Zobrazeno 1 - 10
of 4 594
pro vyhledávání: '"Sacconi, A."'
Autor:
Federica Lo Sardo, Chiara Turco, Beatrice Messina, Andrea Sacconi, Francesca Romana Auciello, Claudio Pulito, Sabrina Strano, Sima Lev, Giovanni Blandino
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract The tumor suppressor PTEN (phosphatase and tensin homolog deleted in chromosome 10) is genetically deleted or downregulated in many cancer types. Loss of PTEN protein expression is frequently found in lung cancer while genetic alterations ar
Externí odkaz:
https://doaj.org/article/08430c12a9f548ffa6351d4edeaf6e1b
Autor:
Riccardo Sacconi, Mario Pezzella, Nicolo’ Ribarich, Matteo Menean, Andrea Servillo, Francesco Bandello, Giuseppe Querques
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract There is a lack of knowledge about the effect of flavanols-rich dark chocolate intake on the anatomy and functionality of retinal vessels. The aim of this study prospective, randomized, blind, crossover clinical trial (ClinicalTrials.gov Ide
Externí odkaz:
https://doaj.org/article/5b8de6881c4443c7b723d7b4ef265679
Autor:
Valeria Canu, Sebastiano Vaccarella, Andrea Sacconi, Claudio Pulito, Frauke Goeman, Matteo Pallocca, Daniela Rutigliano, Sima Lev, Sabrina Strano, Giovanni Blandino
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-15 (2024)
Abstract Triple negative breast cancer (TNBC) is an aggressive disease which currently has no effective therapeutic targets and prominent biomarkers. The Sperm Associated antigen 5 (SPAG5) is a mitotic spindle associated protein with oncogenic functi
Externí odkaz:
https://doaj.org/article/5435e8c8e2ce4120ac48f56e3d60ac59
Autor:
Valentina Piastra, Federica Ganci, Andrea Sacconi, Angelina Pranteda, Matteo Allegretti, Roberta Bernardini, Martina Serra, Barbara Lupo, Emanuela Dell’Aquila, Gianluigi Ferretti, Edoardo Pescarmona, Armando Bartolazzi, Giovanni Blandino, Livio Trusolino, Gianluca Bossi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Colorectal cancer (CRC) is the third most common type of cancer and the second leading cause of cancer-related deaths worldwide, with a survival rate near to 10% when diagnosed at an advanced stage. Hence, the identification of ne
Externí odkaz:
https://doaj.org/article/536b2932e0ac43d4922bd78ef035bbe1
Autor:
Andrea Servillo, Riccardo Sacconi, Gloria Oldoni, Eugenio Barlocci, Beatrice Tombolini, Marco Battista, Federico Fantaguzzi, Federico Rissotto, Cecilia Mularoni, Mariacristina Parravano, Ilaria Zucchiatti, Lea Querques, Francesco Bandello, Giuseppe Querques
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 8, Pp 2067-2082 (2024)
Abstract Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly, with dry AMD (d-AMD) leading to geographic atrophy (GA) and significant visual impairment. Multimodal imaging plays a crucial role in d-AMD diagnosis an
Externí odkaz:
https://doaj.org/article/ae03ea750de54489bb5dda9716234bd3
Autor:
Ali A. Habib, Sabrina Sacconi, Giovanni Antonini, Elena Cortés-Vicente, Julian Grosskreutz, Zabeen K. Mahuwala, Renato Mantegazza, Robert M. Pascuzzi, Kimiaki Utsugisawa, John Vissing, Tuan Vu, Heinz Wiendl, Marion Boehnlein, Bernhard Greve, Franz Woltering, Vera Bril
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Muscle-specific tyrosine kinase (MuSK) autoantibody-positive (Ab+) generalised myasthenia gravis (gMG) is a rare and frequently severe subtype of gMG. Objectives: To assess the efficacy and safety of rozanolixizumab in the subgroup of pat
Externí odkaz:
https://doaj.org/article/792b9660dfe54a3fafd21ea8a7d793f5
Autor:
Riccardo Sacconi, Andrea Servillo, Federico Rissotto, Leonardo Bottazzi, Eliana Costanzo, Maria Sole Polito, Beatrice Tombolini, Mariacristina Parravano, Francesco Bandello, Giuseppe Querques
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 5, Pp 1211-1222 (2024)
Abstract Introduction To characterize the response to antivascular endothelial growth factor (VEGF) treatment of macular neovascularization (MNV) secondary to age-related macular degeneration (AMD) with subclinical angioid streaks (AS) during a 2-yea
Externí odkaz:
https://doaj.org/article/26adc8c04b8e4c129cfd9123b0be03ab
Autor:
Claudio Pulito, Federica Mori, Andrea Sacconi, Frauke Goeman, Maria Ferraiuolo, Patrizia Pasanisi, Carlo Campagnoli, Franco Berrino, Maurizio Fanciulli, Rebecca J. Ford, Massimo Levrero, Natalia Pediconi, Ludovica Ciuffreda, Michele Milella, Gregory R. Steinberg, Mario Cioce, Paola Muti, Sabrina Strano, Giovanni Blandino
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-8 (2024)
Externí odkaz:
https://doaj.org/article/501e7d37afcc4aa583a480148d920162
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Age related macular degeneration (AMD) represents a leading cause of vision loss and it is expected to affect 288 million people by 2040. During the last decade, machine learning technologies have shown great potential to revolutionize clini
Externí odkaz:
https://doaj.org/article/a16e276e112643219eef3b5950986153
Autor:
Domenico Liguoro, Rachele Frigerio, Arianna Ortolano, Andrea Sacconi, Mario Acunzo, Giulia Romano, Giovanni Nigita, Barbara Bellei, Gabriele Madonna, Mariaelena Capone, Paolo Antonio Ascierto, Rita Mancini, Gennaro Ciliberto, Luigi Fattore
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-11 (2024)
Abstract Therapy of melanoma has improved dramatically over the last years thanks to the development of targeted therapies (MAPKi) and immunotherapies. However, drug resistance continues to limit the efficacy of these therapies. Our research group ha
Externí odkaz:
https://doaj.org/article/23532b4e96e84353911fe01ac65d5358