Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options

Autor: Corley, Christa, Craig, Ashley, Sadek, Safiyah, Marusich, Julie A., Chehimi, Samar N., White, Ashley M., Holdiness, Lexi J., Reiner, Benjamin C., Gipson, Cassandra D.

Publikováno v: In Pharmacology, Biochemistry and Behavior October 2024 243

Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats

Autor: Khatri, Shailesh N., Ulangkaya, Hanaa, Maher, Erin E., Sadek, Safiyah, Hong, Mei, Woodcox, Andrea M., Stoops, William W., Gipson, Cassandra D.

Publikováno v: In Neuropharmacology 1 January 2024 242

Xylazine suppresses fentanyl consumption during self-administration and induces a unique sex-specific withdrawal syndrome that is not altered by naloxone in rats.

Autor: Khatri SN; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Sadek S; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Kendrick PT; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Bondy EO; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Hong M; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Pauss S; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Luo D; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky., Prisinzano TE; Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky., Dunn KE; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University., Marusich JA; Center for Drug Discovery, RTI International., Beckmann JS; Department of Psychology, University of Kentucky., Hinds TD; Department of Pharmacology and Nutritional Sciences, University of Kentucky., Gipson CD; Department of Pharmacology and Nutritional Sciences, University of Kentucky.

Publikováno v: Experimental and clinical psychopharmacology [Exp Clin Psychopharmacol] 2024 Apr; Vol. 32 (2), pp. 150-157. Date of Electronic Publication: 2023 Jul 20.