Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Sacheen Kumar"'
Autor:
Kai Tai Derek Yeung, Joseph Doyle, Sacheen Kumar, Katharine Aitken, Diana Tait, David Cunningham, Long R. Jiao, Ricky Harminder Bhogal
Publikováno v:
Cancers, Vol 16, Iss 2, p 452 (2024)
Introduction: Neoadjuvant treatment (NAT) for borderline (BD) or locally advanced (LA) primary pancreatic cancer (PDAC) is now a widely adopted approach. We present a case series of patients who have achieved a complete pathological response of the p
Externí odkaz:
https://doaj.org/article/4c6cdbd8e4e44872b1e785313a8f8c3f
Autor:
Nikhil Manish Patel, Georgios Geropoulos, Pranav Harshad Patel, Ricky Harminder Bhogal, Kevin Joseph Harrington, Aran Singanayagam, Sacheen Kumar
Publikováno v:
Cancers, Vol 15, Iss 21, p 5252 (2023)
Survival in oesophago-gastric cancer (OGC) is poor due to early diagnostic challenges. Non-invasive risk stratification may identify susceptible patients with pre-malignant or benign disease. Following diagnostic confirmation with endoscopic biopsy,
Externí odkaz:
https://doaj.org/article/9b8cde5d6fc2474c8823758b9a731d61
Autor:
Rachna Gorbudhun, Pranav H. Patel, Eve Hopping, Joseph Doyle, Georgios Geropoulos, Vasileios K. Mavroeidis, Sacheen Kumar, Ricky H. Bhogal
Publikováno v:
Cancers, Vol 14, Iss 19, p 4678 (2022)
Background: Patients with borderline-resectable pancreatic ductal adenocarcinoma (BR-PDAC) have historically poor survival, even after curative pancreatic resection and adjuvant chemotherapy. Emerging evidence suggests that neoadjuvant chemoradiation
Externí odkaz:
https://doaj.org/article/b641798180534c7aaea5d1f865034ae2
Autor:
Irene Y. Chong, Naureen Starling, Alistair Rust, John Alexander, Lauren Aronson, Marta Llorca-Cardenosa, Ritika Chauhan, Asif Chaudry, Sacheen Kumar, Kerry Fenwick, Ioannis Assiotis, Nik Matthews, Ruwaida Begum, Andrew Wotherspoon, Monica Terlizzo, David Watkins, Ian Chau, Christopher J. Lord, Syed Haider, Sheela Rao, David Cunningham
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 2, p 215 (2021)
1. Background: The application of massively parallel sequencing has led to the identification of aberrant druggable pathways and somatic mutations within therapeutically relevant genes in gastro-oesophageal cancer. Given the widespread use of formali
Externí odkaz:
https://doaj.org/article/915bb413902f4856b83979729b3dfa2c
Autor:
Stephanos Pericleous, Sophie L. F. Doran, Andrew Wotherspoon, Monica Terlizzo, Angela Riddell, Gina Brown, Joshua Shur, Sue Chua, Nabil Hujairi, Nicos Middleton, David Cunningham, Sacheen Kumar, Ricky H. Bhogal
Publikováno v:
World Journal of Nuclear Medicine. 21:112-119
Background Gallbladder cancer has a poor prognosis and imaging can have variable diagnostic accuracy. We assessed the ability of preoperative 18F-fluorodeoxyglucose positron emission tomography computed tomography (18F-FDG-PET/CT) imaging to predict
Autor:
Charles Swanton, George B. Hanna, Daniel Hochhauser, Nik Matthews, Sharmin Begum, Jennifer Biggs, Benjamin Phillimore, Andrew Rowan, Stuart Horswell, Richard Mitter, Max Salm, Nima Abbassi-Ghadi, Sacheen Kumar, Nicholas McGranahan, Thomas B.K. Watkins, Nicolai J. Birkbak, Gareth A. Wilson, Nirupa Murugaesu
Detailed information of candidate driver mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05f8ab74581e5899ecc3038c9ab6a01
https://doi.org/10.1158/2159-8290.22531584
https://doi.org/10.1158/2159-8290.22531584
Autor:
Charles Swanton, George B. Hanna, Daniel Hochhauser, Nik Matthews, Sharmin Begum, Jennifer Biggs, Benjamin Phillimore, Andrew Rowan, Stuart Horswell, Richard Mitter, Max Salm, Nima Abbassi-Ghadi, Sacheen Kumar, Nicholas McGranahan, Thomas B.K. Watkins, Nicolai J. Birkbak, Gareth A. Wilson, Nirupa Murugaesu
Supplementary Materials and Methods Supplementary Table S1 - Sequencing coverage for tumor regions and germline samples Supplementary Table S2 - Clinical characteristics of patients with EAC Supplementary Table S4 - Annotation of chromosomal segments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21c40daeeff76e149cc62995df1e1c5
https://doi.org/10.1158/2159-8290.22531587
https://doi.org/10.1158/2159-8290.22531587
Gastroesophageal cancer has a rapidly increasing incidence worldwide and reliable biomarkers are urgently required to facilitate earlier diagnosis and improve survival. The aromatic amino acids tyrosine, phenylalanine, and tryptophan represent potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81671408eb060a550073aa9c80a87791
https://doi.org/10.1158/1055-9965.c.6516142
https://doi.org/10.1158/1055-9965.c.6516142
Autor:
George B. Hanna, Zoltan Takats, Robert Goldin, Kirill Veselkov, Emrys A. Jones, Hiromi Kudo, Nicole Strittmatter, Juzheng Huang, James S. McKenzie, Stefan Antonowicz, Sacheen Kumar, Ottmar Golf, Nima Abbassi-Ghadi
Histopathological assessment of lymph node metastases (LNM) depends on subjective analysis of cellular morphology with inter-/intraobserver variability. In this study, LNM from esophageal adenocarcinoma was objectively detected using desorption elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd724a188cfd44673bc3ac5f7ae473bc
https://doi.org/10.1158/0008-5472.c.6508539.v1
https://doi.org/10.1158/0008-5472.c.6508539.v1
Autor:
George B. Hanna, Zoltan Takats, Robert Goldin, Kirill Veselkov, Emrys A. Jones, Hiromi Kudo, Nicole Strittmatter, Juzheng Huang, James S. McKenzie, Stefan Antonowicz, Sacheen Kumar, Ottmar Golf, Nima Abbassi-Ghadi
Full methodological details of data analysis with respect to: tissue specific mass spectra extraction; data pre-processing (mass range selection, peak alignment, normalization, de-noising, data averaging); multivariate statistical models; glycerophos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2472ac3439ca3778064e55331893cdd6
https://doi.org/10.1158/0008-5472.22412856.v1
https://doi.org/10.1158/0008-5472.22412856.v1