Zobrazeno 1 - 10
of 464
pro vyhledávání: '"Sacha Gnjatic"'
Autor:
Jessica Young, Pawel Kalinski, Mateusz Opyrchal, Kathleen M Kokolus, Sacha Gnjatic, Jianming Wang, Shipra Gandhi, Kristopher Attwood, Tracey O’Connor, Kazuaki Takabe, Victoria Fitzpatrick, Eduardo Cortes Gomez, Stephen Edge, Janine Miller, Ronald T Slomba, Ellis G Levine, Sinem Ozbey, Giorgio Ioannou, Cayla Janes, Igor De Souza, Vladimir Roudko, Prasanna Kumar, Suresh Kalathil, Helen Cappuccino
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background Higher cytotoxic T lymphocyte (CTL) numbers in the tumor microenvironment (TME) predict pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) and positive long-term outcomes in triple-negative breast cancer (TNBC). pCR to NA
Externí odkaz:
https://doaj.org/article/d569717b5be14a588e378c08cde71fa3
Autor:
Hong Zhang, Riyue Bao, Song Liu, Mark Long, Sacha Gnjatic, Yi Xing, Elana J Fertig, Alan Hutson, Martin Morgan, Eytan Ruppin, Anant Madabhushi, Natalie Vokes, Daoud Meerzaman, Edgar Gonzalez-Kozlova, Vanessa D Jonsson, Eliezer M Van Allen, Spencer R Rosario, Jennifer Altreuter, Himangi Marathe, Jill S Barnholtz-Sloan, Lyndsay Harris, Qingrong Chen, James Dignam, Andrew J Gentles, Erika Kim, David Van Valen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Immuno-oncology has transformed the treatment of cancer, with several immunotherapies becoming the standard treatment across histologies. Despite these advancements, the majority of patients do not experience durable clinical benefits, highlighting t
Externí odkaz:
https://doaj.org/article/2a6c5ec863c6498aa1efe47fe6da43cb
Autor:
Seunghee Kim-Schulze, Sundar Jagannath, Sacha Gnjatic, Ajai Chari, Samir Parekh, Keren Osman, Selma Bekri, Hearn Jay Cho, David G Coffey, Adolfo Aleman, Simone Kats, Amishi Dhadwal, Donna Catamero
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Autologous stem cell transplantation (ASCT) after induction therapy improves disease-free survival for patients with multiple myeloma (MM). While the goal of ASCT is to render a minimal disease state, it is also associated with eradication
Externí odkaz:
https://doaj.org/article/4790a00a661e458ba2ebf32b8bdaa81f
Autor:
Carlo Bifulco, Holden T Maecker, Leslie Cope, Tricia Cottrell, Sacha Gnjatic, Michael T Lotze, Laura Chow, Joe Yeong Poh Shen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Abstract
Externí odkaz:
https://doaj.org/article/2d74683ef3124eb98ba5727bc8362385
Autor:
David G. Coffey, Francesco Maura, Edgar Gonzalez-Kozlova, J. Javier Diaz-Mejia, Ping Luo, Yong Zhang, Yuexin Xu, Edus H. Warren, Travis Dawson, Brian Lee, Hui Xie, Eric Smith, Amanda Ciardiello, Hearn J. Cho, Adeeb Rahman, Seunghee Kim-Schulze, Benjamin Diamond, Alexander Lesokhin, Dickran Kazandjian, Trevor J. Pugh, Damian J. Green, Sacha Gnjatic, Ola Landgren
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The role of the immune microenvironment in maintaining disease remission in patients with multiple myeloma (MM) is not well understood. In this study, we comprehensively profile the immune system in patients with newly diagnosed MM receiving
Externí odkaz:
https://doaj.org/article/f009262e72e74d7eb9e4d2fcf98a1f75
Autor:
Ishan Paranjpe, Pushkala Jayaraman, Chen-Yang Su, Sirui Zhou, Steven Chen, Ryan Thompson, Diane Marie Del Valle, Ephraim Kenigsberg, Shan Zhao, Suraj Jaladanki, Kumardeep Chaudhary, Steven Ascolillo, Akhil Vaid, Edgar Gonzalez-Kozlova, Justin Kauffman, Arvind Kumar, Manish Paranjpe, Ross O. Hagan, Samir Kamat, Faris F. Gulamali, Hui Xie, Joceyln Harris, Manishkumar Patel, Kimberly Argueta, Craig Batchelor, Kai Nie, Sergio Dellepiane, Leisha Scott, Matthew A. Levin, John Cijiang He, Mayte Suarez-Farinas, Steven G. Coca, Lili Chan, Evren U. Azeloglu, Eric Schadt, Noam Beckmann, Sacha Gnjatic, Miram Merad, Seunghee Kim-Schulze, Brent Richards, Benjamin S. Glicksberg, Alexander W. Charney, Girish N. Nadkarni
