Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Sabyasachi Sanyal"'
Autor:
Harish Kumar, Suman Mazumder, Neeraj Sharma, Sayak Chakravarti, Mark D. Long, Nathalie Meurice, Joachim Petit, Song Liu, Marta Chesi, Sabyasachi Sanyal, A. Keith Stewart, Shaji Kumar, Leif Bergsagel, S. Vincent Rajkumar, Linda B. Baughn, Brian G. Van Ness, Amit Kumar Mitra
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multiple myeloma (MM) is an incurable plasma cell malignancy with dose-limiting toxicities and inter-individual variation in response/resistance to the standard-of-care/primary drugs, proteasome inhibitors (PIs), and immunomodulatory derivatives (IMi
Externí odkaz:
https://doaj.org/article/9603c59704384e5d91bde35c20185b77
Autor:
Harish Kumar, Sourav Chattopadhyay, Nabanita Das, Sonal Shree, Dinesh Patel, Jogeswar Mohapatra, Anagha Gurjar, Sapana Kushwaha, Abhishek Kumar Singh, Shikha Dubey, Kiran Lata, Rajesh Kushwaha, Riyazuddin Mohammed, Krishnarup Ghosh Dastidar, Namrata Yadav, Achchhe Lal Vishwakarma, Jiaur Rahaman Gayen, Sanghamitra Bandyopadhyay, Abhijit Chatterjee, Mukul Rameshchandra Jain, Anil Kumar Tripathi, Arun Kumar Trivedi, Naibedya Chattopadhyay, Ravishankar Ramachandran, Sabyasachi Sanyal
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
Leukemia stem cells contribute to drug-resistance and relapse in chronic myeloid leukemia (CML) and BCR-ABL1 inhibitor monotherapy fails to eliminate these cells, thereby necessitating alternate therapeutic strategies for patients CML. The peroxisome
Externí odkaz:
https://doaj.org/article/eec1ed33a21d4a788f8a7d4427a84e43
Autor:
Sharmistha Bhattacharyya, Subhashis Pal, Riyazuddin Mohamed, Priya Singh, Sourav Chattopadhyay, Shyamsundar Pal China, Konica Porwal, Sabyasachi Sanyal, Jiaur R. Gayen, Naibedya Chattopadhyay
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)
A combination of diosmin and hesperidin (9:1 ratio) is marketed as a dietary supplement/nutraceutical for cardiovascular health. We studied the skeletal effect of this combination (90% diosmin and 10% hesperidin, henceforth named as DH). We showed th
Externí odkaz:
https://doaj.org/article/3c4863ddd9a642d0bff05f80bac2a0ca
Autor:
Jyotsana Pandey, Kapil Dev, Sourav Chattopadhyay, Sleman Kadan, Tanuj Sharma, Rakesh Maurya, Sabyasachi Sanyal, Mohammad Imran Siddiqi, Hilal Zaid, Akhilesh Kumar Tamrakar
Publikováno v:
Molecules, Vol 26, Iss 11, p 3129 (2021)
Estrogenic molecules have been reported to regulate glucose homeostasis and may be beneficial for diabetes management. Here, we investigated the estrogenic effect of β-sitosterol-3-O-D-glucopyranoside (BSD), isolated from the fruits of Cupressus sem
Externí odkaz:
https://doaj.org/article/70a4318581c2496b9f1e27c35ba3be39
Autor:
Pooja Pal, Savita Lochab, Jitendra Kumar Kanaujiya, Isha Kapoor, Sabyasachi Sanyal, Gerhard Behre, Arun Kumar Trivedi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65330 (2013)
CCAAT/Enhancer Binding Protein Alpha (C/EBPα) is a key transcription factor involved in the adipocyte differentiation. Here for the first time we demonstrate that E6AP, an E3 ubiquitin ligase inhibits adipocyte differentiation in 3T3-L1 cells as rev
Externí odkaz:
https://doaj.org/article/b0980c0ce73b4c04b26b780d85c9aa5b
Autor:
Vandna Kukshal, Taran Khanam, Deepti Chopra, Nidhi Singh, Sabyasachi Sanyal, Ravishankar Ramachandran
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35702 (2012)
The sliding β-clamp, an important component of the DNA replication and repair machinery, is drawing increasing attention as a therapeutic target. We report the crystal structure of the M. tuberculosis β-clamp (Mtbβ-clamp) to 3.0 Å resolution. The
Externí odkaz:
https://doaj.org/article/8f920c67fb9b4df8901930b6b7595849
Autor:
Mukul Mishra, Anil Kumar Singh, Gatha Thacker, Vishal Upadhyay, Sabyasachi Sanyal, Arun Kumar Trivedi
Publikováno v:
Cell Biology International.
Autor:
Neha Rahuja, Harish Kumar, Hari Narayan Kushwaha, Bhawani Singh, A. K. Misra, Jyoti Gupta, Arvind K. Srivastava, Natasha Jaiswal, Ram Pratap, Anil Kumar Dwivedi, Dharmendra P Singh, Ishbal Ahmad, P. C. Verma, Rohit Srivastava, Anand P. Gupta, Akhilesh K. Tamrakar, Sabyasachi Sanyal, Sheo K. Singh, Varsha Gupta, Jiaur R. Gayen
Publikováno v:
Pharmacology. 107:54-68
Introduction: The present study deals with the synthesis of pregnane-oximino-amino-alkyl-ethers and their evaluation for antidiabetic and anti-dyslipidemic activities in validated animal and cell culture models. Methods: The effect on glucose toleran
Autor:
Harish Kumar, Andrew J. Paterson, Nick R Anderson, Shaowei Qiu, Sabyasachi Sanyal, Ravi Bhatia
Publikováno v:
Blood. 140:11533-11534
Autor:
Vishal Upadhyay, Anil Kumar Tripathi, Anil Kumar Singh, Madan Lal Brahma Bhatt, Arun Kumar Trivedi, Sabyasachi Sanyal, Gatha Thacker, Mukul Mishra, Akshay Sharma, Shailendra Prasad Verma
Publikováno v:
Molecular Cancer Research. 19:261-273
Glycogen synthase kinase 3β (GSK3β), an ubiquitously expressed serine/threonine kinase is reported to be overexpressed and hyperactivated in cancers including acute myeloid leukemia (AML) where it promotes self-renewal, growth, and survival of AML