Zobrazeno 1 - 10
of 655
pro vyhledávání: '"Sadanandan, P."'
Autor:
Shilpa John, Sudha Ramani, Syed Mohd Abbas, Sumit Kane, Dorothy Lall, Prashanth N. Srinivas, Devaki Nambiar, Bruno Marchal, Sara Van Belle, Rajeev Sadanandan, Narayanan Devadasan
Publikováno v:
Health Research Policy and Systems, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Building capacity for Health Policy and Systems Research (HPSR) is critical for advancing the field in lower- and middle-income countries (LMICs). The India HPSR fellowship program is a home-grown capacity-building initiative, anchored at th
Externí odkaz:
https://doaj.org/article/284a1da3b77045dcab3f991f727b974c
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background The choroid plexus (CP) is an understudied tissue in the central nervous system and is primarily implicated in cerebrospinal fluid (CSF) production. CP also produces numerous neurotrophic factors (NTF) which circulate to different
Externí odkaz:
https://doaj.org/article/e486de3605594b62a1f5275cc1f5d024
Autor:
Jayanarayanan Sadanandan, Sithara Thomas, Iny Elizabeth Mathew, Zhen Huang, Spiros L Blackburn, Nitin Tandon, Hrishikesh Lokhande, Pierre D McCrea, Emery H Bresnick, Pramod K Dash, Devin W McBride, Arif Harmanci, Lalit K Ahirwar, Dania Jose, Ari C Dienel, Hussein A Zeineddine, Sungha Hong, Peeyush Kumar T
Publikováno v:
eLife, Vol 12 (2024)
The blood-brain barrier (BBB) controls the movement of molecules into and out of the central nervous system (CNS). Since a functional BBB forms by mouse embryonic day E15.5, we reasoned that gene cohorts expressed in CNS endothelial cells (EC) at E13
Externí odkaz:
https://doaj.org/article/91728f668ee24577ab941c3ffe5ed195
Autor:
Anila George, Poornasree Sadanandan, Nithin Sam Ravi, B. Vaishnavi, Srujan Marepally, Saravanbhavan Thangavel, Shaji R. Velayudhan, Alok Srivastava, Kumarasamypet M Mohankumar
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102347- (2024)
Recent studies have shown that base editing, even with single-strand breaks, could result in large deletions of the interstitial regions while targeting homologous regions. Several therapeutically relevant genes such as HBG, HBB, CCR5, and CD33 have
Externí odkaz:
https://doaj.org/article/16c6ab9d93df4d0791d211dc6272b842
Publikováno v:
Biosensors and Bioelectronics: X, Vol 20, Iss , Pp 100531- (2024)
The detection of clinically important disease-specific biomarkers such as proteins, nucleic acids, antibodies, enzymes, viruses and circulating tumor cells is essential for understanding their role in disease diagnosis and prognosis. Thus, current cl
Externí odkaz:
https://doaj.org/article/da47192a84a944f9bf422972dff852dd
Autor:
Minmini Selvam, Anupama Chandrasekharan, Abjasree Sadanandan, Vikas K. Anand, Sidharth Ramesh, Arunan Murali, Ganapathy Krishnamurthi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This observational study investigated the potential of radiomics as a non-invasive adjunct to CT in distinguishing COVID-19 lung nodules from other benign and malignant lung nodules. Lesion segmentation, feature extraction, and machine learn
Externí odkaz:
https://doaj.org/article/77915263635743b89d40dfe8fe3bf48c
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 02, Pp 21-24 (2024)
Introduction: Ovarian tumours are among the most common tumours in females, exhibiting diverse histopathological patterns that remain crucial for early diagnosis. Proper classification of ovarian neoplasms, particularly malignant ones, is essential f
Externí odkaz:
https://doaj.org/article/0b88412c3fbd450a9c839fb6296b3a22
Autor:
Shilpa John, Sudha Ramani, Syed Mohd Abbas, Sumit Kane, Dorothy Lall, Prashanth N. Srinivas, Devaki Nambiar, Bruno Marchal, Sara Van Belle, Rajeev Sadanandan, Narayanan Devadasan
Publikováno v:
Health Research Policy and Systems, Vol 22, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/574463e6d92c4021a5e98d4d1d3dd8e8
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
This review focuses on the expression and function of voltage-gated sodium channel subtype NaV1.7 in various cancers and explores its impact on the metastasis driving cell functions such as proliferation, migration, and invasiveness. An overview of i
Externí odkaz:
https://doaj.org/article/38393a0ff2444ac094ff1c743b83f820
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTThe tenacious biofilms formed by Streptococcus mutans are resistant to conventional antibiotics and current treatments. There is a growing need for novel therapeutics that selectively inhibit S. mutans biofilms while preserving the normal ora
Externí odkaz:
https://doaj.org/article/23c6ad2ad94043df8e38e0562d2dec85