Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Sadhan, Das"'
Autor:
Mitsuo Kato, Zhuo Chen, Sadhan Das, Xiwei Wu, Jinhui Wang, Arthur Li, Wei Chen, Walter Tsark, Ragadeepthi Tunduguru, Linda Lanting, Mei Wang, Roger Moore, Markus Kalkum, Maryam Abdollahi, Rama Natarajan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play key roles in diabetic kidney disease (DKD). The miR-379 megacluster of miRNAs and its host transcript lnc-megacluster (lncMGC) are regulated by transforming growth factor-β (TGF-
Externí odkaz:
https://doaj.org/article/44374e3670e84c119d07b8ac603d7f01
Autor:
Marpadga A. Reddy, Vishnu Amaram, Sadhan Das, Vinay Singh Tanwar, Rituparna Ganguly, Mei Wang, Linda Lanting, Lingxiao Zhang, Maryam Abdollahi, Zhuo Chen, Xiwei Wu, Sridevi Devaraj, Rama Natarajan
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Long noncoding RNAs (lncRNAs) are increasingly implicated in the pathology of diabetic complications. Here, we examined the role of lncRNAs in monocyte dysfunction and inflammation associated with human type 2 diabetes mellitus (T2D). RNA sequencing
Externí odkaz:
https://doaj.org/article/5f467a5642364bdc98a43bb2b160a7be
Autor:
Vishnu Amaram Samara, Sadhan Das, Marpadga A. Reddy, Vinay Singh Tanwar, Kenneth Stapleton, Amy Leung, Maryam Abdollahi, Rituparna Ganguly, Linda Lanting, Rama Natarajan
Publikováno v:
Cells, Vol 10, Iss 10, p 2696 (2021)
Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown. We describe a novel AngII-induced lncRNA Alivec (Angiotensin II-induce
Externí odkaz:
https://doaj.org/article/bf30d0f40d4f4e429a491aaf3b6ff8e0
Autor:
Sadhan Das, Parijat Senapati, Zhuo Chen, Marpadga A. Reddy, Rituparna Ganguly, Linda Lanting, Varun Mandi, Anita Bansal, Amy Leung, Selena Zhang, Ye Jia, Xiwei Wu, Dustin E. Schones, Rama Natarajan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
The repertoire of tissue-specific distal regulators of gene transcription enhancers defines homeostasis or disease. Here, the authors reveal the enhancer and super-enhancer signature of vascular smooth muscle cells under normal and angiotensin II sti
Externí odkaz:
https://doaj.org/article/c12c799c38c64e36a32adeb8061e24ec
Autor:
Sanjeev Kumar, Elizabhet Cruz Gomez, Mounira Chalabi-Dchar, Cong Rong, Sadhan Das, Iva Ugrinova, Xavier Gaume, Karine Monier, Fabien Mongelard, Philippe Bouvet
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Nucleolin is an essential protein that plays important roles in the regulation of cell cycle and cell proliferation. Its expression is up regulated in many cancer cells but its molecular functions are not well characterized. Nucleolin is pre
Externí odkaz:
https://doaj.org/article/10a72c2701d349e4b3c802e0984c0e05
Autor:
Vinay Singh Tanwar, Marpadga A. Reddy, Sadhan Das, Vishnu Amaram Samara, Maryam Abdollahi, Suchismita Dey, Vajir Malek, Rituparna Ganguly, Kenneth Stapleton, Linda Lanting, Patrick Pirrotte, Rama Natarajan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
Background: Obesity and diabetes are associated with elevated free fatty acids like palmitic acid (PA), which promote chronic inflammation and impaired inflammation resolution associated with cardiometabolic disorders. Long noncoding RNAs (lncRNAs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55a55e54878fd9a453bf14c2d9e1da6
https://doi.org/10.1161/atvbaha.122.318536
https://doi.org/10.1161/atvbaha.122.318536
Autor:
VINAY S. TANWAR, MARPADGA A. REDDY, SADHAN DAS, VISHNU AMARAM SAMARA, MARYAM ABDOLLAHI, SUCHISMITA DEY, RITUPARNA GANGULY, LINDA L. LANTING, KENNETH STAPLETON, RAMA NATARAJAN
Publikováno v:
Diabetes. 71
Obesity and diabetes are associated with chronic inflammation induced by the elevated circulating levels of Palmitic acid (PA) and also result from impaired resolution of inflammation in macrophages. Here, we examined the role of PA-induced long non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37b6f6560a56dce47d62a1431000640
https://doi.org/10.2337/db22-451-p
https://doi.org/10.2337/db22-451-p
Autor:
Parijat Senapati, Aditya Bhattacharya, Sadhan Das, Suchismita Dey, Deepthi Sudarshan, Shyla G, Jyoti Vishwakarma, Surabhi Sudevan, Ravishankar Ramachandran, Tessy Thomas Maliekal, Tapas K. Kundu
Publikováno v:
Mol Cell Biol
Nucleophosmin (NPM1) is a multifunctional histone chaperone that can activate acetylation-dependent transcription from chromatin templates in vitro. p300-mediated acetylation of NPM1 has been shown to further enhance its transcription activation pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d76a3514ef450b3bf053592a75ba796
https://doi.org/10.1096/fasebj.2022.36.s1.r4402
https://doi.org/10.1096/fasebj.2022.36.s1.r4402
Publikováno v:
Curr Opin Cardiol
Purpose of review Hyperlipidemia, hypertension, diabetes and related metabolic disorders increase the risk for cardiovascular disease (CVD). Despite significant progress in the identification of key mechanisms and genetic polymorphisms linked to vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313cb33649f0deb98865490134315222
https://doi.org/10.1097/hco.0000000000000728
https://doi.org/10.1097/hco.0000000000000728
Autor:
Rengasamy Palanivel, Rama Natarajan, Lingxiao Zhang, Vishnu Amaram, Jeffrey A. Deiuliis, Kenneth Stapleton, Zhuo Chen, Linda Lanting, Marpadga A. Reddy, Sadhan Das, Amy Leung
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:914-928
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular complications. This inflammatory state is caused by release of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d316219af70957369e6209b411253e8d
https://doi.org/10.1161/atvbaha.119.313359
https://doi.org/10.1161/atvbaha.119.313359