Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sachiko Iwaki"'
Autor:
Takahiro Yasumi, Ryuta Nishikomori, Osamu Ohara, Yusuke Kawashima, Tomohiro Morio, Kosaku Murakami, Syuji Takei, Tomohiro Kubota, Toshio Heike, Makio Takahashi, Hirokazu Kanegane, Hidetoshi Takada, Masahiko Isa-Nishitani, Atsushi Hijikata, Moeko Ito, Takeshi Shiba, Shunsuke Kajikawa, Tadateru Yasu, Naoko Nakano, Shouichi Ohga, Tsubasa Okano, Hiroaki Umebayashi, Junko Takita, Yoshinori Hasegawa, Dai Keino, Sachiko Iwaki-Egawa, Etsuro Nanishi, Hiroshi Nihira, Kazushi Izawa, Yoji Sasahara, Yoshitaka Honda
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:550-562
Background Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive inflammatory disease caused by loss-of-function mutations in both alleles of the ADA2 gene. Most patients with DADA2 exhibit systemic vasculopathy consistent with polyar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14703269403da3dab5878aad5c028748
https://doi.org/10.1016/j.jaci.2021.01.018
https://doi.org/10.1016/j.jaci.2021.01.018
Publikováno v:
Biochimica et biophysica acta. General subjects. 1866(12)
Adenosine deaminase 2 (ADA2) regulates extracellular levels of adenosine and the optimal expression of ADA2 is essential for modulating the immune system. However, the mechanisms regulating the production of active ADA2 enzyme are not fully understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86938d3167dbfb8b2a18cb2754d11c48
https://pubmed.ncbi.nlm.nih.gov/36029899
https://pubmed.ncbi.nlm.nih.gov/36029899
Autor:
Dai Keino, Kensuke Kondoh, Yuhwa Kim, Akina Sudo, Ryo Ohyama, Mizuho Morimoto, Hiroshi Nihira, Kazushi Izawa, Sachiko Iwaki Egawa, Tetsuya Mori, Akitoshi Kinoshita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c02984eea5c07f331f1c1224b552c8bd
https://doi.org/10.22541/au.158888238.86928045
https://doi.org/10.22541/au.158888238.86928045
Publikováno v:
Intractable & Rare Diseases Research. 7:229-235
A series of our "inflammageing" study examining serum samples from a maximum of 217 healthy Japanese individuals aged between 1 and 100 years and mutation-proven 40 patients with Werner syndrome (WS) indicated normal aging-associated elevations of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f62a9c075c3a16bc07c2970cce8249
https://doi.org/10.5582/irdr.2018.01092
https://doi.org/10.5582/irdr.2018.01092
Autor:
Moeko Ito, Kazushi Izawa, Sachiko Iwaki-Egawa, Hiroshi Nihira, Takahiro Yasumi, Ryuta Nishikomori
Publikováno v:
Analytical Biochemistry. 628:114292
Background Deficiency of adenosine deaminase 2 (DADA2) is an autoinflammatory disease caused by mutations in the adenosine deaminase 2 (ADA2) gene. Loss of functional ADA2 activity results in vasculitis syndrome, immunodeficiency, and hematopoietic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ac9038525f5c3da3b8b472cd57b0f9
https://doi.org/10.1016/j.ab.2021.114292
https://doi.org/10.1016/j.ab.2021.114292
Age-associated minor inflammation: inflammageing may explain human ageing mechanism(s). Our previous study reported a significant increase in the serum level of highly sensitive C-reactive protein (hsCRP) with normal ageing and the patients with Wern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b69f2258db958aa3ccb7675b600471d
https://europepmc.org/articles/PMC4869575/
https://europepmc.org/articles/PMC4869575/
Autor:
Masanobu Sugimoto, Yasuhiro Furuichi, Masaaki Matsuura, Kazunori Sugimoto, Yasuhiro Watanabe, Yuichi Ishikawa, Tetsuhito Ogino, Sachiko Iwaki-Egawa, Makoto Goto, Seigaku Hayashi
Publikováno v:
Experimental Gerontology. 47:936-939
Minor inflammation-driven aging (inflammaging) has been proposed to explain human aging mechanism. To study the inflammatory condition associated with normal human aging, highly sensitive CRP (hsCRP) was examined in the sera collected from 217 health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211b08cc7e55ac6c4844d9aeb541ceaa
https://doi.org/10.1016/j.exger.2012.08.010
https://doi.org/10.1016/j.exger.2012.08.010
Autor:
Sachiko Iwaki-Egawa, Chinami Suzuki, Makoto Yamamoto, Kazuya Hiura, Yasuhiro Watanabe, Kei Takamura, Akiko Shiraishi, Hitoshi Komori
Publikováno v:
Cancer biomarkers : section A of Disease markers. 15(4)
BACKGROUND: Bevacizumab is a recombinant humanized monoclonal antibody against vascular endothelial growth factor (VEGF), which is a key regulator of tumor angiogenesis. OBJECTIVE: To evaluate biomarkers to predict the benefit of paclitaxel and carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5842a49441ef74665c41ba561c758e8
https://pubmed.ncbi.nlm.nih.gov/25835177
https://pubmed.ncbi.nlm.nih.gov/25835177
Autor:
Kentaro Suzuki, Tadashi Sugawara, Yoshiyuki Kageyama, Sachiko Iwaki, Yuta Kurokome, Naruho Tanigake, Sadamu Takeda
Publikováno v:
Chemical communications. 49(82):9386-9388
Submillimetre size self-assemblies composed of oleate and azobenzene derivatives show forceful motions such as screw-type coiling–recoiling motion by photoirradiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47738019aa4b66b2434c140d92e448fe
http://hdl.handle.net/2115/57294
http://hdl.handle.net/2115/57294
Publikováno v:
Journal of Biochemistry. 124:428-433
Dipeptidyl peptidase IV (DPP IV) in normal human serum was purified 14,400-fold with a 25% yield to homogeneity. The molecular weight of the purified enzyme was approximately 110,000 on SDS-PAGE, almost the same as that of human kidney membrane-bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4061939e8df4663b9a3b9a44d894f7
https://doi.org/10.1093/oxfordjournals.jbchem.a022130
https://doi.org/10.1093/oxfordjournals.jbchem.a022130