Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sadaharu Kotani"'
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2687-2696 (2013)
Several studies have shown that housing conditions and environmental exposure to a series of stimuli lead to behavior improvement in several species. While more works have been focused on illustrating changes of the proteome and transcriptome followi
Externí odkaz:
https://doaj.org/article/53411cb52f6041078671c3add4bfd988
Publikováno v:
Epilepsy Research. 137:152-158
Purpose Status epilepticus (SE) causes irreversible neurodegeneration if not terminated quickly. Perampanel (PER), a potent AMPA receptor antagonist, has previously been shown to terminate seizures in the lithium-pilocarpine SE model. In the present
Autor:
Mai Ando, Sadaharu Kotani, Naoto Watanabe, Yukio Ishikawa, Kanta Horie, Tatsuto Fukushima, Yosuke Nakatani, Toshiki Mochizuki, Masae Yamamoto
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Sadaharu Kotani, Ishani Savant-Landry, Robert Lai, Johan Luthman, Edgar Schuck, Ziad Hussein, Mitsuhiro Ino, Min-Kun Chang, Jagadeesh Aluri
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
Chemico-Biological Interactions. 175:227-230
Donepezil hydrochloride is a potent and selective acetylcholinesterase inhibitor and has been treated for Alzheimer's disease, in which the cholinergic dysfunction is observed. Recently, the degeneration of medial septal cholinergic nuclei in adult r
Publikováno v:
European Journal of Neuroscience. 17:1445-1454
We investigated the trace eyeblink conditioning in decerebrate guinea pigs to elucidate the possible role of the cerebellum and brainstem in this hippocampus-dependent task. A 350-ms tone conditioned stimulus was paired with a 100-ms periorbital shoc
Autor:
Shigenori Kawahara, Satoshi Fukunaga, Kanako Takatsuki, Masayoshi Mishina, Hisashi Mori, Yutaka Kirino, Sadaharu Kotani
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience = The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(1):17-22
Mutant mice lacking the glutamate receptor subunit delta2 exhibit changes in the structure and function of the cerebellar cortex. The most prominent functional feature is a deficiency in the long-term depression (LTD) at parallel fiber-Purkinje cell
Publikováno v:
European Journal of Neuroscience. 15:1267-1270
A decerebrate guinea pig preparation was used to test the hypothesis that brainstem-cerebellar circuitry is sufficient for classical delay eyeblink conditioning. Delay conditioning was carried out using a tone conditioned stimulus (CS) paired with a
Autor:
Kanako Takatsuki, Shigenori Kawahara, Sadaharu Kotani, Hisashi Mori, Masayoshi Mishina, Yutaka Kirino
Publikováno v:
Journal of Biological Physics. 28:539-547
Cerebellar long-term depression (LTD) at the parallel fiber-Purkinje cell synapses has been proposed to be a neural substrate for classical eyeblink conditioning. Mutant mice lacking the glutamate receptor subunit δ2 (GluRδ2), in which the cerebell