Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Sacha Lucchini"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117906 (2015)
Iron is essential for Escherichia coli growth and survival in the host and the external environment, but its availability is generally low due to the poor solubility of its ferric form in aqueous environments and the presence of iron-withholding prot
Externí odkaz:
https://doaj.org/article/2da6370f0a3143e0954ed7b2edef6a17
Autor:
Alexandra Sittka, Sacha Lucchini, Kai Papenfort, Cynthia M Sharma, Katarzyna Rolle, Tim T Binnewies, Jay C D Hinton, Jörg Vogel
Publikováno v:
PLoS Genetics, Vol 4, Iss 8, p e1000163 (2008)
Recent advances in high-throughput pyrosequencing (HTPS) technology now allow a thorough analysis of RNA bound to cellular proteins, and, therefore, of post-transcriptional regulons. We used HTPS to discover the Salmonella RNAs that are targeted by t
Externí odkaz:
https://doaj.org/article/7276c466503346a29788af0753bc0d8d
Autor:
Sacha Lucchini, Gary Rowley, Martin D Goldberg, Douglas Hurd, Marcus Harrison, Jay C. D Hinton
Publikováno v:
PLoS Pathogens, Vol 3, Iss 3 (2007)
Externí odkaz:
https://doaj.org/article/4fc44f07c2754c3082cb2cabc162cf2f
Autor:
Sacha Lucchini, Gary Rowley, Martin D Goldberg, Douglas Hurd, Marcus Harrison, Jay C D Hinton
Publikováno v:
PLoS Pathogens, Vol 2, Iss 8, p e81 (2006)
Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with the bacterial nucleoid. We used chromatin immunoprecipitation to determine the binding sites of H-NS and RNA polymerase on the Salmonella enterica serovar T
Externí odkaz:
https://doaj.org/article/0eba927b5def421395493737d56dfa8a
Publikováno v:
Environmental Microbiology. 15:487-501
Plants are increasingly considered as secondary reservoirs for commensal and pathogenic Escherichia coli strains, but the ecological and functional factors involved in this association are not clear. To address this question, we undertook a comparati
Autor:
József Baranyi, Matthew D. Rolfe, Roy P. Betts, Mark Alston, Michael W. Peck, Christopher J. Rice, Arthur Thompson, Michael F. Stringer, Carmen Pin, Jay C. D. Hinton, Sacha Lucchini, Andrew D. S. Cameron
Publikováno v:
Journal of Bacteriology. 194:686-701
Lag phase represents the earliest and most poorly understood stage of the bacterial growth cycle. We developed a reproducible experimental system and conducted functional genomic and physiological analyses of a 2-h lag phase in Salmonella enterica se
Publikováno v:
Molecular Microbiology. 74:139-158
Summary The small RNA, ArcZ (previously RyhA/SraH), was discovered in several genome-wide screens in Escherichia coli and Salmonella. Its high degree of genomic conservation, its frequent recovery by shotgun sequencing, and its association with the R
Publikováno v:
Nature Structural & Molecular Biology. 16:840-846
Bacterial small noncoding RNAs (sRNAs) generally recognize target mRNAs in the 5' region to prevent 30S ribosomes from initiating translation. It was thought that the mRNA coding sequence (CDS) was refractory to sRNA-mediated repression, because elon
Autor:
Isabelle Hautefort, Vittoria Danino, Mikael Rhen, Jay C. D. Hinton, Sacha Lucchini, Arthur Thompson, N Ahmad, Roy J. Bongaerts, M L Parker, S Eriksson-Ygberg
Publikováno v:
Cellular Microbiology
The biogenesis of the Salmonella-containing vacuole within mammalian cells has been intensively studied over recent years. However, the ability of Salmonella to sense and adapt to the intracellular environment of different types of host cells has rec
Publikováno v:
Molecular Microbiology
The bacterial envelope stress response (ESR) is triggered by the accumulation of misfolded outer membrane proteins (OMPs) upon envelope damage or excessive OMP synthesis, and is mediated by the alternative sigma factor, sigmaE. Activation of the GE p