Zobrazeno 1 - 8
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pro vyhledávání: '"Sae-Hun Park"'
Publikováno v:
Cell. 171(4)
Eukaryotic cells have evolved extensive protein quality-control mechanisms to remove faulty translation products. Here, we show that yeast cells continually produce faulty mitochondrial polypeptides that stall on the ribosome during translation but a
Autor:
Philip Coffino, Frederik Eisele, Zlatka Kostova, Dieter H. Wolf, Natalia Bolender, Sae-Hun Park, Junko Takeuchi
Publikováno v:
Molecular Biology of the Cell. 18:153-165
The mechanism of protein quality control and elimination of misfolded proteins in the cytoplasm is poorly understood. We studied the involvement of cytoplasmic factors required for degradation of two endoplasmic reticulum (ER)-import-defective mutate
Autor:
Young-Jun Choe, Timm Hassemer, Lisa Vincenz-Donnelly, Sae-Hun Park, F. Ulrich Hartl, Manajit Hayer-Hartl, Roman Körner
Publikováno v:
Nature
Translation of messenger RNAs lacking a stop codon results in the addition of a carboxy-terminal poly-lysine tract to the nascent polypeptide, causing ribosome stalling. Non-stop proteins and other stalled nascent chains are recognized by the ribosom
Publikováno v:
The Journal of biological chemistry. 278(38)
The endoplasmic reticulum (ER) harbors a protein quality control system, which monitors protein folding in the ER. Elimination of malfolded proteins is an important function of this protein quality control. Earlier studies with various soluble and tr
Publikováno v:
Korean Journal of Anesthesiology. 44:201
Background: Potent inhalational agents are widely used for thoracic anesthesia. They have several desirable properties, including ease of administration, rapid onset and offset, and bronchodilation. One potential drawback is their ability to directly
Autor:
F. Ulrich Hartl, Yury Kukushkin, Sae-Hun Park, Ayano Konagai, Manajit Hayer-Hartl, Mark S. Hipp, Rajat Gupta, Taotao Chen
Publikováno v:
Cell. (1):134-145
SummaryDysfunction of protein quality control contributes to the cellular pathology of polyglutamine (polyQ) expansion diseases and other neurodegenerative disorders associated with aggregate deposition. Here we analyzed how polyQ aggregation interfe
Autor:
Sae Hun. Park
Publikováno v:
Underwater acoustic propagation in the Korea strait.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3928aa7050b453b73de91ce6b1a85d81
https://doi.org/10.5962/bhl.title.61938
https://doi.org/10.5962/bhl.title.61938
Autor:
Taxis, Christof1,2, Hitt, Reiner1, Sae-Hun Park, Reiner1, Deak, Peter M.1,3, Kostova, Zlatka1, Wolf, Dieter H.1 dieter.wolf@po.uni-stuttgart.de
Publikováno v:
Journal of Biological Chemistry. 9/19/2003, Vol. 278 Issue 38, p35903-35913. 11p. 3 Diagrams, 1 Chart, 12 Graphs.