Výsledky vyhledávání - "Sachin Dattram Pawar"

Preparation and characterization of amoxapine- and naringin-loaded solid lipid nanoparticles: drug-release and molecular-docking studies

Autor: Sandeep Jat, Manini Bhatt, Sanjana Roychowdhury, Vaibhav A Dixit, Sachin Dattram Pawar, Hitesh Kulhari, Amit Alexander, Pramod Kumar

Publikováno v: Nanomedicine. 17:2133-2144

Aim: Amoxapine (AMX) has been reported to be metabolized by CYP3A4 and CYP2D6. Naringin (NG) has been reported to inhibit CYP enzymes. Therefore, the current work was designed to develop AMX solid lipid nanoparticles (AMX-SLNs) and NG-SLNs for better

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8db1857f61ffc451b05830aff6471f79
https://doi.org/10.2217/nnm-2022-0167

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Process development for the total synthesis of the novel drug metabolite Carboxy toremifene as a standard reference material along with characterization and purity assessment for the Antidoping quality Control Purposes

Autor: Gangasani Jagadeesh Kumar, Sachin Dattram Pawar, Swati Ramesh Pawar, Abraroddin Mumtajoddin Khatib, Anurag Saini, Pintu Das, Kalyan K. Sethi, Pullapanthula Radhakrishnanand, Upadhyayula Suryanarayana Murty, P. L. Sahu, Sachin Dubey, Kapendra Sahu, Awanish Upadhyay, Rajesh Kumar Kori, Pramod Kumar

Publikováno v: Drug Testing and Analysis. 14:2002-2006

Tamoxifen and toremifene are two selective estrogen receptor modulators (SERMs) commonly used to treat breast cancer in women. Toremifene is well-known as a triphenylethylene derivative. Carboxy toremifene is a common metabolite of toremifene and tam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4a3baa30ce757ee8b5383bec3d349b
https://doi.org/10.1002/dta.3387

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Amoxapine-Loaded Solid Lipid Nanoparticles with Superior Preclinical Pharmacokinetics for Better Brain Delivery: LC-MS/MS and GC-MS Analysis

Autor: Sachin Dattram Pawar, Komal Gawali, Hitesh Kulhari, Upadhyayula Suryanarayana Murty, Pramod Kumar

Publikováno v: ACS Chemical Neuroscience.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f215f4e3afd80fa3ccc741c9c060ac6
https://doi.org/10.1021/acschemneuro.2c00673

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Simultaneous Method Development and Validation of Anastrozole Along with Piperine: Degradation Studies and Degradants Characterization Using LC-QTOF-ESI-MS Along with In-silico ADMET Predictions

Autor: Pramod Kumar, K. Jony Susanna, Rahul Gajbhiye, Bhaskar Sarmah, Sachin Dattram Pawar, Pakhuri Mehta, Upadhyayula Suryanarayana Murty, V. Ravichandiran, Amit Alexander

Publikováno v: Current Drug Metabolism. 23:113-130

Background:: Anastrozole (ATZ) is a selective non-steroidal inhibitor widely used for the treatment of breast cancer in post-menopausal women. ATZ exerts its biological activity by inhibiting the enzyme aromatase, which is responsible for converting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0177a10e3d6b083972c38ebde769d3
https://doi.org/10.2174/1389200223666220215152606

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