Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Sadanandan E Velu"'
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001097 (2021)
The oncogenic human herpesviruses Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) are the causative agents of multiple malignancies. A hallmark of herpesviruses is their biphasic life cycle consisting of latent and lytic i
Externí odkaz:
https://doaj.org/article/7ea99c7f5cdc4a29ac5dafc4e345acce
Autor:
Praveen K Vayalil, Joo-Yeun Oh, Fen Zhou, Anne R Diers, M Ryan Smith, Hafez Golzarian, Patsy G Oliver, Robin A J Smith, Michael P Murphy, Sadanandan E Velu, Aimee Landar
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120460 (2015)
Despite advances in screening and treatment over the past several years, breast cancer remains a leading cause of cancer-related death among women in the United States. A major goal in breast cancer treatment is to develop safe and clinically useful
Externí odkaz:
https://doaj.org/article/12e59c8641af42228ba786a8797bd8f0
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
This review focuses on the expression and function of voltage-gated sodium channel subtype NaV1.7 in various cancers and explores its impact on the metastasis driving cell functions such as proliferation, migration, and invasiveness. An overview of i
Externí odkaz:
https://doaj.org/article/38393a0ff2444ac094ff1c743b83f820
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTThe tenacious biofilms formed by Streptococcus mutans are resistant to conventional antibiotics and current treatments. There is a growing need for novel therapeutics that selectively inhibit S. mutans biofilms while preserving the normal ora
Externí odkaz:
https://doaj.org/article/23c6ad2ad94043df8e38e0562d2dec85
Autor:
Kim M Keeling, Dan Wang, Yanying Dai, Srinivasan Murugesan, Balachandra Chenna, Jeremy Clark, Valery Belakhov, Jeyakumar Kandasamy, Sadanandan E Velu, Timor Baasov, David M Bedwell
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60478 (2013)
Nonsense suppression therapy is an approach to treat genetic diseases caused by nonsense mutations. This therapeutic strategy pharmacologically suppresses translation termination at Premature Termination Codons (PTCs) in order to restore expression o
Externí odkaz:
https://doaj.org/article/65b49f1f65d24a4cb10e23580a3d869b
Autor:
Tao Chen, Yi Xu, He Guo, Yanling Liu, Pingting Hu, Xinying Yang, Xiaoguang Li, Shichao Ge, Sadanandan E Velu, Dwayaja H Nadkarni, Wei Wang, Ruiwen Zhang, Hui Wang
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20729 (2011)
The present study was designed to determine the biological effects of novel marine alkaloid analog 7-(4-fluorobenzylamino)-1,3,4,8-tetrahydropyrrolo[4,3,2-de]quinolin-8(1H)-one (FBA-TPQ) on human ovarian cancer cells for its anti-tumor potential and
Externí odkaz:
https://doaj.org/article/10d01fb7aca846499ab19bf3bcc17f1c
Autor:
Piyasuda Pukkanasut, Jason Whitt, Rachael Guenter, Shannon E. Lynch, Carlos Gallegos, Margarita Jacaranda Rosendo-Pineda, Juan Carlos Gomora, Herbert Chen, Diana Lin, Anna Sorace, Renata Jaskula-Sztul, Sadanandan E. Velu
Publikováno v:
Cancers; Volume 15; Issue 10; Pages: 2806
Our results from quantitative RT-PCR, Western blotting, immunohistochemistry, and the tissue microarray of medullary thyroid cancer (MTC) cell lines and patient specimens confirm that VGSC subtype NaV1.7 is uniquely expressed in aggressive MTC and no
Autor:
Sunil Sudarshan, Conrad Kunick, Anja Becker, Devin Absher, Tony Huang, Jason Chen, Alison Pan, Ethan Emberley, Sadanandan E. Velu, Shilpa Dutta, Seishi Ogawa, Yusuke Sato, Richard Kirkman, Dinesh Rakheja, Phillip J. Buckhaults, David K. Crossman, Daniel Benson, Vishwas Parekh, Jubilee Tan, Tyler Poston, Francesca Carobbio, Anirban Kundu, Garrett J. Brinkley, Eun-Hee Shim, Sandeep Shelar
Purpose:Elevation of L-2-hydroxylgutarate (L-2-HG) in renal cell carcinoma (RCC) is due in part to reduced expression of L-2-HG dehydrogenase (L2HGDH). However, the contribution of L-2-HG to renal carcinogenesis and insight into the biochemistry and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8a7332380cb20b611f1b22ee0bd469
https://doi.org/10.1158/1078-0432.c.6526647
https://doi.org/10.1158/1078-0432.c.6526647
Autor:
Sunil Sudarshan, Conrad Kunick, Anja Becker, Devin Absher, Tony Huang, Jason Chen, Alison Pan, Ethan Emberley, Sadanandan E. Velu, Shilpa Dutta, Seishi Ogawa, Yusuke Sato, Richard Kirkman, Dinesh Rakheja, Phillip J. Buckhaults, David K. Crossman, Daniel Benson, Vishwas Parekh, Jubilee Tan, Tyler Poston, Francesca Carobbio, Anirban Kundu, Garrett J. Brinkley, Eun-Hee Shim, Sandeep Shelar
Supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719fb94193e947bf4afe516bdbef5530
https://doi.org/10.1158/1078-0432.22467453.v1
https://doi.org/10.1158/1078-0432.22467453.v1
Autor:
Sunil Sudarshan, Conrad Kunick, Anja Becker, Devin Absher, Tony Huang, Jason Chen, Alison Pan, Ethan Emberley, Sadanandan E. Velu, Shilpa Dutta, Seishi Ogawa, Yusuke Sato, Richard Kirkman, Dinesh Rakheja, Phillip J. Buckhaults, David K. Crossman, Daniel Benson, Vishwas Parekh, Jubilee Tan, Tyler Poston, Francesca Carobbio, Anirban Kundu, Garrett J. Brinkley, Eun-Hee Shim, Sandeep Shelar
This table reports L2HGDH mRNA expression as a function of 14q Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa8964eb6ea55a5ff3bb2bfc45f3fdf
https://doi.org/10.1158/1078-0432.22467456.v1
https://doi.org/10.1158/1078-0432.22467456.v1