Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sadie Miki, Sakurada"'
Autor:
Carolyn M Jablonowski, Waise Quarni, Shivendra Singh, Haiyan Tan, Dhanushka Hewa Bostanthirige, Hongjian Jin, Jie Fang, Ti-Cheng Chang, David Finkelstein, Ji-Hoon Cho, Dongli Hu, Vishwajeeth Pagala, Sadie Miki Sakurada, Shondra M Pruett-Miller, Ruoning Wang, Andrew Murphy, Kevin Freeman, Junmin Peng, Andrew M Davidoff, Gang Wu, Jun Yang
Publikováno v:
eLife, Vol 12 (2024)
Dysregulated pre-mRNA splicing and metabolism are two hallmarks of MYC-driven cancers. Pharmacological inhibition of both processes has been extensively investigated as potential therapeutic avenues in preclinical and clinical studies. However, how p
Externí odkaz:
https://doaj.org/article/56c3296c6a1943a796dba4f0a49cdf21
Autor:
Tae-Yeon Eom, Seung Baek Han, Jieun Kim, Jay A. Blundon, Yong-Dong Wang, Jing Yu, Kara Anderson, Damian B. Kaminski, Sadie Miki Sakurada, Shondra M. Pruett-Miller, Linda Horner, Ben Wagner, Camenzind G. Robinson, Matthew Eicholtz, Derek C. Rose, Stanislav S. Zakharenko
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Schizophrenia is associated with brain ventricular enlargement. Here, the authors show in mice that 22q11 deletion, which is associated with schizophrenia, causes ventricular enlargement and motility abnormalities in cilia lining ventricle walls via
Externí odkaz:
https://doaj.org/article/015f5351a7344fa99035595c0123d9f5
Autor:
Jung Mi Park, Seung Wook Yang, Wei Zhuang, Asim K Bera, Yan Liu, Deepak Gurbani, Sergei J von Hoyningen-Huene, Sadie Miki Sakurada, Haiyun Gan, Shondra M Pruett-Miller, Kenneth D Westover, Malia B Potts
Publikováno v:
PLoS Biology, Vol 19, Iss 6, p e3001281 (2021)
Nutrient-responsive protein kinases control the balance between anabolic growth and catabolic processes such as autophagy. Aberrant regulation of these kinases is a major cause of human disease. We report here that the vertebrate nonreceptor tyrosine
Externí odkaz:
https://doaj.org/article/4164afef6c64473eae9b0a547aaea3fd
Autor:
Daniel P Stewart, Suresh Marada, William J Bodeen, Ashley Truong, Sadie Miki Sakurada, Tanushree Pandit, Shondra M Pruett-Miller, Stacey K Ogden
Publikováno v:
eLife, Vol 7 (2018)
Hedgehog ligands activate an evolutionarily conserved signaling pathway that provides instructional cues during tissue morphogenesis, and when corrupted, contributes to developmental disorders and cancer. The transmembrane protein Dispatched is an es
Externí odkaz:
https://doaj.org/article/47906c4901864f01979c6e61b3553507
Autor:
Shondra M. Pruett-Miller, Melvin Edward Thomas, Jason R. Schwartz, Guangchun Song, Jing Ma, Jeffery M. Klco, Michael Walsh, Sadie Miki Sakurada, Ryan Hiltenbrand, Sherif Abdelhamed
Publikováno v:
Leukemia
Pediatric myelodysplastic syndromes (MDS) are a heterogeneous disease group associated with impaired hematopoiesis, bone marrow hypocellularity, and frequently have deletions involving chromosome 7 (monosomy 7). We and others recently identified hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a476dba9bb46772655b88cd31a1f4cf2
https://doi.org/10.1038/s41375-021-01212-6
https://doi.org/10.1038/s41375-021-01212-6
Autor:
Swarna, Beesetti, Shyam, Sirasanagandla, Sadie Miki, Sakurada, Shondra M, Pruett-Miller, Rhea, Sumpter, Beth, Levine, Malia B, Potts
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166453
Fanconi anemia (FA) is the most common inherited bone marrow failure syndrome. The FA proteins have functions in genome maintenance and in the cytoplasmic process of selective autophagy, beyond their canonical roles of repairing DNA interstrand cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45ca2a304842c8e4615a3c99e4f4fe9
https://doi.org/10.1016/j.bbadis.2022.166453
https://doi.org/10.1016/j.bbadis.2022.166453
Autor:
Shondra M. Pruett-Miller, Malia B. Potts, Yan Liu, Sadie Miki Sakurada, Asim K. Bera, Sergei J. von Hoyningen-Huene, Kenneth D. Westover, Deepak Gurbani, Haiyun Gan, Wei Zhuang, Jung Mi Park, Seung Wook Yang
Publikováno v:
PLoS Biology, Vol 19, Iss 6, p e3001281 (2021)
PLoS Biology
PLoS Biology
Nutrient-responsive protein kinases control the balance between anabolic growth and catabolic processes such as autophagy. Aberrant regulation of these kinases is a major cause of human disease. We report here that the vertebrate nonreceptor tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d14255d08b0e169bebabf712a73308f
https://doaj.org/article/4164afef6c64473eae9b0a547aaea3fd
https://doaj.org/article/4164afef6c64473eae9b0a547aaea3fd
Autor:
Zhenya Hong, Jane E. Craig, Taosheng Chen, Lily Jun Shen Huang, Wei Zhuang, Gamze B. Bulut, Sadie Miki Sakurada, Jonathan Low, Malia B. Potts, Jamshid Temirov, Joseph N. Miller, Raju R. Rayavarapu, Shondra M. Pruett-Miller
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Mitochondria are vital organelles that coordinate cellular energy homeostasis and have important roles in cell death. Therefore, the removal of damaged or excessive mitochondria is critical for maintaining proper cellular function. The PINK1-Parkin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e35506dd5c5cc74f18ba5897b121cc5
https://pubmed.ncbi.nlm.nih.gov/33101709
https://pubmed.ncbi.nlm.nih.gov/33101709
Autor:
Jieun Kim, Derek C. Rose, Seung Baek Han, Kara Anderson, Yong-Dong Wang, Jing Yu, Matthew Eicholtz, Camenzind G. Robinson, Sadie Miki Sakurada, Ben Wagner, Jay A. Blundon, Stanislav S. Zakharenko, Tae-Yeon Eom, Shondra M. Pruett-Miller, Linda Horner, Damian B. Kaminski
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Progressive ventricular enlargement, a key feature of several neurologic and psychiatric diseases, is mediated by unknown mechanisms. Here, using murine models of 22q11-deletion syndrome (22q11DS), which is associated with schizophrenia in humans, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cde0810d3bec010a7d00ffc6450a38
http://europepmc.org/articles/PMC7021727
http://europepmc.org/articles/PMC7021727
Autor:
Suresh Marada, William J. Bodeen, Daniel P. Stewart, Ashley Truong, Sadie Miki Sakurada, Stacey K. Ogden, Shondra M. Pruett-Miller, Tanushree Pandit
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Hedgehog ligands activate an evolutionarily conserved signaling pathway that provides instructional cues during tissue morphogenesis, and when corrupted, contributes to developmental disorders and cancer. The transmembrane protein Dispatched is an es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f032d1525fdcdffedbafbfaf64f4e0a9
https://doi.org/10.7554/elife.31678
https://doi.org/10.7554/elife.31678