Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Saeed, Shoaie"'
Autor:
Lingqi Meng, Han Jin, Burak Yulug, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Saeed Shoaie, Hasan Turkez, Jens Nielsen, Cheng Zhang, Jan Borén, Mathias Uhlén, Adil Mardinoglu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder with a global impact, yet its pathogenesis remains poorly understood. While age, metabolic abnormalities, and accumulation of neurotoxic substances are potential risk fa
Externí odkaz:
https://doaj.org/article/39a09c10d79c4cb7af897566df85c1bc
Autor:
Sunjae Lee, Victoria Meslier, Gholamreza Bidkhori, Fernando Garcia-Guevara, Lucie Etienne-Mesmin, Frederick Clasen, Junseok Park, Florian Plaza Oñate, Haizhuang Cai, Emmanuelle Le Chatelier, Nicolas Pons, Marcela Pereira, Maike Seifert, Fredrik Boulund, Lars Engstrand, Doheon Lee, Gordon Proctor, Adil Mardinoglu, Stéphanie Blanquet-Diot, David Moyes, Mathieu Almeida, S. Dusko Ehrlich, Mathias Uhlen, Saeed Shoaie
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Species composition of the healthy adult gut microbiota tends to be stable over time. Destabilization of the gut microbiome under the influence of different factors is the main driver of the microbial dysbiosis and subsequent impacts on host
Externí odkaz:
https://doaj.org/article/a887eb4803374d36b77690db31148648
Autor:
Torben Hansen, Pere Ginès, Wim Laleman, Peer Bork, Vishal C Patel, Debbie Shawcross, Robert Schierwagen, Camila Alvarez-Silva, Florence Servant, Jonel Trebicka, Benjamin Lelouvier, Manimozhiyan Arumugam, Ed J Kuijper, Frank Erhard Uschner, Michael Praktiknjo, Mária Papp, Saeed Shoaie, Michael Kühn, Maja Thiele, Paolo Angeli, Joan Claria, Vicente Arroyo, Manolo Laiola, Benoit Quinquis, Sabine Klein, Minneke J Coenraad, François Fenaille, Debbie Lindsay Shawcross, Wenyi Gu, Adria Juanola, Elisa Pose, Aleksander Krag, Ivica Letunic, Alain Pruvost, Hervé M Blottière, Nathalie Galleron, Cristina López-Vicario, Peter V Treit, Matthias Mann, Jelle Matthijnssens, Mark J W Mcphail, Philipp E Geyer, Hans Olav Melberg, Stefanie Kandels, Cristina Sánchez-Garrido, Florence A Castelli, Christophe Junot, Lars Asphaug, Mads Israelsen, Helene Bæk Juel, Nikolaj Torp, Minneke Coenraad, Marko Korenjak, Ferran Aguilar-Parera, Patricia Sierra-Casas, Anna Bosch-Comas, David Tornai, Boglarka Balogh, Katrine Holtz Thorhauge, Casper Sahl Poulsen, Thea Van Rossum, Suguru Nishijima, Marisa I Keller, Diënty H M Hazenbrink, Sylvain Dechaumet, Sebastian D Burz, Emeline Chu-Van, Etienne Thévenot, Florian A Rosenberger, Sebastian Van Blerk, Amirouche Ouzerdine, Alain Roulet, Jean-Louis-Marie Insonere, Céline Serres, Mathieu Almeida, Florence Thirion, Camille Champion, Chaima Ezzine, Célia Chamignon, Nicolas Lapaque, Mamadou Gabou Thiam, Lore Van Espen, Quinten R Ducarmon, Annelotte GC Broekhoven, Susan Fischer, Romy Zwittink, Itziar De Lecuona, Giulio Rosati, Celia Fuentes-Chust, Arben Merkoçi, Massimo Urban, José Alfonso Marrugo-Ramirez, Ameli Schwalber, Lindsey Ann Edwards, Victoria Tatiana Kronsten, David Moyes, Azadeh Harzandi, Jordi Gratacós-Ginès, Martina Pérez-Guasch, Miriam Pellón, Bryan Contreras, Max Brol, Manfred Fobker, Renata Antonina Feuerborn
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Human albumin is used in the treatment of complications of cirrhosis. However, the use of long-term human albumin administration is costly and resource demanding for both patients and healthcare systems. A precision medicine approach wit
Externí odkaz:
https://doaj.org/article/289f12a27d2047adb5cb758cb2809703
