Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sachiyuki Hamano"'
Autor:
Nobuyuki Mori, Toshiyuki Matsuoka, Norio Minami, Isao Saito, Takashi Musha, Kazutoshi Miyake, Sachiyuki Hamano, Naoki Yoneda, Hiroki Ishihara, Masayuki Matsukura, Tadao Shoji, Osamu Hiroshima
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:213-218
A phenolic benzofuran derivative 1 was identified as an angiotensin II receptor antagonist by random screening. Structural modifications led to a novel series of N-(4-hydroxyphenylmethyl)benzimidazoles and imidazo[4,5-b]pyridines, some of which inhib
Autor:
Yasuhiro Kabasawa, Keiji Ishibashi, Fumihiro Ozaki, Sachiyuki Hamano, Megumi Ikemori, Masayuki Matsukura, Norio Minami
Publikováno v:
ChemInform. 24
Autor:
Kazutoshi Miyake, Isao Saito, Toshiyuki Matsuoka, Norio Minami, Masayuki Matsukura, Tadao Shoji, Nobuyuki Mori, Naoki Yoneda, Sachiyuki Hamano, Osamu Hiroshima, Hiroki Ishihara, Takashi Musha
Publikováno v:
ChemInform. 25
A phenolic benzofuran derivative 1 was identified as an angiotensin II receptor antagonist by random screening. Structural modifications led to a novel series of N-(4-hydroxyphenylmethyl)benzimidazoles and imidazo[4,5-b]pyridines, some of which inhib
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:921-926
Syntheses of [phenyl-14C]4′-[[1-[2-(6-Methyl-2-pyridyl)ethyl]-4-piperidyl]carbonyl]methanesulfon-anilide dihydrochloride dihydrate (1) (14C-E-4031) and its pyridylpropyl analogue (2), that are selective class III antiarrhythmic agents, are describe
Autor:
Toshihiko Naitoh, Tadanobu Takamura, Ken'ichi Nomoto, Yoshiharu Daiku, Hasegawa Takashi, Hitoshi Oinuma, Norio Minami, Sachiyuki Hamano, Hiroshi Kakisawa
Publikováno v:
Journal of medicinal chemistry. 34(7)
A novel series of 4-[N-methyl-N-[(E)-3-[4-(methylsulfonyl)phenyl]-2- propenoyl]amino]benzenesulfonamides has been prepared and evaluated as membrane-bound phospholipase A2 inhibitors. A structure-activity relationship study indicated that the optimum
Autor:
Motosuke Yamanaka, Kazutoshi Miyake, Hiroshi Katoh, Sachiyuki Hamano, Mitsumasa Shino, Ken'ichi Nomoto, Hitoshi Oinuma, Kohei Sawada
Publikováno v:
Journal of medicinal chemistry. 33(3)
Autor:
S. Suda, N. Yoneda, M. Yamanaka, T. Hoshiko, M. Saito, Mitsumasa Shino, Nobuyuki Mori, Sachiyuki Hamano, Hiroki Ishihara, Toshiyuki Matsuoka
Publikováno v:
European Journal of Pharmacology. 183:1049
Autor:
Nobuyuki Mori, Toshiyuki Matsuoka, Mitsumasa Shino, Hiroki Ishihara, Sachiyuki Hamano, T. Hoshiko, N. Yoneda
Publikováno v:
European Journal of Pharmacology. 183:1048
Publikováno v:
Japanese Journal of Pharmacology. 26:367-375
Effects of 4-7-exo-methylene-hexahydroisoindoline-ethyl-guanidine hemisulfate (No. 865-123), a new guanidine derivative, on adrenergic neurons and its local anesthetic activity were investigated in comparison with guanethidine. Both derivatives produ
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 14:191-195
14C-Labelled compound of antihypertensive 4-chloro-3-sulfamoyl-N-(3aα, 4α, 5, 6, 7α, 7aα -hexahydro-4, 7-methano-isoindolin-2-yl) -benzamide (IV) was synthesized for biotransformation studies in three steps with p-chlorobenzoic acid-carbonyl-14C