Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Sadahiro Iwabuchi"'
Autor:
Miho Kurokawa, Takeshi Goya, Motoyuki Kohjima, Masatake Tanaka, Sadahiro Iwabuchi, Shigeyuki Shichino, Satoshi Ueha, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Shigeki Tashiro, Hideo Suzuki, Masaki Kato, Shinichi Hashimoto, Hideo Matsuda, Kouji Matsushima, Yoshihiro Ogawa
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Acute liver failure (ALF) is a life-threatening disorder that progresses from self-limiting acute liver injury (ALI). Microcirculatory disturbance characterized by sinusoidal hypercoagulation and subsequent massive hypoxic hepatoc
Externí odkaz:
https://doaj.org/article/f24b7de720914341bdd83383c484cd32
Autor:
Masaki Ibe, Shinobu Tamura, Hideki Kosako, Yusuke Yamashita, Masamichi Ishii, Masaoh Tanaka, Hiroyuki Mishima, Akira Kinoshita, Sadahiro Iwabuchi, Shuhei Morita, Ko-ichiro Yoshiura, Shinichi Hashimoto, Naoyuki Nakao, Shigeaki Inoue
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 40, Iss , Pp 101107- (2024)
Schwannomatosis (SWN) is a rare genetic condition characterized by the risk of developing multiple benign peripheral nerve sheath tumors; however, the risk of developing malignant tumors in patients with SWN remains unclear. This study described the
Externí odkaz:
https://doaj.org/article/d6bb4a2d41504e64bfdb214d0388fb23
Autor:
Yuta Doshida, Shinichi Hashimoto, Sadahiro Iwabuchi, Yuka Takino, Toshiyuki Ishiwata, Toshiro Aigaki, Akihito Ishigami
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Senescent cells are predicted to occur and increase in animal tissues with aging. However, senescent cells in the tissues of aged animals remain to be identified. We refer to the marker genes to identify senescent cells in tissues as “age-
Externí odkaz:
https://doaj.org/article/009d14185bfc41ad962180e357571467
Autor:
Kenzaburo Yamaji, Sadahiro Iwabuchi, Yuko Tokunaga, Shinichi Hashimoto, Daisuke Yamane, Sakiko Toyama, Risa Kono, Bouchra Kitab, Kyoko Tsukiyama-Kohara, Yosuke Osawa, Yukiko Hayashi, Tsunekazu Hishima, Chise Tateno, Kiminori Kimura, Takeshi Okanoue, Michinori Kohara
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115379- (2023)
Nonalcoholic steatohepatitis (NASH) is a progressive fibrotic disease associated with an increased risk of developing hepatocellular carcinoma; at present, no efficient therapeutic strategy has been established. Herein, we examined the efficacy of PR
Externí odkaz:
https://doaj.org/article/319cc373c79a45febd31419ed4174bdf
Autor:
Ying-Yi Li, Kazuyuki Kuroki, Tetsuro Shimakami, Kazuhisa Murai, Kazunori Kawaguchi, Takayoshi Shirasaki, Kouki Nio, Saiho Sugimoto, Tomoki Nishikawa, Hikari Okada, Noriaki Orita, Hideo Takayama, Ying Wang, Phuong Doan Thi Bich, Astuya Ishida, Sadahiro Iwabuchi, Shinichi Hashimoto, Takeshi Shimaoka, Noriko Tabata, Miho Watanabe-Takahashi, Kiyotaka Nishikawa, Hiroshi Yanagawa, Motoharu Seiki, Kouji Matsushima, Taro Yamashita, Shuichi Kaneko, Masao Honda
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 533-558 (2023)
Background & Aims: Hepatitis B virus (HBV) infection is difficult to cure owing to the persistence of covalently closed circular viral DNA (cccDNA). We performed single-cell transcriptome analysis of newly established HBV-positive and HBV-negative he
Externí odkaz:
https://doaj.org/article/5994dbd6cb574256b719639b085d8fe8
Autor:
Sakiko Toyama, Tomoko Honda, Sadahiro Iwabuchi, Shinichi Hashimoto, Kenzaburo Yamaji, Yuko Tokunaga, Yusuke Matsumoto, Hideya Kawaji, Takashi Miyazaki, Yoshiaki Kikkawa, Michinori Kohara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intranasal vaccines that elicit mucosal immunity are deemed effective against respiratory tract infections such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but their ability to induce humoral immunity characterized by immunoglobu
Externí odkaz:
https://doaj.org/article/36f123777df6497f99fe3e9525a11e9a
Autor:
Yiran Li, Satoshi Arai, Kumiko Kato, Sadahiro Iwabuchi, Noriyuki Iwabuchi, Natsumi Muto, Hideki Motobayashi, Shukuko Ebihara, Miyuki Tanaka, Shinichi Hashimoto
Publikováno v:
Nutrients, Vol 16, Iss 1, p 42 (2023)
The interaction between the gut microbiota and the host can influence the host’s immune system. Bifidobacterium, a commensal genus of gut bacteria, seems to have positive effects on host health. Our previous clinical research showed that B. longum
Externí odkaz:
https://doaj.org/article/29a81c9f669a468d9b7aa45a25317446
Autor:
Sadahiro Iwabuchi, Tomohide Tsukahara, Toshitugu Okayama, Masahiro Kitabatake, Hideki Motobayashi, Shigeyuki Shichino, Tadashi Imafuku, Kenzaburo Yamaji, Kyohei Miyamoto, Shinobu Tamura, Satoshi Ueha, Toshihiro Ito, Shin-ichi Murata, Toshikazu Kondo, Kazuho Ikeo, Yutaka Suzuki, Kouji Matsushima, Michinori Kohara, Toshihiko Torigoe, Hiroki Yamaue, Shinichi Hashimoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neutralizing antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being developed world over. We investigated the possibility of producing artificial antibodies from the formalin fixation and paraffin-embedding (FFP
Externí odkaz:
https://doaj.org/article/32149fe894984f60b5857c5a88f4c29c
Autor:
Sadahiro Iwabuchi, Kyohei Miyamoto, Mayuko Hatai, Yurina Mikasa, Masahiro Katsuda, Shin-ichi Murata, Toshikazu Kondo, Hiroki Yamaue, Shinichi Hashimoto
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Whereas the COVID-19 disease pathophysiology is under investigation, it is important to identify the pathways of viral transmission and inflammation from the pre-illness to the disease-onset stages. We analyzed five lung lobes from a patient with COV
Externí odkaz:
https://doaj.org/article/05d20b41db2d479f9ea7a674bff829c4
Autor:
Hideki Kosako, Yusuke Yamashita, Shuhei Morita, Sadahiro Iwabuchi, Shinichi Hashimoto, Taka-Aki Matsuoka, Takashi Sonoki, Shinobu Tamura
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16162 (2022)
Endoplasmic reticulum stress activates inositol-requiring enzyme 1α (IRE1α) and protein kinase, R-like endoplasmic reticulum kinase (PERK), the two principal regulators of the unfolded protein response (UPR). In multiple myeloma, adaptive IRE1α si
Externí odkaz:
https://doaj.org/article/3b1f5c35758346cb9bb002220929b851