverse collection of fully functio
Externí odkaz:
https://doaj.org/article/870a8de476ae4a9c96e5a1b5c90f5bd4