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Synthesis and Physicochemical Characterization of a Diethyl Ester Prodrug of DTPA and Its Investigation as an Oral Decorporation Agent in Rats.

Autor: Huckle JE; UNC Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina at Chapel Hill, 125 Mason Farm Road, CB #7362, Chapel Hill, NC, 27599-7362, USA., Sadgrove MP; UNC Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina at Chapel Hill, 125 Mason Farm Road, CB #7362, Chapel Hill, NC, 27599-7362, USA., Leed MG; UNC Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina at Chapel Hill, 125 Mason Farm Road, CB #7362, Chapel Hill, NC, 27599-7362, USA., Yang YT; UNC Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina at Chapel Hill, 125 Mason Farm Road, CB #7362, Chapel Hill, NC, 27599-7362, USA., Mumper RJ; UNC Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina at Chapel Hill, 125 Mason Farm Road, CB #7362, Chapel Hill, NC, 27599-7362, USA., Semelka RC; School of Medicine, Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jay M; UNC Eshelman School of Pharmacy, Division of Molecular Pharmaceutics, University of North Carolina at Chapel Hill, 125 Mason Farm Road, CB #7362, Chapel Hill, NC, 27599-7362, USA. mjay@unc.edu.

Publikováno v: The AAPS journal [AAPS J] 2016 Jul; Vol. 18 (4), pp. 972-80. Date of Electronic Publication: 2016 Apr 22.

Orally administered DTPA di-ethyl ester for decorporation of (241)Am in dogs: Assessment of safety and efficacy in an inhalation-contamination model.

Autor: Huckle JE; University of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Division of Molecular Pharmaceutics , Chapel Hill , NC., Sadgrove MP, Pacyniak E, Leed MG, Weber WM, Doyle-Eisele M, Guilmette RA, Agha BJ, Susick RL, Mumper RJ, Jay M

Publikováno v: International journal of radiation biology [Int J Radiat Biol] 2015 Jul; Vol. 91 (7), pp. 568-75. Date of Electronic Publication: 2015 May 21.

Age-related metabolic fatigue during low glucose conditions in rat hippocampus.

Autor: Galeffi F; Department of Surgery (Neurosurgery), Duke University Medical Center, Durham, NC, USA; Research and Surgery Services, Durham VAMC, Durham NC, USA. Electronic address: galeffi@duke.edu., Shetty PK; Department of Surgery (Neurosurgery), Duke University Medical Center, Durham, NC, USA; Research and Surgery Services, Durham VAMC, Durham NC, USA., Sadgrove MP; Department of Surgery (Neurosurgery), Duke University Medical Center, Durham, NC, USA; Research and Surgery Services, Durham VAMC, Durham NC, USA., Turner DA; Department of Surgery (Neurosurgery), Duke University Medical Center, Durham, NC, USA; Research and Surgery Services, Durham VAMC, Durham NC, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.

Publikováno v: Neurobiology of aging [Neurobiol Aging] 2015 Feb; Vol. 36 (2), pp. 982-92. Date of Electronic Publication: 2014 Sep 28.

Radionuclide decorporation: matching the biokinetics of actinides by transdermal delivery of pro-chelators.

Autor: Zhang Y; Division of Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, CB 7362, 120 Mason Farm Rd, Chapel Hill, North Carolina, 27599-7362, USA., Sadgrove MP, Mumper RJ, Jay M

Publikováno v: The AAPS journal [AAPS J] 2013 Oct; Vol. 15 (4), pp. 1180-8. Date of Electronic Publication: 2013 Aug 30.