Autor:
Ali Kaynar, Mehmet Ozcan, Xiangyu Li, Hasan Turkez, Cheng Zhang, Mathias Uhlén, Saeed Shoaie, Adil Mardinoglu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7868 (2024)
Glioblastoma (GBM), a highly malignant tumour of the central nervous system, presents with a dire prognosis and low survival rates. The heterogeneous and recurrent nature of GBM renders current treatments relatively ineffective. In our study, we util
Externí odkaz:
https://doaj.org/article/1bc3a10cd2164edd80c9541d6296d434
Autor:
Abdulahad Bayraktar, Xiangyu Li, Woonghee Kim, Cheng Zhang, Hasan Turkez, Saeed Shoaie, Adil Mardinoglu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Despite numerous clinical trials and decades of endeavour, there is still no effective cure for Alzheimer's disease. Computational drug repositioning approaches may be employed for the development of new treatment strategies for A
Externí odkaz:
https://doaj.org/article/b643e1e632a14da1afd8a2e2dde59ac7
Autor:
Ozlem Altay, Hong Yang, Serkan Yildirim, Cemil Bayram, Ismail Bolat, Sena Oner, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Ahmet Hacimuftuoglu, Saeed Shoaie, Cheng Zhang, Jan Borén, Mathias Uhlén, Hasan Turkez, Adil Mardinoglu
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 927 (2024)
Background: Mitochondrial dysfunction and metabolic abnormalities are acknowledged as significant factors in the onset of neurodegenerative disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD). Our research has demonstrated tha
Externí odkaz:
https://doaj.org/article/82d23cf6ae5d4d6bb1de51ae8dca2f4e
Autor:
Gholamreza Bidkhori, Saeed Shoaie
Publikováno v:
Metabolites, Vol 14, Iss 3, p 132 (2024)
Understanding microbial metabolism is crucial for evaluating shifts in human host–microbiome interactions during periods of health and disease. However, the primary hurdle in the realm of constraint-based modeling and genome-scale metabolic models
Externí odkaz:
https://doaj.org/article/6938e2ecffde4ce9bacaa1ba244bbe90
Autor:
Burak Yulug, Ozlem Altay, Xiangyu Li, Lutfu Hanoglu, Seyda Cankaya, Simon Lam, Halil Aziz Velioglu, Hong Yang, Ebru Coskun, Ezgi Idil, Rahim Nogaylar, Ahmet Ozsimsek, Cemil Bayram, Ismail Bolat, Sena Oner, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Ahmet Hacimuftuoglu, Serkan Yildirim, Muhammad Arif, Saeed Shoaie, Cheng Zhang, Jens Nielsen, Hasan Turkez, Jan Borén, Mathias Uhlén, Adil Mardinoglu
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-23 (2023)
Abstract Background Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed that CMA improve
Externí odkaz:
https://doaj.org/article/278f5ef5f370458b8e4a1065e71e2ca4
Autor:
Bouchra Ezzamouri, Dorines Rosario, Gholamreza Bidkhori, Sunjae Lee, Mathias Uhlen, Saeed Shoaie
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract The human gut microbiome has been associated with several metabolic disorders including type 2 diabetes mellitus. Understanding metabolic changes in the gut microbiome is important to elucidate the role of gut bacteria in regulating host met
Externí odkaz:
https://doaj.org/article/89849651f01544f3b2f52806c5993f83
Autor:
Neelu Begum, Sunjae Lee, Theo John Portlock, Aize Pellon, Shervin Dokht Sadeghi Nasab, Jens Nielsen, Mathias Uhlen, David L. Moyes, Saeed Shoaie
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Metabolic differences between Candida species are uncovered using the BioFung database alongside genomic and metabolic analysis.
Externí odkaz:
https://doaj.org/article/ed773267446344fa9204e94dfdd48fed