Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Sadaaki IWANAGA"'
Autor:
Cho Yeow Koh, Sundramurthy Kumar, Maria Kazimirova, Patricia A Nuttall, Uvaraj P Radhakrishnan, Seongcheol Kim, Pudur Jagadeeswaran, Takayuki Imamura, Jun Mizuguchi, Sadaaki Iwanaga, Kunchithapadam Swaminathan, R Manjunatha Kini
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26367 (2011)
The inhibition of thrombin is one of the important treatments of pathological blood clot formation. Variegin, isolated from the tropical bont tick, is a novel molecule exhibiting a unique 'two-modes' inhibitory property on thrombin active site (compe
Externí odkaz:
https://doaj.org/article/e73db7aa93c64005baef3cd0a4351529
Autor:
Kunchithapadam Swaminathan, Sadaaki Iwanaga, Patricia A. Nuttall, Cho Yeow Koh, R. Manjunatha Kini, Janaki Krishnamoorthy Iyer, Jun Mizuguchi, Mark Y. Chan, Ladislav Roller, Chacko Jobichen, Mária Kazimírová
Publikováno v:
FASEB Journal. 31(7)
Tick saliva is a rich source of antihemostatic compounds. We amplified a cDNA from the salivary glands of the tropical bont tick (Amblyomma variegatum) using primers based on the variegin sequence, which we previously identified as a novel thrombin i
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 25:411-422
Autor:
Janaki Krishnamoorthy, Iyer, Cho Yeow, Koh, Maria, Kazimirova, Ladislav, Roller, Chacko, Jobichen, Kunchithapadam, Swaminathan, Jun, Mizuguchi, Sadaaki, Iwanaga, Patricia A, Nuttall, Mark Y, Chan, R Manjunatha, Kini
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(7)
Tick saliva is a rich source of antihemostatic compounds. We amplified a cDNA from the salivary glands of the tropical bont tick (
Autor:
Seongcheol Kim, Jun Mizuguchi, Kunchithapadam Swaminathan, Uvaraj P. Radhakrishnan, Patricia A. Nuttall, Pudur Jagadeeswaran, Takayuki Imamura, Sundramurthy Kumar, Mária Kazimírová, R. Manjunathan Kini, Sadaaki Iwanaga, Cho Yeow Koh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e26367 (2011)
PLoS ONE, Vol 6, Iss 10, p e26367 (2011)
The inhibition of thrombin is one of the important treatments of pathological blood clot formation. Variegin, isolated from the tropical bont tick, is a novel molecule exhibiting a unique 'two-modes' inhibitory property on thrombin active site (compe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760337528e28defdb72e4161ddb65d8f
https://ora.ox.ac.uk/objects/uuid:70bd1ceb-1cc8-4d8f-8056-1cbe4a318c54
https://ora.ox.ac.uk/objects/uuid:70bd1ceb-1cc8-4d8f-8056-1cbe4a318c54
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1824:164-176
Metalloproteinases are among the most abundant toxins in many Viperidae venoms. Snake venom metalloproteinases (SVMPs) are the primary factors responsible for hemorrhage and may also interfere with the hemostatic system, thus facilitating loss of blo
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 22:171-185
Autor:
Y. Mori, T. Nakashima, Shunji Natsuka, T. Hamuro, Sadaaki Iwanaga, Sumihiro Hase, T. Hamamoto
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:111-120
Summary. Background: Tissue factor pathway inhibitor (TFPI) is a physiological protease inhibitor that inhibits the initial reactions of the extrinsic blood coagulation pathway. Most TFPI in human plasma is associated with lipoproteins; however, the
Autor:
Tsutomu Hamuro, Sadaaki Iwanaga, Hiroshi Kido, Yujiro Asada, Kinta Hatakeyama, Youichi Kunori, Shintaro Kamei, Takashi Kamimura, Yuushi Okumura
Publikováno v:
FEBS Journal. 274:3065-3077
Tissue factor pathway inhibitor (TFPI) is a multivalent Kunitz-type protease inhibitor that primarily inhibits the extrinsic pathway of blood coagulation. It is synthesized by various cells and its expression level increases in inflammatory environme
Autor:
Sadaaki Iwanaga
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
A hemocyte lysate from horseshoe crab (Limulus) produced a gel, when exposed to Gram-negative bacterial endotoxins, lipopolysaccharides (LPS). This gelation reaction of the lysate, so-called Limulus test, has been widely employed as a simple and very