Zobrazeno 1 - 10
of 505
pro vyhledávání: '"Sadovnick AD"'
Multiple Sclerosis (MS) is a common chronic central nervous system disease in young adults. Relative familial risk appears to be determined largely by genes while population risk is strongly influenced by environmental factors. This is supported by g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::84aad816098871d90c8f70fe738826bf
https://doi.org/10.1093/hmg/6.10.1693
https://doi.org/10.1093/hmg/6.10.1693
Multiple sclerosis (MS) is now thought to be a complex trait determined by genetic and non-genetic (environmental) factors. The study group, identified from the Canadian Collaborative Project on Genetic Susceptibility to MS, consisted of 1,083 MS ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::18777c7f6f45669ef0f57c7921ccfdb5
https://doi.org/10.1034/j.1399-0004.2000.580602.x
https://doi.org/10.1034/j.1399-0004.2000.580602.x
From a population-based sample of 15,504 patients attending Canadian multiple sclerosis (MS) clinics, we have determined the frequency of conjugal MS and have estimated the recurrence risk in offspring of such matings. Twenty-three MS cases were foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a550f5ca03cdf46b05f2c51bb9879c42
https://ora.ox.ac.uk/objects/uuid:d85a3903-5d32-4fd9-b23f-3181fee4fad3
https://ora.ox.ac.uk/objects/uuid:d85a3903-5d32-4fd9-b23f-3181fee4fad3
Background: Results from the Canadian Collaborative Project on Genetic Susceptibility to Multiple Sclerosis (MS)-Phase 1 (CCPGSMS-Phase 1) together with other family data published since 1982 have led to the following conclusions about the etiology o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::11bbce416a9e0e1526e437cdbdac91b6
https://ora.ox.ac.uk/objects/uuid:037284f5-2370-42cd-9f71-f2ac0884f75d
https://ora.ox.ac.uk/objects/uuid:037284f5-2370-42cd-9f71-f2ac0884f75d
The objective of this study was to investigate genes involved in the metabolism and function of vitamin D as candidate genes for genetic susceptibility to MS. Restriction fragment length polymorphisms and highly polymorphic microsatellite markers wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::44d10efdde3986537b7c4b664e3719be
https://ora.ox.ac.uk/objects/uuid:4edd01c9-d046-4e8f-b95c-030a76235ae7
https://ora.ox.ac.uk/objects/uuid:4edd01c9-d046-4e8f-b95c-030a76235ae7
Autor:
Ramagopalan, SV, Valdar, W, Dyment, DA, DeLuca, GC, Yee, IM, Giovannoni, G, Ebers, GC, Sadovnick, AD
BACKGROUND: Genetic and environmental factors have important roles in multiple sclerosis (MS) susceptibility. Several studies have attempted to correlate exposure to viral illness with the subsequent development of MS. Here in a population-based Cana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bf528bd8f5af05b5906d35d0b7f0e7bb
https://doi.org/10.1159/000201564
https://doi.org/10.1159/000201564
Autor:
Ramagopalan, SV, Byrnes, JK, Orton, SM, Dyment, DA, Guimond, C, Yee, IM, Ebers, GC, Sadovnick, AD
BACKGROUND AND PURPOSE: In a longitudinal population-based dataset of patients with multiple sclerosis (MS), we have previously observed a substantial increase in the female to male sex ratio in Canada over the last 50 years. Here, we aimed to determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e95c695b813a8fd75dc4144700ae56bf
https://doi.org/10.1111/j.1468-1331.2009.02850.x
https://doi.org/10.1111/j.1468-1331.2009.02850.x
The objective of this study was to investigate genes involved in the metabolism and function of vitamin D as candidate genes for genetic susceptibility to MS. Restriction fragment length polymorphisms and highly polymorphic microsatellite markers wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::904abdd5cfda3ff3535d18be0b9c8b8d
https://doi.org/10.1212/wnl.54.3.729
https://doi.org/10.1212/wnl.54.3.729
BACKGROUND: Results from the Canadian Collaborative Project on Genetic Susceptibility to Multiple Sclerosis (MS)-Phase 1 (CCPGSMS-Phase 1) together with other family data published since 1982 have led to the following conclusions about the etiology o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f7af7a78c4d0d6e8d169a61d68abdadf
https://ora.ox.ac.uk/objects/uuid:3b3651db-ce7e-4ee3-9430-4a0608a7a002
https://ora.ox.ac.uk/objects/uuid:3b3651db-ce7e-4ee3-9430-4a0608a7a002