Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sachiko, Shinoda"'
Autor:
Mark Dunleavy, Claire Ewart, Christian Kerskens, Ross D. Dolan, David C. Henshall, Clara K. Schindler, Sachiko Shinoda, Oliviero L. Gobbo
Publikováno v:
The American Journal of Pathology. 176:330-342
Hippocampal sclerosis is a common pathological finding in patients with temporal lobe epilepsy, including children, but a causal relationship to early-life seizures remains in question. Neonatal status epilepticus in animals can result in neuronal de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bef22e25038e69189a70d3293f5d02e
https://doi.org/10.2353/ajpath.2010.090119
https://doi.org/10.2353/ajpath.2010.090119
Autor:
Waro Taki, Clara K. Schindler, Roger P. Simon, Sachiko Shinoda, Tomohiro Araki, Jing-Quan Lan, David C. Henshall
Publikováno v:
Journal of Neuroscience Research. 76:121-128
Although mice are amenable to gene knockout, they have not been exploited in the setting of seizure-induced neurodegeneration due to the resistance to injury of key mouse strains. We refined and developed models of seizure-induced neuronal death in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58823cfd15395dcaaa499557ab77d6f7
https://doi.org/10.1002/jnr.20064
https://doi.org/10.1002/jnr.20064
Autor:
Sachiko Shinoda, Waro Taki, Roger P. Simon, Clara K. Schindler, David C. Henshall, Julie A. Saugstad, Jing Quan-Lan
Publikováno v:
Journal of Neurochemistry. 86:460-469
Seizure-induced neuronal death may involve coordinated intracellular trafficking and protein–protein interactions of members of the Bcl-2 family. The 14-3-3 proteins are known to sequester certain pro-apoptotic members of this family. BH3-interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0e2b5219241199c3821de8de3bf6cf0
https://doi.org/10.1046/j.1471-4159.2003.01860.x
https://doi.org/10.1046/j.1471-4159.2003.01860.x
Autor:
Clara K. Schindler, Roger P. Simon, Sachiko Shinoda, David C. Henshall, Tomohiro Araki, Jing-Quan Lan
Publikováno v:
Journal of Neurochemistry. 86:1260-1270
Death-associated protein (DAP) kinase is calcium-regulated and known to function downstream of death receptors, prompting us to examine its role in the mechanism of seizure-induced neuronal death. Brief seizures were focally evoked in rats, eliciting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1da99837456685845574d7ee8be0f698
https://doi.org/10.1046/j.1471-4159.2003.01934.x
https://doi.org/10.1046/j.1471-4159.2003.01934.x
Autor:
Jing-Quan Lan, Robert Meller, Clara K. Schindler, Roger P. Simon, David C. Henshall, Sachiko Shinoda, Tomohiro Araki, Shana L. Skradski, Waro Taki
Publikováno v:
European Journal of Neuroscience. 17:2065-2076
The consequences of activation of tumour necrosis factor receptor 1 (TNFR1) during neuronal injury remain controversial. The apoptosis signal-regulating kinase 1 (ASK1), a mitogen-activated protein kinase kinase kinase, can mediate cell death downstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e24591f619b42485902ac0e585a6ec8
https://doi.org/10.1046/j.1460-9568.2003.02655.x
https://doi.org/10.1046/j.1460-9568.2003.02655.x
Publikováno v:
International journal of physiology, pathophysiology and pharmacology. 6(4)
Status epilepticus in the adult brain invariably causes an increase in hippocampal neurogenesis and the appearance of ectopic cells and this has been implicated as a causal factor in epileptogenesis. The effect of status epilepticus on neurogenesis i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebb04a3d77c989495e6ba726250b997c
https://pubmed.ncbi.nlm.nih.gov/25755841
https://pubmed.ncbi.nlm.nih.gov/25755841
Autor:
Ina Koegel, Weizhen Wang, Roger P. Simon, David C. Henshall, Akitaka Yamamoto, Seiji Hatazaki, Sachiko Shinoda, Mark Dunleavy, Zhi-Gang Xiong, Patrick Dicker, Xiang-Ping Chu, Brona M. Murphy, Robert Meller, Clara K. Schindler, Jochen H. M. Prehn, Carmen Bellver-Estelles
Publikováno v:
The American journal of pathology. 171(4)
Experimentally evoked seizures can activate the intrinsic mitochondrial cell death pathway, components of which are modulated in the hippocampus of patients with temporal lobe epilepsy. Bcl-2 family proteins are critical regulators of mitochondrial d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf598bbaa7ac83144015414ef9ffdbe7
https://pubmed.ncbi.nlm.nih.gov/17702891
https://pubmed.ncbi.nlm.nih.gov/17702891
Autor:
David C. Henshall, Tomohiro Araki, Sachiko Shinoda, Waro Taki, Roger P. Simon, Robert Meller, Clara K. Schindler, Jing Quan-Lan
Publikováno v:
Hippocampus. 14(3)
Death-associated protein (DAP) kinase is a novel regulator of cell death whose in vivo target(s) and role in neuronal cell death remain uncertain. Since DAP kinase has been implicated in p53-mediated apoptosis, a pathway activated following epileptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e44031561717f587f9b987b6bb8a22
https://pubmed.ncbi.nlm.nih.gov/15132432
https://pubmed.ncbi.nlm.nih.gov/15132432
Publikováno v:
Neuroscience letters. 356(3)
The molecular regulation of seizure-induced neuronal death may involve interactions between proteins of the Bcl-2 and 14-3-3 families. To further examine these pathways we performed subcellular fractionation on hippocampi obtained following a brief p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca8e95090242e169340640c661c8287
https://pubmed.ncbi.nlm.nih.gov/15036620
https://pubmed.ncbi.nlm.nih.gov/15036620
Autor:
David C, Henshall, Tomohiro, Araki, Clara K, Schindler, Sachiko, Shinoda, Jing-Quan, Lan, Roger P, Simon
Publikováno v:
Journal of neurochemistry. 86(5)
Death-associated protein (DAP) kinase is calcium-regulated and known to function downstream of death receptors, prompting us to examine its role in the mechanism of seizure-induced neuronal death. Brief seizures were focally evoked in rats, eliciting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::baff87220991e2f1ef4626e2a09afe3d
https://pubmed.ncbi.nlm.nih.gov/12911633
https://pubmed.ncbi.nlm.nih.gov/12911633