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Quantification of left ventricular ejection fraction and cardiac output using a novel semi-automated echocardiographic method: a prospective observational study in coronary artery bypass patients

Autor: Thomas Komanek, Marco Rabis, Saed Omer, Jürgen Peters, Ulrich H. Frey

Publikováno v: BMC Anesthesiology, Vol 23, Iss 1, Pp 1-11 (2023)

Abstract Background Echocardiographic quantification of ejection fraction (EF) by manual endocardial tracing requires training, is time-consuming and potentially user-dependent, whereas determination of cardiac output by pulmonary artery catheterizat

Externí odkaz: https://doaj.org/article/35dd23260714411aa617c7277463bb8d

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Polymorphic Variants in the GRK5 Gene Promoter Are Associated With Diastolic Dysfunction in Coronary Artery Bypass Graft Surgery Patients

Autor: Philipp Fassbender, Stefanie Klenke, Saed Omer, Tomas Komanek, Crista Ochsenfarth, Ulrich H. Frey, Jürgen Peters

Publikováno v: Anesthesia & Analgesia. 134:858-868

The G-protein-coupled receptor kinase 5 (GRK5) is a mediator of cardiovascular homeostasis and participates in inflammation and cardiac fibrosis, both being involved in the development of diastolic dysfunction (DD). While mechanisms of transcriptiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91840956b0864793dd2366c9743e203
https://doi.org/10.1213/ane.0000000000005809

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