Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sachiko Takebe"'
Publikováno v:
Eukaryotic Cell. 6:584-591
Plasmodium falciparum is the causative agent of severe human malaria, responsible for over 2 million deaths annually. Of the 5,300 polypeptides predicted to control the parasite life cycle in mosquitoes and humans, 60% are of unknown function. A majo
Publikováno v:
Structure. 13(2):213-223
SummaryTctex1 is a light chain found in both cytoplasmic and flagellar dyneins and is involved in many fundamental cellular activities, including rhodopsin transport within photoreceptors, and may function in the non-Mendelian transmission of t haplo
Publikováno v:
Molecular Biology of the Cell. 15:3891-3902
The radial spokes are required for Ca2+-initiated intraflagellar signaling, resulting in modulation of inner and outer arm dynein activity. However, the mechanochemical properties of this signaling pathway remain unknown. Here, we describe a novel nu
Autor:
Sachiko Takebe, Eric Dufour, Céline Plouffe, John S. Mort, Euridice Carmona, Robert Ménard, Patrizia Mason
Publikováno v:
Journal of Biological Chemistry. 273:4478-4484
The autocatalytic processing of procathepsin L was investigated in vitro using purified recombinant proenzyme expressed in Pichia pastoris. Pure intermolecular processing was studied by incubating the mutant procathepsin L (C25S), which cannot autoac
Publikováno v:
Eisei kagaku. 38:498-505
A chemical carcinogen, ethyl carbamate (urethane), has been shown to be a contaminant of various alcoholic beverages. The condition of ethyl carbamate formation from cyanide via cyanate and the method of its prevention method with a cyanide metaboliz
Publikováno v:
Chemical and Pharmaceutical Bulletin. 40:2764-2768
A series of dipeptidyl hydroxamic acids (H-X-Gly-NHOH: X = amino acid residues) was synthesized, and the inhibitory activity against Jack bean and Proteus mirabilis ureases [EC 3.5.1.5] was examined. A number of H-X-Gly-NHOH inhibited Jack bean ureas
Publikováno v:
Chemical and Pharmaceutical Bulletin. 39:980-985
We found a strong paraoxon-hydrolyzing activity (23.4 +/- 8.50 nmol/h/individual and 137 +/- 86.2 nmol/h/mg protein) in the crude extract from larvae of Culex tritaeniorhynchus Toyama 89, which is markedly resistant to organophosphorous insecticides.
Publikováno v:
Medical Entomology and Zoology. 42:33-42
Autor:
Choukri Ben Mamoun, April M. Bobenchik, Jeffrey C. Hoch, Dennis R. Voelker, Kamal El Bissati, Sachiko Takebe, Jennifer M. Reynolds, William H. Witola, Jae-Yeon Choi
Publikováno v:
The Journal of biological chemistry. 283(12)
The PfPMT enzyme of Plasmodium falciparum, the agent of severe human malaria, is a member of a large family of known and predicted phosphoethanolamine methyltransferases (PMTs) recently identified in plants, worms, and protozoa. Functional studies in
Autor:
René Coulombe, Yunge Li, Sachiko Takebe, Robert Ménard, Patrizia Mason, John S. Mort, Miroslaw Cygler
Publikováno v:
Proteins: Structure, Function, and Genetics. 25:398-400