Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sachin P Gadani"'
Autor:
Sachin P Gadani, Saumitra Singh, Sophia Kim, Jingwen Hu, Matthew D Smith, Peter A Calabresi, Pavan Bhargava
Publikováno v:
eLife, Vol 12 (2024)
While modern high efficacy disease modifying therapies have revolutionized the treatment of relapsing-remitting multiple sclerosis, they are less effective at controlling progressive forms of the disease. Meningeal inflammation is a recognized risk f
Externí odkaz:
https://doaj.org/article/f0ee71fdb81b4bebb30286d645aad9af
Autor:
Sachin P. Gadani, Maria Reyes-Mantilla, Larissa Jank, Samantha Harris, Morgan Douglas, Matthew D. Smith, Peter A. Calabresi, Ellen M. Mowry, Kathryn C. Fitzgerald, Pavan Bhargava
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103636- (2021)
Background: Sphingosine-1-phosphate receptor (S1P) modulators and anti-CD20 therapies impair humoral responses to SARS-CoV-2 mRNA vaccines. Relatively few studies have assessed the impact of an array of disease modifying therapies (DMTs) for multiple
Externí odkaz:
https://doaj.org/article/c9007f0f052b4829be8d1ab5a3eb2a56
Autor:
Sachin P. Gadani, Francene Gayle, Phillip Jones, Phillipe Gailloud, Roland Faigle, Victor C. Urrutia
Publikováno v:
Cerebrovascular Diseases. 52:234-238
Mechanical thrombectomy (MT) is the standard of care for the treatment of acute ischemic stroke due to large vessel occlusion, but the capacity to deliver this treatment can be limited in less populous areas and island territories. Here, we describe
Publikováno v:
European Journal of Immunology.
Autor:
Sachin P. Gadani, Michael D. Kornberg
Publikováno v:
Science Translational Medicine. 14
DICAM, a trafficking molecule preferentially expressed by T H 17 cells, may be a therapeutic target for treating neuroinflammation (Charabati et al. ).
Autor:
Kathryn C. Fitzgerald, Larissa Jank, Ellen M. Mowry, Peter A. Calabresi, Sachin P. Gadani, Pavan Bhargava, Matthew D. Smith, Maria Reyes-Mantilla, Morgan Douglas, Samantha Harris
Publikováno v:
EBioMedicine, Vol 73, Iss, Pp 103636-(2021)
EBioMedicine
EBioMedicine
Background: Sphingosine-1-phosphate receptor (S1P) modulators and anti-CD20 therapies impair humoral responses to SARS-CoV-2 mRNA vaccines. Relatively few studies have assessed the impact of an array of disease modifying therapies (DMTs) for multiple
Publikováno v:
Neuroimmunology Reports. 1:100003
Background Onset of MOG-IgG associated disease (MOGAD) may often occur following an infectious prodrome. Case Report Herein we present a case of a man with latent syphilis who developed meningoencephalomyelitis shortly after initiation of treatment w
Publikováno v:
Nature Reviews Neuroscience. 18:375-384
The evolution of adaptive immunity provides enhanced defence against specific pathogens, as well as homeostatic immune surveillance of all tissues. Despite being ‘immune privileged’, the CNS uses the assistance of the immune system in physiologic
Publikováno v:
The Journal of Experimental Medicine
Immune responses to central nervous system (CNS) injuries are multifaceted, but their contributions are incompletely understood. Here, Gadani et al. describe type 2 innate lymphocytes as novel meningeal-resident cells, characterizing their transcript
Publikováno v:
Cureus
A pituitary mass is a rare and poorly understood complication of granulomatosis with polyangiitis (GPA). Here we describe the case of a young woman with GPA who presented with signs and symptoms initially suggestive of meningitis but was ultimately f