Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sadanan Velu"'
Autor:
Sunil Sudarshan, Karen Block, Shi Wei, Sejong Bae, Lining Guo, Teresa L. Johnson-Pais, Qiuhua Li, Robert J. Mishur, Shane L. Rea, Balachandra Chenna, Shilpa Dutta, Sadanan Velu, Richard Kirkman, Arindam P. Ghosh, Eun-Young Kho, Vishwas Parekh, Daniel Benson, Jubilee Tan, Dinesh Rakheja, Carolina B. Livi, Eun-Hee Shim
Supplementary Table 2. VHL Genotyping in High L-2HG Tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53418bb2aac21fd11aff35ef194b82fa
https://doi.org/10.1158/2159-8290.22530497.v1
https://doi.org/10.1158/2159-8290.22530497.v1
Autor:
Sunil Sudarshan, Karen Block, Shi Wei, Sejong Bae, Lining Guo, Teresa L. Johnson-Pais, Qiuhua Li, Robert J. Mishur, Shane L. Rea, Balachandra Chenna, Shilpa Dutta, Sadanan Velu, Richard Kirkman, Arindam P. Ghosh, Eun-Young Kho, Vishwas Parekh, Daniel Benson, Jubilee Tan, Dinesh Rakheja, Carolina B. Livi, Eun-Hee Shim
Supplementary Figure 2. HK-2 and HEK293 cells were transiently cotransfected with the indicated siRNA and TET1 cDNA. Protein lysates were harvested and immunoblotted for the indicated proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620e56198e38862572feb4d6df9d4fdc
https://doi.org/10.1158/2159-8290.22530509.v1
https://doi.org/10.1158/2159-8290.22530509.v1
Autor:
Sunil Sudarshan, Karen Block, Shi Wei, Sejong Bae, Lining Guo, Teresa L. Johnson-Pais, Qiuhua Li, Robert J. Mishur, Shane L. Rea, Balachandra Chenna, Shilpa Dutta, Sadanan Velu, Richard Kirkman, Arindam P. Ghosh, Eun-Young Kho, Vishwas Parekh, Daniel Benson, Jubilee Tan, Dinesh Rakheja, Carolina B. Livi, Eun-Hee Shim
Supplementary Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ead0c4b3d1acc5443bb885ed733849
https://doi.org/10.1158/2159-8290.22530503.v1
https://doi.org/10.1158/2159-8290.22530503.v1
Autor:
Sunil Sudarshan, Karen Block, Shi Wei, Sejong Bae, Lining Guo, Teresa L. Johnson-Pais, Qiuhua Li, Robert J. Mishur, Shane L. Rea, Balachandra Chenna, Shilpa Dutta, Sadanan Velu, Richard Kirkman, Arindam P. Ghosh, Eun-Young Kho, Vishwas Parekh, Daniel Benson, Jubilee Tan, Dinesh Rakheja, Carolina B. Livi, Eun-Hee Shim
Supplementary Table 1. Clinical Data on Tumor Samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148350230be45fe065faa29aca141189
https://doi.org/10.1158/2159-8290.22530500.v1
https://doi.org/10.1158/2159-8290.22530500.v1
Autor:
Sunil Sudarshan, Karen Block, Shi Wei, Sejong Bae, Lining Guo, Teresa L. Johnson-Pais, Qiuhua Li, Robert J. Mishur, Shane L. Rea, Balachandra Chenna, Shilpa Dutta, Sadanan Velu, Richard Kirkman, Arindam P. Ghosh, Eun-Young Kho, Vishwas Parekh, Daniel Benson, Jubilee Tan, Dinesh Rakheja, Carolina B. Livi, Eun-Hee Shim
Supplementary Figure 1. A498 cells were stable transduced with the indicated construct. Protein lysates were harvested and immunoblotted for the indicated proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee17d282f472f31b0a1acd8b5c19fc2
https://doi.org/10.1158/2159-8290.22530512.v1
https://doi.org/10.1158/2159-8290.22530512.v1
Autor:
Sunil Sudarshan, Karen Block, Shi Wei, Sejong Bae, Lining Guo, Teresa L. Johnson-Pais, Qiuhua Li, Robert J. Mishur, Shane L. Rea, Balachandra Chenna, Shilpa Dutta, Sadanan Velu, Richard Kirkman, Arindam P. Ghosh, Eun-Young Kho, Vishwas Parekh, Daniel Benson, Jubilee Tan, Dinesh Rakheja, Carolina B. Livi, Eun-Hee Shim
Supplementary Figure 3. HEK293 cells were transiently transfected with either CV or L2HGDH cDNA and TET1 cDNA. Protein lysates were harvested and immunoblotted for the indicated proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741360692289275d4bc3a015a80246ae
https://doi.org/10.1158/2159-8290.22530506.v1
https://doi.org/10.1158/2159-8290.22530506.v1
Autor:
Eun Young Kho, Sadanan Velu, Shane L. Rea, Jubilee Tan, Shilpa Dutta, Qiuhua Li, Carolina B. Livi, Lining Guo, Daniel Benson, Arindam P. Ghosh, Vishwas Parekh, Sejong Bae, Dinesh Rakheja, Robert J. Mishur, Eun Hee Shim, Teresa L. Johnson-Pais, Balachandra Chenna, Karen Block, Shi Wei, Richard Kirkman, Sunil Sudarshan
Publikováno v:
Cancer discovery. 4(11)
Through unbiased metabolomics, we identified elevations of the metabolite 2-hydroxyglutarate (2HG) in renal cell carcinoma (RCC). 2HG can inhibit 2-oxoglutaratre (2-OG)–dependent dioxygenases that mediate epigenetic events, including DNA and histon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cea0fb2f1c112c5f4ea6b05d42b5b76
https://pubmed.ncbi.nlm.nih.gov/25182153
https://pubmed.ncbi.nlm.nih.gov/25182153
Autor:
Sunil Sudarshan, Arindam P. Ghosh, Daniel Benson, Eun-Young Kho, Ross P. Holmes, Sejong Bae, Eun-Hee Shim, Shi Wei, Balachandra Chenna, Richard Kirkman, Sadanan Velu, Carolina B. Livi, Karen Block, Qiuhua Li, Shane L. Rea, John Knight, Dinesh Rakheja
Publikováno v:
Cancer Research. 74:LB-131
We undertook an unbiased metabolomics profile of clear cell renal cell carcinoma (ccRCC), the most common histological subtype, to gain deeper insight into the metabolic basis of this disease. Here, we demonstrate elevations of the metabolite 2-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e67dc92776169b3ff09a02ab9a791eef
https://doi.org/10.1158/1538-7445.am2014-lb-131
https://doi.org/10.1158/1538-7445.am2014-lb-131