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Background Acute kidney injury (AKI) is a known complication of COVID-19 and is associated with an increased risk of in-hospital mortality. Unbiased proteomics using biological specimens can lead to improved risk stratification and discover
Externí odkaz:
https://doaj.org/article/a59378e85e3b46de854114917b9da8cd
Autor:
Chen-Yang Su, Sirui Zhou, Edgar Gonzalez-Kozlova, Guillaume Butler-Laporte, Elsa Brunet-Ratnasingham, Tomoko Nakanishi, Wonseok Jeon, David R. Morrison, Laetitia Laurent, Jonathan Afilalo, Marc Afilalo, Danielle Henry, Yiheng Chen, Julia Carrasco-Zanini, Yossi Farjoun, Maik Pietzner, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk, Meriem Bouab, Louis Petitjean, Charlotte Guzman, Xiaoqing Xue, Chris Tselios, Branka Vulesevic, Olumide Adeleye, Tala Abdullah, Noor Almamlouk, Yara Moussa, Chantal DeLuca, Naomi Duggan, Erwin Schurr, Nathalie Brassard, Madeleine Durand, Diane Marie Del Valle, Ryan Thompson, Mario A. Cedillo, Eric Schadt, Kai Nie, Nicole W. Simons, Konstantinos Mouskas, Nicolas Zaki, Manishkumar Patel, Hui Xie, Jocelyn Harris, Robert Marvin, Esther Cheng, Kevin Tuballes, Kimberly Argueta, Ieisha Scott, The Mount Sinai COVID-19 Biobank Team, Celia M. T. Greenwood, Clare Paterson, Michael A. Hinterberg, Claudia Langenberg, Vincenzo Forgetta, Joelle Pineau, Vincent Mooser, Thomas Marron, Noam D. Beckmann, Seunghee Kim-schulze, Alexander W. Charney, Sacha Gnjatic, Daniel E. Kaufmann, Miriam Merad, J. Brent Richards
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Predicting COVID-19 severity is difficult, and the biological pathways involved are not fully understood. To approach this problem, we measured 4701 circulating human protein abundances in two independent cohorts totaling 986 individuals. We
Externí odkaz:
https://doaj.org/article/01337ffce78741589c060c556f78383f
Autor:
Weiguang Mao, Clare M Miller, Venugopalan D Nair, Yongchao Ge, Mary Anne S Amper, Antonio Cappuccio, Mary‐Catherine George, Carl W Goforth, Kristy Guevara, Nada Marjanovic, German Nudelman, Hanna Pincas, Irene Ramos, Rachel S G Sealfon, Alessandra Soares‐Schanoski, Sindhu Vangeti, Mital Vasoya, Dawn L Weir, Elena Zaslavsky, Biobank Team, Vanessa Barcessat, Kevin Tuballes, Diane Marie Del Valle, Kai Nie, Hui Xie, Grace Chung, Manishkumar Patel, Jocelyn Harris, Kimberly Argueta, Jacques Fehr, Barr Gruberg, Nicholas Zaki, Seunghee Kim‐Schulze, Sacha Gnjatic, Miriam Merad, Andrew G Letizia, Olga G Troyanskaya, Stuart C Sealfon, Maria Chikina
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 5, Pp 1-16 (2023)
Abstract DNA methylation comprises a cumulative record of lifetime exposures superimposed on genetically determined markers. Little is known about methylation dynamics in humans following an acute perturbation, such as infection. We characterized the
Externí odkaz:
https://doaj.org/article/4218baf29182454bb07788f37ce0f8e4
Autor:
Padmanee Sharma, Seunghee Kim-Schulze, Justin David, John-William Sidhom, Sacha Gnjatic, Guray Akturk, Matthew Galsky, Saurabh Gupta, Jonathan Anker, Sudeh Izadmehr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a87f061d3d274b8da3f06b3089d13db9
Autor:
Padmanee Sharma, Seunghee Kim-Schulze, Justin David, John-William Sidhom, Sacha Gnjatic, Guray Akturk, Matthew Galsky, Saurabh Gupta, Jonathan Anker, Sudeh Izadmehr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3e6abb5815e349cb8de4229214235bd1