Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Sachiko Oh-ishi"'
Autor:
Akinori Ueno, Sachiko Oh-ishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 1, Pp 1-20 (2003)
ABSTRACT: Roles for the kallikrein-kinin system in inflammation have been investigated extensively, and many reviews on this topic have been published during the 50 years since the discovery of bradykinin in 1949. Recent progress in the field has bee
Externí odkaz:
https://doaj.org/article/21b308f4014b496f923389bbdbcc8850
Autor:
Akinori, Ueno, Sachiko, Oh-ishi
Publikováno v:
Current Drug Target -Inflammation & Allergy. 1:363-376
Searches for chemical mediators of inflammation underlying classical signs of inflammation i.e. heat, redness, swelling, and pain have been performed and various experimental models for evaluation of new agents to manage these inflammatory signs have
Autor:
Iku Utsunomiya, Koichi Yuki, Shiho Shinomiya, Shuichi Ohuchida, Hiroaki Naraba, Sachiko Oh-ishi, Akinori Ueno, Fumitaka Ushikubi, Takayuki Maruyama, Atsushi Ichikawa, Shuh Narumiya, Yukihiko Sugimoto
Publikováno v:
International Congress Series. 1233:479-484
We examined the roles of prostaglandin receptors regulating tumor necrosis factor-alpha (TNFα) and IL-10 production by zymosan-stimulated murine peritoneal macrophages. During the stimulation with zymosan for 5 h, the presence of PGE2 or carbacyclin
Autor:
Naomi Tago, Tadashi Tanabe, Hiroaki Naraba, Chieko Yokoyama, Makoto Murakami, Mai Fueki, Sachiko Oh-ishi, Ichiro Kudo
Publikováno v:
Journal of Biological Chemistry. 277:28601-28608
Membrane-associated prostaglandin (PG) E2 synthase (mPGES) is an inducible terminal enzyme in the biosynthetic pathway for prostaglandin E2, which participates in many biological processes. In this study, we investigated the molecular mechanism contr
Autor:
Sachiko Oh-ishi, Eriha Dekura, Fumiaki Kojima, Mineka Yoshimura, Hiroaki Naraba, Yae Kosugi, Akinori Ueno
Publikováno v:
Biochemical Pharmacology. 63:2043-2053
We detected the expression of inducible bradykinin (BK) B 1 receptor mRNA in the rat ileum by the reverse transcriptase–polymerase chain reaction (RT–PCR) method, when the isolated ileum was suspended for at least 1 hr in an aerated Tyrode’s so
Autor:
Sachiko Oh-ishi, Akinori Ueno
Publikováno v:
Folia Pharmacologica Japonica. 117:255-261
It is known that prostaglandins (PGs) modify the inflammatory reaction in concert with other biologically active mediators. However, characteristics of these interactions or modulating actions have not yet been clarified well. Recently, the productio
Autor:
Yuri Ikeda, Fumitaka Ushikubi, Akinori Ueno, Shuh Narumiya, Sachiko Oh-ishi, Hiroaki Naraba, Takahiko Murata
Publikováno v:
Life Sciences. 66:PL155-PL160
To prove that prostaglandin I2 (PGI2) is a major prostaglandin involved in bradykinin-induced exudation, we examined carrageenin- or bradykinin-induced paw edema in prostacyclin receptor-deficient mice (IPKO). Paw volume of wild-type mice (IPWT) incr
Autor:
Sachiko Oh-ishi
Publikováno v:
YAKUGAKU ZASSHI. 120:455-462
Inflammatory signs, such as heat, redness, swelling and pain, have been described from the Greek era. In these phenomena various endogenous active substances, i.e., inflammatory mediators, could cause and manifest vascular dilatation, a vascular perm
Publikováno v:
Japanese Journal of Pharmacology. 84:140-145
Murine neuroblastoma cell line Neuro-2A cells and rat brain astrocytes showed a dose-dependent increase in intracellular Ca2+ in response to bradykinin, when assessed by a single cell image analyzing system. The Ca2+ increase in Neuro-2A cells by bra
Autor:
Paul N. Schofield, Izuho Hatada, Eamonn R. Maher, Wolf Reik, Dian Donnai, Tsunehiro Mukai, Johanna A. Joyce, Sachiko Oh-ishi, Wayne W K Lam, Trevor Cole
Publikováno v:
Journal of Medical Genetics. 36:518-523
Beckwith-Wiedemann syndrome (BWS) is a human imprinting disorder with a variable phenotype. The major features are anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less fr