Výsledky vyhledávání - "Sacha V Kepreotis"

Akademický článek

Inhibition of miR-25 ameliorates cardiac and skeletal muscle dysfunction in aged mdx/utrn haploinsufficient (+/−) mice

Autor: Sacha V. Kepreotis, Jae Gyun Oh, Mina Park, Jimeen Yoo, Cholong Lee, Mark Mercola, Roger J. Hajjar, Dongtak Jeong

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102174- (2024)

Dystrophic cardiomyopathy is a significant feature of Duchenne muscular dystrophy (DMD). Increased cardiomyocyte cytosolic calcium (Ca2+) and interstitial fibrosis are major pathophysiological hallmarks that ultimately result in cardiac dysfunction.

Externí odkaz: https://doaj.org/article/1cc3305bec1144ec93e2670c9a1ac745

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Akademický článek

Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF-β Signaling.

Autor: Jooyeon Kim, Jihwa Kim, Seung Hee Lee, Sacha V Kepreotis, Jimeen Yoo, Jang-Soo Chun, Roger J Hajjar, Dongtak Jeong, Woo Jin Park

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0166480 (2016)

Cytokine-like 1 (Cytl1) is a secreted protein that is involved in diverse biological processes. A comparative modeling study indicated that Cytl1 is structurally and functionally similar to monocyte chemoattractant protein 1 (MCP-1). As MCP-1 plays a

Externí odkaz: https://doaj.org/article/dadb5411b9fa4f74a7058c537b412006

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Multimodal Imaging and Endomyocardial Biopsy in the Assessment and Diagnosis of a Cardiac Melanoma

Autor: James Iliff, Mark Sader, Kyi P Thant, Abhisheik Prashar, Sacha V Kepreotis

Publikováno v: Circulation: Cardiovascular Imaging. 14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ad6bfd2b1cff74fcefe3277b1d7083
https://doi.org/10.1161/circimaging.121.012953

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miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure

Autor: Christine Wahlquist, Dongtak Jeong, Brian D. Brown, Mark Mercola, Roger J. Hajjar, Ahyoung Lee, Philyoung Lee, Jimeen Yoo, Sacha V. Kepreotis, Changwon Kho

MicroRNAs are promising therapeutic targets, because their inhibition has the potential to normalize gene expression in diseased states. Recently, our group found that miR-25 is a key SERCA2a regulating microRNA, and we showed that multiple injection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bae576006d8e703b6080b152e2ecdcb
https://europepmc.org/articles/PMC5910658/

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Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF-β Signaling

Autor: Dongtak Jeong, Sacha V. Kepreotis, Jang-Soo Chun, Woo Jin Park, Jimeen Yoo, Jooyeon Kim, Seung Hee Lee, Jihwa Kim, Roger J. Hajjar

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0166480 (2016)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420c1b7ce6933d498a5cb9115fe285a9
http://europepmc.org/articles/PMC5105950?pdf=render

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Akademický článek

Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF-β Signaling.

Autor: Kim, Jooyeon¹, Kim, Jihwa¹, Lee, Seung Hee¹, Kepreotis, Sacha V.², Yoo, Jimeen², Chun, Jang-Soo¹, Hajjar, Roger J.², Jeong, Dongtak² dongtak.jeong@mssm.edu, Park, Woo Jin¹ woojinpark@icloud.com

Publikováno v: PLoS ONE. 11/11/2016, Vol. 11 Issue 11, p1-15. 15p.

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Periodical

Icahn School of Medicine Researchers Illuminate Research in Gene Therapy [Inhibition of miR-25 ameliorates cardiac and skeletal muscle dysfunction in aged mdx/utrn haploinsufficient (+/-) mice].

Publikováno v: Gene Therapy Weekly; 8/30/2024, p379-379, 1p

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Akademický článek

Multimodal Imaging and Endomyocardial Biopsy in the Assessment and Diagnosis of a Cardiac Melanoma.

Autor: Thant, Kyi P., Iliff, James, Kepreotis, Sacha V., Prashar, Abhisheik, Sader, Mark

Publikováno v: Circulation: Cardiovascular Imaging; Sep2021, Vol. 14 Issue 9, p911-915, 5p

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