Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sachiko Yoshikawa"'
Autor:
Takuya Iino, Manabu Nagao, Hidekazu Tanaka, Sachiko Yoshikawa, Junko Asakura, Makoto Nishimori, Masakazu Shinohara, Amane Harada, Shunsuke Watanabe, Tatsuro Ishida, Ken-ichi Hirata, Ryuji Toh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The pathophysiology of variant transthyretin (TTR) amyloidosis (ATTRv) is associated with destabilizing mutations in the TTR tetramer. However, why TTR with a wild-type genetic sequence misfolds and aggregates in wild-type transthyretin amyl
Externí odkaz:
https://doaj.org/article/0649b95f344746439c3c1bbcebaf3940
Autor:
Makoto Nishimori, Tomoyuki Honjo, Kenji Kaihotsu, Naohiko Sone, Sachiko Yoshikawa, Junichi Imanishi, Kazuhiko Nakayama, Noriaki Emoto, Masanori Iwahashi
Publikováno v:
Case Reports in Cardiology, Vol 2018 (2018)
Pulmonary arterial hypertension (PAH) is a rare complication of dasatinib that was approved as a first-line therapy for chronic myelocytic leukemia (CML). A 24-year-old man presenting dyspnea at rest and leg edema was admitted to our hospital. He had
Externí odkaz:
https://doaj.org/article/be1ae195cd80498b97c27f01b950c045
Autor:
Yutaro Seto, Manabu Nagao, Takuya Iino, Amane Harada, Katsuhiro Murakami, Keiko Miwa, Masakazu Shinohara, Makoto Nishimori, Sachiko Yoshikawa, Junko Asakura, Tomoo Fujioka, Tatsuro Ishida, Ken-ichi Hirata, Ryuji Toh
Publikováno v:
Journal of Applied Laboratory Medicine; Jul2024, Vol. 9 Issue 4, p728-740, 13p
Autor:
Sachiko Yoshikawa, Manabu Nagao, Ryuji Toh, Masakazu Shinohara, Takuya Iino, Yasuhiro Irino, Makoto Nishimori, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-Ichi Hirata
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 322:H749-H761
To our knowledge, this study is the first to demonstrate that increased GLS1 expression and subsequent activation of glutaminolysis are associated with exacerbation of cardiac hypertrophy and fibrosis. Inhibiting GLS1 antagonized the adverse cardiac
Autor:
Sachiko Yoshikawa, Seimi Satomi-Kobayashi, Iino Takuya, Masakazu Shinohara, Koichi Watanabe, Hidekazu Tanaka, Ryuji Toh, Ken-ichi Hirata, Manabu Nagao, Yasuhiro Irino, Tatsuro Ishida
Publikováno v:
Biochemical and Biophysical Research Communications. 534:687-693
Background Metabolic remodeling in cardiomyocytes is deeply associated with the pathogenesis of heart failure (HF). Glutaminolysis is an anaplerotic pathway that incorporates α-ketoglutarate (αKG) derived from glutamine into the tricarboxylic acid
Autor:
Kenji Kaihotsu, Kazuhiko Nakayama, Sachiko Yoshikawa, Noriaki Emoto, Naohiko Sone, Junichi Imanishi, Makoto Nishimori, Tomoyuki Honjo, Masanori Iwahashi
Publikováno v:
Case Reports in Cardiology
Case Reports in Cardiology, Vol 2018 (2018)
Case Reports in Cardiology, Vol 2018 (2018)
Pulmonary arterial hypertension (PAH) is a rare complication of dasatinib that was approved as a first-line therapy for chronic myelocytic leukemia (CML). A 24-year-old man presenting dyspnea at rest and leg edema was admitted to our hospital. He had
Autor:
Masahiro Motoki, Kohei Kamemura, Naohiko Sone, Michiko Iseri, Junichi Imanishi, Masanori Iwahashi, Sachiko Yoshikawa, Tomoyuki Honjo, Kenji Kaihotsu
Publikováno v:
Internal Medicine
Inferior vena cava (IVC) thrombosis is very rare, particularly in the absence of an apparent congenital caval abnormality or hypercoagulable state. We herein report an unusual case of a healthy and active 62-year-old male bodybuilder with a mass-like
Autor:
Sachiko Yoshikawa, Naohiko Sone, Junichi Imanishi, Kenji Kaihotsu, Tomoyuki Honjo, Masanori Iwahashi, Makoto Nishimori
Publikováno v:
The international journal of cardiovascular imaging. 34(2)
Although acute pulmonary edema (APE) is common in patients with heart failure (HF) with preserved ejection fraction (EF), its pathogenesis in patients with HF with reduced EF (HFrEF) is not completely understood. The purpose of our study was to explo
Autor:
Yasuhide Mochizuki, Jun Mukai, Fumitaka Soga, Makiko Suzuki, Ken-ichi Hirata, Shun Yokota, Nao Shibata, Keiko Sumimoto, Kensuke Matsumoto, Eriko Hisamatsu, Keiko Hatazawa, Yusuke Tanaka, Hiroki Takada, Sachiko Yoshikawa, Kumiko Dokuni, Hidekazu Tanaka, Ayu Shono, Makiko Suto, Kentaro Yamashita
Publikováno v:
Journal of the American College of Cardiology. 73:764
Diabetes mellitus (DM) is a major cause of heart failure (HF) with preserved ejection fraction (HFpEF), usually presenting as left ventricular (LV) diastolic dysfunction. Thus, LV diastolic function should be considered a crucial marker of a preclini
Autor:
Koji Fukuzawa, Fumitaka Soga, Hidekazu Tanaka, Keiko Hatazawa, Shun Yokota, Ken-ichi Hirata, Sachiko Yoshikawa, Kumiko Dokuni, Kentaro Yamashita, Kensuke Matsumoto, Nao Shibata, Makiko Suto, Eriko Hisamatsu, Yasuhide Mochizuki, Keiko Sumimoto, Ayu Shono, Yusuke Tanaka, Makiko Suzuki, Hiroki Takada, Jun Mukai
Publikováno v:
Journal of the American College of Cardiology. 73:1505