Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sadayoshi Onodera"'
Autor:
Sadayoshi Onodera, Peter Y Shane
Publikováno v:
Drug Delivery System. 29:160-165
Autor:
Misao Aoyama, Niro Inaba, Bunsho Lee, Masato Tanaka, Yoko Arai, Masahiro Shibata, Tetsuaki Yamaura, Sadayoshi Onodera
Publikováno v:
Arzneimittelforschung. 49:519-526
Lafutidine (CAS 118288-08-7, FRG-8813) is a novel histamine H2-receptor antagonist with gastroprotective activity. The aim of this study was to investigate the property of the gastro-protective activity of lafutidine by examining the effect on ammoni
Publikováno v:
Drug Design Reviews - Online. 1:133-144
Autor:
Tsutomu Chiba, Yoshikazu Kinoshita, Sadayoshi Onodera, Nobuyuki Moriyama, Mohammad Azharul Karim Rumi, Hideaki Kazumori, Hiroshi Suetsugu, Ryo Fukuda, Shunji Ishihara, Kyoichi Adachi, Kousaku Kawashima, H. Sato, Masahiro Shibata
Publikováno v:
Peptides. 23:955-966
The location of calcitonin gene-related peptide (CGRP) receptors in the rat stomach has not been elucidated. It was recently reported that the CGRP receptor is formed when a calcitonin-receptor-like receptor (CRLR) and receptor activity modifying pro
Autor:
Masato Tanaka, Misao Aoyama, Sadayoshi Onodera, Haruo Ohnishi, Tetsuaki Yamaura, Masahiro Shibata, Yoko Arai
Publikováno v:
Folia Pharmacologica Japonica. 111:167-175
Effect of lafutidine ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2-pyr idyl] oxy-(Z)-2-butenyl] acetamide, FRG-8813), a novel antiulcer agent, on the healing and relapse in acetic acid-induced gastric ulcer in rats was investigated. Lafuti
Autor:
Niro Inaba, Sadayoshi Onodera, Masatoyo Kagoshima, Hideyo Shimada, Tetsuaki Yamaura, Terue Suzuki, Masahiro Shibata
Publikováno v:
Digestive Diseases and Sciences. 42:1242-1254
The effect of chemical deafferentation, vagotomy (VGX), and gangliosympathectomy (GSX) on the density of fibers containing calcitonin gene-related peptide (CGRP) and substance P (Sub.P) in the rat gastric wall was studied. Chemical deafferentation by
Autor:
Sadayoshi Onodera, Masato Tanaka, Takao Suzuki, Tetsuaki Yamaura, Niro Inaba, Masahiro Shibata
Publikováno v:
Folia Pharmacologica Japonica. 109:31-40
Oral administration of an ammonia solution (0.01%) or a sodium taurocholate solution (TCA solution, 5 mM) as drinking water for 4 weeks or 13 weeks, respectively, resulted in gastric mucosal thinning and decreased parietal cell numbers. Oral administ
Autor:
Niro Inaba, Tetsuaki Yamaura, Sadayoshi Onodera, Haruo Ohnishi, Masato Tanaka, Masahiro Shibata
Publikováno v:
Japanese Journal of Pharmacology. 68:161-173
FRG-8813 ((+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2- pyridyl]oxy-(Z)-2-butenyl]acetamide) is a novel histamine H2-receptor antagonist with gastric antisecretory and gastroprotective activities. The present study was designed to investig
Autor:
Sadayoshi Onodera, Atsushi Toyoshima, Masaichi Yoshinaga, Kunizou Takenaga, Toshimitsu Uchiyama
Publikováno v:
Folia Pharmacologica Japonica. 96:103-115
We investigated the effects of several autonomic nervous system-related agents on the intravesical pressure (IVP) in adult (11-23 weeks old, 200-350 g) and aged (2 years old, 350-770 g) female rats. Acetylcholine induced a dose-dependent and transien
Autor:
Akinori Mochizuki, Toru Hiruma, Niro Inaba, Hisao Tomioka, Sadayoshi Onodera, Yoriko Yatabe, Norihiko Tamura, Jun Kusunoki
Publikováno v:
European journal of pharmacology. 430(1)
We investigated the effects of F-1322 (N-[2-[4-(benzhydryloxy)piperidino]ethyl]-3-hydroxy-5-(3-pyridylmethoxy)-2-naphthamide), a new compound that inhibits both thromboxane A2 synthetase and 5-lipoxygenase and that functions as a histamine antagonist