Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sachi Hoshi"'
Regulation of Vascular Smooth Muscle Cell Proliferation by Nuclear Factor-κB and Its Inhibitor, I-κB
Publikováno v:
Journal of Biological Chemistry. 275:883-889
Proliferation of vascular smooth muscle cells (SMC) is a crucial event in the formation of atherosclerotic tissues and is regulated by nuclear transcriptional factors including nuclear factor-kappaB (NF-kappaB). We constructed a reporter gene assay t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfed73c2ff2e439b9cf2838cd3d94295
https://doi.org/10.1074/jbc.275.2.883
https://doi.org/10.1074/jbc.275.2.883
Publikováno v:
The American Journal of Pathology. 153:1511-1520
Mature podocytes are regarded as growth-arrested cells with characteristic phenotypic features that underlie their function. To determine the relationship between cell cycle regulation and differentiation, the spatiotemporal expression of cyclin A, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a332f59724f72b657d3b8c67dc0507
https://doi.org/10.1016/s0002-9440(10)65739-2
https://doi.org/10.1016/s0002-9440(10)65739-2
Autor:
Tomoyuki Tagi, Issei Imoto, Fumie Kisumi-Hayashi, Toshiya Ochiai, Eigo Otsuji, Shojiro Kikuchi, Yoko Kinoshita-Ida, Toshio Imai, Yukihito Kokuba, Johji Inazawa, Takeshi Matsui, Sachi Hoshi, Koji Morimoto
Publikováno v:
Journal of gastroenterology. 45(12)
Colorectal cancer is a common disease that is usually detected at an advanced stage, because early-stage cancer is mostly asymptomatic and appropriate serologic biomarkers have not been established. We have previously identified dermokine (DK) as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebf3594bd3602a71552f954c8a28106
https://pubmed.ncbi.nlm.nih.gov/20652332
https://pubmed.ncbi.nlm.nih.gov/20652332
Autor:
Yujing Shu, Michio Nagata, Shinsuke Tomari, Keiko Nakayama, Hiroyasu Nagahama, Keiichi I. Nakayama, Sachi Hoshi
Publikováno v:
Anatomy and embryology. 206(1-2)
The cell cycle inhibitors p27 and p57 are initially concurrently expressed at a critical point of glomerulogenesis and podocyte differentiation. The present study generated mice lacking both p27 and p57, in order to investigate the synergistic roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea97d778ed56d6af4f88dce4fbe1804
https://pubmed.ncbi.nlm.nih.gov/12478365
https://pubmed.ncbi.nlm.nih.gov/12478365
Publikováno v:
Pathology international. 52(3)
Tubular response, including phenotypic changes against a variety of injuries, is an initial event that promotes tubulointerstitial injuries. Using the progressive kidney disease model of rat adriamycin (ADR) nephrosis, the present study focused on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2014baa363caa585d4a4eb9773f3f822
https://pubmed.ncbi.nlm.nih.gov/11972865
https://pubmed.ncbi.nlm.nih.gov/11972865
Autor:
Michio Nagata, Yujing Shu, Tomoko Inagaki, Sachi Hoshi, Jiro Sonoda, Fusayo Yoshida, Teruo Watanabe, Kenichi Nomoto
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 82(1)
The zucker diabetic fatty (ZDF-fa/fa) rat is one of the attractive models for type II diabetes based on impaired glucose tolerance caused by the inherited insulin-resistance gene fa. Characterization of nephropathy in this model may provide useful in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e88d9ca252e0f60a14e1b0098f661f5
https://pubmed.ncbi.nlm.nih.gov/11796823
https://pubmed.ncbi.nlm.nih.gov/11796823
Publikováno v:
Biochemical and biophysical research communications. 290(1)
Podocytes are the major site of vascular endothelial growth factor (VEGF) production in the kidney, and up-regulation of VEGF plays a critical role in the progression of diabetic nephropathy. Using a differentiated mouse podocyte cell line, we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846634d2f59a06397b566a9d3a665fdb
https://pubmed.ncbi.nlm.nih.gov/11779150
https://pubmed.ncbi.nlm.nih.gov/11779150
Autor:
Katsuji Nakamura, Tomohiro Matsushima, Akihiko Tsuruoka, Junji Matsui, Yuji Yamamoto, Zoltan Dezso, Kazuki Miyazaki, Fusayo Mimura, Hiroshi Obaishi, Taro Semba, Masayuki Matsukura, Yasuhiro Funahashi, Atsumi Yamaguchi, Toru Haneda, Kenichi Nomoto, Junichi Kamata, Toshiaki Wakabayashi, Makoto Asada, Kentaro Yoshimatsu, Tatsuo Watanabe, Keiko Takahashi, Yoshio Fukuda, Sachi Hoshi, Osamu Tohyama
Publikováno v:
Vascular Cell
Background Lenvatinib is an oral inhibitor of multiple receptor tyrosine kinases (RTKs) targeting vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet growth factor receptor α (PDGFR α), RET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc52d269e4d1d39f62b83903bdb70bf
https://doi.org/10.1186/2045-824x-6-18
https://doi.org/10.1186/2045-824x-6-18
Publikováno v:
Biochemical and biophysical research communications. 231(3)
Thrombopoietin (TPO) is a hemopoietic cytokine that specifically stimulates the growth and development of megakaryocytes. In addition to full-length TPO (corresponding to TPO-1), cDNAs of three truncated variants (TPO-2 to 4) have been isolated. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d2c8904c81430fb6759efe470ee3ce
https://pubmed.ncbi.nlm.nih.gov/9070902
https://pubmed.ncbi.nlm.nih.gov/9070902