Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Sachiko, Watanabe"'
Autor:
Satoshi Ikeda, Kazuo Hasegawa, Kenta Kachi, Akihiro Yanagisawa, Sachiko Kawakami, Shinsuke Hamasaki, Sachiko Watanabe, Aki Yoshikawa, Takayuki Takahama, Kazuhiko Nakagawa
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Background Previous reports indicated still low implementation rates of multigene testing for advanced non‐small cell lung cancer (NSCLC) in Japan. Methods This is a retrospective study launched at the initiative of lung cancer patients. P
Externí odkaz:
https://doaj.org/article/e197cdaf76fd4e8d825004f842e54426
Autor:
Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Emi Aizawa, Yoshiko Mizushina, Sachiko Watanabe, Chintogtokh Baatarjav, Takayoshi Matsumura, Masafumi Takahashi
Publikováno v:
eLife, Vol 11 (2022)
Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory syndrome caused by mutations of NLRP3 gene encoding cryopyrin. Familial cold autoinflammatory syndrome, the mildest form of CAPS, is characterized by cold-induced inflammation induc
Externí odkaz:
https://doaj.org/article/54eab856f68542b9915d303cd6a17e23
Autor:
Naoya Yamada, Tadayoshi Karasawa, Hiroaki Kimura, Sachiko Watanabe, Takanori Komada, Ryo Kamata, Ariunaa Sampilvanjil, Junya Ito, Kiyotaka Nakagawa, Hiroshi Kuwata, Shuntaro Hara, Koichi Mizuta, Yasunaru Sakuma, Naohiro Sata, Masafumi Takahashi
Publikováno v:
Cell Death and Disease, Vol 11, Iss 2, Pp 1-16 (2020)
Abstract Acetaminophen (APAP) overdose is a common cause of drug-induced acute liver failure. Although hepatocyte cell death is considered to be the critical event in APAP-induced hepatotoxicity, the underlying mechanism remains unclear. Ferroptosis
Externí odkaz:
https://doaj.org/article/4c3e813c18814f5e811902c02c3b7717
Autor:
Shin-ichirou Syobu, Sachiko Watanabe
Publikováno v:
Horticulturae, Vol 8, Iss 7, p 578 (2022)
In 2016, an onion downy mildew epidemic caused by Peronospora destructor severely damaged the commercial onion fields in Saga Prefecture, western Japan. To identify the factors underlying the outbreak, we investigated the symptoms of downy mildew cau
Externí odkaz:
https://doaj.org/article/13c6bb3622e04409973e2363969171ff
Publikováno v:
The Journal of Immunology. 210:1386-1395
LPS interacts with TLR4, which play important roles in host-against-pathogen immune responses, by binding to MD-2 and inducing an inflammatory response. In this study, to our knowledge, we found a novel function of lipoteichoic acid (LTA), a TLR2 lig
Autor:
Emi Aizawa, Tadayoshi Karasawa, Sachiko Watanabe, Takanori Komada, Hiroaki Kimura, Ryo Kamata, Homare Ito, Erika Hishida, Naoya Yamada, Tadashi Kasahara, Yoshiyuki Mori, Masafumi Takahashi
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Pyroptosis is a form of regulated cell death that is characterized by gasdermin processing and increased membrane permeability. Caspase-1 and caspase-11 have been considered to be essential for gasdermin D processing associated with inflamma
Externí odkaz:
https://doaj.org/article/b76dceaede2544eaac2ccc4136359c28
Autor:
Sachiko Watanabe, Shin‐ichirou Syobu
Publikováno v:
Journal of Phytopathology. 170:711-723
Autor:
Motoi Kobayashi, Fumitake Usui-Kawanishi, Tadayoshi Karasawa, Hiroaki Kimura, Sachiko Watanabe, Nathan Mise, Fujio Kayama, Tadashi Kasahara, Naoyuki Hasebe, Masafumi Takahashi
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176676 (2017)
Cardiac glycosides such as digoxin are Na+/K+-ATPase inhibitors that are widely used for the treatment of chronic heart failure and cardiac arrhythmias; however, recent epidemiological studies have suggested a relationship between digoxin treatment a
Externí odkaz:
https://doaj.org/article/76bcf39fe93f46578d83bb2f31eab493
Autor:
Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Emi Aizawa, Yoshiko Mizushina, Sachiko Watanabe, Chintogtokh Baatarjav, Takayoshi Matsumura, Masafumi Takahashi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978b7b5725be80402b9e14afb00f7a12
https://doi.org/10.7554/elife.75166.sa2
https://doi.org/10.7554/elife.75166.sa2
Autor:
Tadayoshi Karasawa, Fumitake Usui-Kawanishi, Sachiko Watanabe, Ryo Kamata, Takanori Komada, Masafumi Takahashi, Tsukasa Ohmori, Naoya Yamada, Hiroaki Kimura, Katsuya Dezaki
Publikováno v:
Biochemical and Biophysical Research Communications. 531:125-132
Background Platelets are critical mediators of vascular homeostasis and thrombosis, and also contribute to the development of inflammation. NLRP3 inflammasome is a cytosolic multi-protein complex that consists of NLRP3, ASC and caspase-1, and regulat