Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Sachiko Miyagawa-Tomita"'
Autor:
Kaoru Mizukami, Hiroki Higashiyama, Yuichiro Arima, Koji Ando, Norihiro Okada, Katsumi Kose, Shigehito Yamada, Jun K Takeuchi, Kazuko Koshiba-Takeuchi, Shigetomo Fukuhara, Sachiko Miyagawa-Tomita, Hiroki Kurihara
Publikováno v:
eLife, Vol 12 (2023)
Coronary arteries are a critical part of the vascular system and provide nourishment to the heart. In humans, even minor defects in coronary arteries can be lethal, emphasizing their importance for survival. However, some teleosts survive without cor
Externí odkaz:
https://doaj.org/article/60a748bcac7443c98b59b981b8892e56
Autor:
Kazuaki Maruyama, Sachiko Miyagawa-Tomita, Yuka Haneda, Mayuko Kida, Fumio Matsuzaki, Kyoko Imanaka-Yoshida, Hiroki Kurihara
Publikováno v:
eLife, Vol 11 (2022)
Lymphatic vessels are crucial for tissue homeostasis and immune responses in vertebrates. Recent studies have demonstrated that lymphatic endothelial cells (LECs) arise from both venous sprouting (lymphangiogenesis) and de novo production from non-ve
Externí odkaz:
https://doaj.org/article/18d6a1abc80d404abe2d29fedf9a5939
Autor:
Kazuaki Maruyama, Kazuaki Naemura, Kenji Yoshihara, Kyoko Imanaka-Yoshida, Hiroki Kurihara, Sachiko Miyagawa-Tomita
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100775- (2021)
Summary: Myocardial infarction (MI) is one of the most common causes of death worldwide. Animal models for MI are useful for studying the pathophysiology and developing therapies. Here, we describe a surgical protocol for permanent ligation of the le
Externí odkaz:
https://doaj.org/article/8deb3570fc86481aaf3a0fddee3f07f5
Autor:
Kazuaki Maruyama, Kazuaki Naemura, Yuichiro Arima, Yasunobu Uchijima, Hiroaki Nagao, Kenji Yoshihara, Manvendra K. Singh, Akiyoshi Uemura, Fumio Matsuzaki, Yutaka Yoshida, Yukiko Kurihara, Sachiko Miyagawa-Tomita, Hiroki Kurihara
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102305- (2021)
Summary: Blood and lymphatic vessels surrounding the heart develop through orchestrated processes from cells of different origins. In particular, cells around the outflow tract which constitute a primordial transient vasculature, referred to as aorti
Externí odkaz:
https://doaj.org/article/b38903fdfe96445f8df53c27264b41b4
Autor:
Shingo Takahara, Shin-ichi Inoue, Sachiko Miyagawa-Tomita, Katsuhisa Matsuura, Yasumi Nakashima, Tetsuya Niihori, Yoichi Matsubara, Yoshikatsu Saiki, Yoko Aoki
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 43-53 (2019)
Background: Noonan syndrome (NS) is a genetic disorder characterized by short stature, a distinctive facial appearance, and heart defects. We recently discovered a novel NS gene, RIT1, which is a member of the RAS subfamily of small GTPases. NS patie
Externí odkaz:
https://doaj.org/article/41e0ef09b0594ee6b55ce28a69a4c23e
Autor:
Yasuhiro Kazuki, Feng J Gao, Yicong Li, Anna J Moyer, Benjamin Devenney, Kei Hiramatsu, Sachiko Miyagawa-Tomita, Satoshi Abe, Kanako Kazuki, Naoyo Kajitani, Narumi Uno, Shoko Takehara, Masato Takiguchi, Miho Yamakawa, Atsushi Hasegawa, Ritsuko Shimizu, Satoko Matsukura, Naohiro Noda, Narumi Ogonuki, Kimiko Inoue, Shogo Matoba, Atsuo Ogura, Liliana D Florea, Alena Savonenko, Meifang Xiao, Dan Wu, Denise AS Batista, Junhua Yang, Zhaozhu Qiu, Nandini Singh, Joan T Richtsmeier, Takashi Takeuchi, Mitsuo Oshimura, Roger H Reeves
Publikováno v:
eLife, Vol 9 (2020)
Animal models of Down syndrome (DS), trisomic for human chromosome 21 (HSA21) genes or orthologs, provide insights into better understanding and treatment options. The only existing transchromosomic (Tc) mouse DS model, Tc1, carries a HSA21 with over
Externí odkaz:
https://doaj.org/article/902bee1fcc954ec09607d3e505b90a1b
Autor:
Daiju Oba, Shin-ichi Inoue, Sachiko Miyagawa-Tomita, Yasumi Nakashima, Tetsuya Niihori, Seiji Yamaguchi, Yoichi Matsubara, Yoko Aoki
Publikováno v:
EBioMedicine, Vol 27, Iss C, Pp 138-150 (2018)
Costello syndrome is a “RASopathy” that is characterized by growth retardation, dysmorphic facial appearance, hypertrophic cardiomyopathy and tumor predisposition. >80% of patients with Costello syndrome harbor a heterozygous germline G12S mutati
Externí odkaz:
https://doaj.org/article/d07a04a64cc0409ba7327db6d8df0897
Autor:
Rieko Asai, Yuka Haneda, Daiki Seya, Yuichiro Arima, Kimiko Fukuda, Yukiko Kurihara, Sachiko Miyagawa-Tomita, Hiroki Kurihara
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The somatopleure is the amniotic primordium in amniote development, but its boundary to the embryonic body at early embryonic stages and the fate of cells constituting this structure are not well characterized. It also remains unclear how ce
Externí odkaz:
https://doaj.org/article/0045064f78ab43f3986fcd8c196fb58a
Autor:
Kazuki Kodo, Shinsuke Shibata, Sachiko Miyagawa-Tomita, Sang-Ging Ong, Hiroshi Takahashi, Tsutomu Kume, Hideyuki Okano, Rumiko Matsuoka, Hiroyuki Yamagishi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The cardiac neural crest cells (cNCCs) and the second heart field (SHF) play key roles in development of the cardiac outflow tract (OFT) for establishment of completely separated pulmonary and systemic circulations in vertebrates. A neurovas
Externí odkaz:
https://doaj.org/article/13a01baded6f471487968b40ed5721d1