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A family of NADPH/NADP ⁺ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes.

Autor: Scherschel M; Institute of Biochemistry, Center for Human and Molecular Biology (ZHMB), Saarland University, Saarbrücken, Germany., Niemeier JO; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Jacobs LJHC; Redox Metabolism, Institute for Biochemistry, University of Cologne, Cologne, Germany., Hoffmann MDA; Department of Biophysics, Center for Human and Molecular Biology (ZHMB), Saarland University, Homburg, Germany., Diederich A; Institute of Biochemistry, Center for Human and Molecular Biology (ZHMB), Saarland University, Saarbrücken, Germany., Bell C; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Höhne P; Institute of Biochemistry, Center for Human and Molecular Biology (ZHMB), Saarland University, Saarbrücken, Germany.; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Raetz S; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Kroll JB; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Steinbeck J; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Lichtenauer S; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Multhoff J; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany., Zimmermann J; Institute of Biochemistry, Center for Human and Molecular Biology (ZHMB), Saarland University, Saarbrücken, Germany., Sadhanasatish T; Institute of Integrative Cell Biology and Physiology, University of Münster, Schlossplatz 5, Münster, Germany., Rothemann RA; Redox Metabolism, Institute for Biochemistry, University of Cologne, Cologne, Germany., Grashoff C; Institute of Integrative Cell Biology and Physiology, University of Münster, Schlossplatz 5, Münster, Germany., Messens J; VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium., Ampofo E; Institute for Clinical & Experimental Surgery, Saarland University, Homburg, Germany., Laschke MW; Institute for Clinical & Experimental Surgery, Saarland University, Homburg, Germany., Riemer J; Redox Metabolism, Institute for Biochemistry, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany., Roma LP; Department of Biophysics, Center for Human and Molecular Biology (ZHMB), Saarland University, Homburg, Germany., Schwarzländer M; Institute of Plant Biology and Biotechnology, University of Münster, Schlossplatz 8, Münster, Germany. markus.schwarzlander@uni-muenster.de., Morgan B; Institute of Biochemistry, Center for Human and Molecular Biology (ZHMB), Saarland University, Saarbrücken, Germany. bruce.morgan@uni-saarland.de.

Publikováno v: Nature communications [Nat Commun] 2024 Dec 19; Vol. 15 (1), pp. 10704. Date of Electronic Publication: 2024 Dec 19.