The IGF pathway is activated in insulinomas but downregulated in metastatic disease.

Autor: Henfling M; M Henfling, Genetics & Cell Biology, Maastricht University - Location Randwyck, Maastricht, Netherlands., Perren A; A Perren, University of Bern, Institute of Pathology, Bern, Switzerland., Schmitt AM; A Schmitt, Department of Pathology, University of Bern, Bern, Switzerland., Saddig CM; C Saddig, Insulinoma and GEP-Tumor Center Neuss-Düsseldorf, Klinik für Endokrine Chirurgie, Stadtische Kliniken Neuss Lukaskrankenhaus GmbH, Neuss, Germany., Starke AA; A Starke, Insulinoma and GEP-Tumor Center Neuss-Düsseldorf, Klinik für Endokrine Chirurgie, Stadtische Kliniken Neuss Lukaskrankenhaus GmbH, Neuss, Germany., Riedl RG; R Riedl, Pathology, Zuyderland Medisch Centrum Heerlen, Heerlen, Netherlands., Versleijen-Jonkers YMH; Y Versleijen-Jonkers, Medical Oncology, Radboud University Medical Centre, Nijmegen, Netherlands., Sprij-Mooij DM; D Sprij-Mooij, Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, Netherlands., Ramaekers FCS; F Ramaekers, Molecular Cell Biology, Maastricht University, Maastricht, Netherlands., Hofland L; L Hofland, Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, Netherlands., Speel EM; E Speel, Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands ernstjan.speel@mumc.nl.

Publikováno v: Endocrine-related cancer [Endocr Relat Cancer] 2018 Jul 18. Date of Electronic Publication: 2018 Jul 18.