Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sachi D. Dharia"'
Autor:
Jerry R. Mendell, Anne M. Connolly, Kelly J. Lehman, Danielle A. Griffin, Sohrab Z. Khan, Sachi D. Dharia, Lucía Quintana-Gallardo, Louise R. Rodino-Klapac
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 74-83 (2022)
Given the increasing number of gene transfer therapy studies either completed or underway, there is growing attention to the importance of preexisting adaptive immunity to the viral vectors used. The recombinant viral vectors developed for gene trans
Externí odkaz:
https://doaj.org/article/9eafd3b4081a49d49fbad8f206d488cc
Autor:
Natalie L. Goedeker, Sachi D. Dharia, Danielle A. Griffin, Jesantha Coy, Todd Truesdale, Rajan Parikh, Kasen Whitehouse, Sourav Santra, Damon R. Asher, Craig M. Zaidman
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Adeno-associated virus (AAV) vectors are a promising platform for in vivo transfer of transgenes designed to treat diseases. Pre-existing humoral immunity to these vectors can potentially impact the safety and efficacy of gene therapies.
Externí odkaz:
https://doaj.org/article/3188b9979c4a41868a6b7e86441ae1d1
Autor:
Jerry R. Mendell, Louise R. Rodino-Klapac, Navid Z. Khan, Damon R. Asher, Khampaseuth Thapa, Sachi D. Dharia, Rachael A. Potter
Publikováno v:
Expert Opinion on Biological Therapy. 20:263-274
Introduction: The development of adeno-associated virus (AAV) vectors as safe vehicles for in vivo delivery of therapeutic genes has been a major milestone in the advancement of gene therapy, enabl...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d71a96e5705c67b80da9572ffac0a14
https://doi.org/10.1080/14712598.2020.1725469
https://doi.org/10.1080/14712598.2020.1725469