Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sae Rin, Jean"'
Autor:
Libing Zhang, Sae Rin Jean, Sharif Ahmed, Peter M. Aldridge, Xiyan Li, Fengjia Fan, Edward H. Sargent, Shana O. Kelley
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The development of nanomaterials for imaging and drug delivery has been of great interest to the field. Here, the authors synthesized multifunctional enzyme-responsive hydrogels with self-assembling quantum dots for nucleic acid and drug delivery as
Externí odkaz:
https://doaj.org/article/a77206f541eb453abe74c5e400bf7a82
Autor:
Chiara Riganti, Massimo Serra, Shana O. Kelley, Silvia Deaglio, Claudia M. Hattinger, Eleonora Mungo, Ilaria Roato, Costanzo Costamagna, Iris C. Salaroglio, Marilù Fanelli, Joanna Kopecka, Valentina Audrito, Sae Rin Jean, Elena Gazzano, Ilaria Buondonno
Legends of Supplementary Figures S1-S7; Supplementary Tables S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e9bb342b6c7c5b58ade804563ca937
https://doi.org/10.1158/1535-7163.22505890.v1
https://doi.org/10.1158/1535-7163.22505890.v1
Autor:
Chiara Riganti, Massimo Serra, Shana O. Kelley, Silvia Deaglio, Claudia M. Hattinger, Eleonora Mungo, Ilaria Roato, Costanzo Costamagna, Iris C. Salaroglio, Marilù Fanelli, Joanna Kopecka, Valentina Audrito, Sae Rin Jean, Elena Gazzano, Ilaria Buondonno
Dose-response effects of mitochondria-targeted doxorubicin on drug-resistant osteosarcoma in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8540e6c25786b0bfb6e2de2187ef0332
https://doi.org/10.1158/1535-7163.22505896
https://doi.org/10.1158/1535-7163.22505896
Autor:
George S. Laszlo, Colin D. Godwin, Roland B. Walter, Eliotte E. Garling, Michael H. Cardone, Mary E. Beddoe, Sae Rin Jean, Olivia M. Bates
Publikováno v:
Leuk Lymphoma
Over 26,000 people will face a new diagnosis of acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) in 2020 in the U.S. alone, and only a minority will be long-term survivors [1]. Am...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b28ca7c38f74944f6eafe4f7f17514
https://doi.org/10.1080/10428194.2020.1786553
https://doi.org/10.1080/10428194.2020.1786553
Autor:
Ravi Vij, Mark A. Fiala, Mark A. Schroeder, Savina Jaeger, Keith Stockerl-Goldstein, Armin Ghobadi, Tanya M. Wildes, Kathryn Shea, Eric Huselton, Sae Rin Jean, Michael H. Cardone
Publikováno v:
Clin Cancer Res
Purpose: Pegylated liposomal doxorubicin (PLD) combined with bortezomib is an effective salvage regimen for relapsed refractory multiple myeloma (RRMM). Carfilzomib, a second-generation proteasome inhibitor, has clinical efficacy even among bortezomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de717a74eb573019c64d9f699db36f2e
https://doi.org/10.1158/1078-0432.ccr-18-1909
https://doi.org/10.1158/1078-0432.ccr-18-1909
Autor:
Peter M. Aldridge, Edward H. Sargent, Libing Zhang, Sae Rin Jean, Sharif Uddin Ahmed, Fengjia Fan, Shana O. Kelley, Xiyan Li
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications
Nature Communications
Biotemplated nanomaterials offer versatile functionality for multimodal imaging, biosensing, and drug delivery. There remains an unmet need for traceable and biocompatible nanomaterials that can be synthesized in a precisely controllable manner. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7275ad30690c01d1c0e1ead796912f0
http://link.springer.com/article/10.1038/s41467-017-00298-w
http://link.springer.com/article/10.1038/s41467-017-00298-w
Publikováno v:
Accounts of Chemical Research. 49:1893-1902
Mitochondria are organelles with critical roles in key processes within eukaryotic cells, and their dysfunction is linked with numerous diseases including neurodegenerative disorders and cancer. Pharmacological manipulation of mitochondrial function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d712642632f5c8f7b43dd7483cb86d3
https://doi.org/10.1021/acs.accounts.6b00277
https://doi.org/10.1021/acs.accounts.6b00277
Publikováno v:
Nature Chemical Biology. 12:567-573
Efficient and accurate replication and repair of mitochondrial DNA is essential for cellular viability, yet only a minimal complement of mitochondrial proteins with relevant activities have been identified. Here, we describe an approach to screen for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a6405d7b8f29df965d0a22a06b4e9f
https://doi.org/10.1038/nchembio.2102
https://doi.org/10.1038/nchembio.2102
Autor:
Tanja Sack, Jagotamoy Das, Edward H. Sargent, Xiyan Li, Shana O. Kelley, Alexandre Zaragoza, Sae Rin Jean, Gordon Chan, Zongjie Wang, Libing Zhang, Sharif Uddin Ahmed
Publikováno v:
Nano letters. 18(10)
Cytotoxic chemotherapeutics are important tools for the clinical treatment of a variety of solid tumors. However, their use is often complicated by multidrug resistance that can develop in patients, limiting the potencies of these agents. New strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc24f32ad3dc606bc97f9a3042f594
https://pubmed.ncbi.nlm.nih.gov/30188727
https://pubmed.ncbi.nlm.nih.gov/30188727
Autor:
Ilaria Dalla Rosa, Stephanie A. Michaels, Keli Agama, Simone A Baechler, Lisa M. Miller Jenkins, Salim Khiati, Valentina M. Factor, Yves Pommier, Shar-yin N. Huang, Sae Rin Jean, David V. Tulumello, Sudhir Varma, Junko Murai, Shana O. Kelley
Publikováno v:
EMBO Reports
EMBO Reports, EMBO Press, 2018, 19 (3), pp.e42139. ⟨10.15252/embr.201642139⟩
EMBO Reports, EMBO Press, 2018, 19 (3), pp.e42139. ⟨10.15252/embr.201642139⟩
Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs abortive topoisomerase II cleavage complexes. Here, we identify a novel short isoform of TDP2 (TDP2S) expressed from an alternative transcription start site. TDP2S contains a mitochondrial targeting sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c105ffa143075ed5117c15840bee30f9
https://doi.org/10.15252/embr.201642139
https://doi.org/10.15252/embr.201642139