Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Saburo Onishi"'
Autor:
Kazuaki Chayama, Saburo Onishi, Nobuyuki Enomoto, Michio Sata, Toshiji Saibara, Michio Imawari, Shuichi Kaneko, Kiwamu Okita
Publikováno v:
Hepatology Research. 44:410-419
Aim ME3738, a derivative of soyasapogenol B, enhances the anti-hepatitis C virus (HCV) effect of interferon in an in vitro replication system and an in vivo mouse model of HCV infection. ME3738 plus pegylated interferon (PEG IFN)-α-2a treatment for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e91abbaf4476bc2768ed465e16b37fb
https://doi.org/10.1111/hepr.12139
https://doi.org/10.1111/hepr.12139
Autor:
Masafumi Ono, Masaya Takahashi, Taketoshi Asanuma, Akira Hirose, Saburo Onishi, Shinji Iwasaki, Yasuko Nozaki, Kosuke Aritake, Nobuto Okamoto, Toshiji Saibara, Taketoshi Taniguchi, Jude A. Oben, Yoshihiro Urade, Mitsunari Ogasawara, Shuji Sakamoto
Publikováno v:
Liver International. 31:542-551
Background: The search for effective treatments of non-alcoholic steatohepatitis (NASH), now the most common chronic liver disease in affluent countries, is hindered by a lack of animal models having the range of anthropometric and pathophysiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907a98b7b75a3ac0c9d7c16320f41c23
https://doi.org/10.1111/j.1478-3231.2010.02443.x
https://doi.org/10.1111/j.1478-3231.2010.02443.x
Autor:
Masafumi Ono, Jude A. Oben, Mikinori Kuwabara, Yoshihiro Hayashi, Kei Kubota, Saburo Onishi, Akira Hirose, Taketoshi Asanuma, Toshiji Saibara, Hideaki Enzan, Osamu Inanami, Yasuhiro Ogawa
Publikováno v:
Gut. 59:258-266
BackgroundThe pathogenesis of non-alcoholic fatty liver disease (NAFLD) is incompletely understood. Kupffer cells (KCs), phagocytic liver-resident macrophages, provide a protective barrier against egress of endotoxin from the portal to the systemic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932c9042c9524207405c53ddd4d9cb62
https://doi.org/10.1136/gut.2009.176651
https://doi.org/10.1136/gut.2009.176651
Publikováno v:
Liver. 12:392-396
— Encephalopathy and severe coagulopathy in patients with acute hepatitis (AH) are good markers for the diagnosis of fulminant hepatitis (FH), which occurs in only about 1% of AH patients. However, even if patients show severe coagulopathy, it is q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13923bc226e68a9e1f9267fe57f53677
https://doi.org/10.1111/j.1600-0676.1992.tb00594.x
https://doi.org/10.1111/j.1600-0676.1992.tb00594.x
Autor:
Masako Miyazaki, Shinji Iwasaki, Takashi Maeda, Y Yamamoto, Takako Miyamoto, Hideaki Enzan, Saburo Onishi, Toshiji Saibara
Publikováno v:
Liver. 11:321-328
The source of activation of T lymphocytes in primary biliary cirrhosis (PBC) is undefined. Hence, T-cell-mediated reactivity against a biliary tract antigenic protein from human bile was studied. The bile protein was fractionated by 30-50% saturated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fde743f213e95325393269267f9235
https://doi.org/10.1111/j.1600-0676.1991.tb00537.x
https://doi.org/10.1111/j.1600-0676.1991.tb00537.x
Publikováno v:
Liver. 15:219-223
Hepatocyte regeneration is essential for recovery in acute hepatic failure, although it requires a large amount of energy. The ratio of acetoacetate to beta-hydroxybutyrate in arterial blood has been reported to reflect the cellular energy charge of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949f0e1796f40a07fa267ec44bee3e1d
https://doi.org/10.1111/j.1600-0676.1995.tb00674.x
https://doi.org/10.1111/j.1600-0676.1995.tb00674.x
Publikováno v:
Liver. 14:245-250
Liver-derived high density lymphocytes (Matsunaga cells) have been detected as members of resident T cells in the mouse liver. In this study, we assessed the immunological functions of liver-derived high density lymphocytes of BALB/c mice in comparis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba85105914c9aa4078620ad4186ba6b9
https://doi.org/10.1111/j.1600-0676.1994.tb00083.x
https://doi.org/10.1111/j.1600-0676.1994.tb00083.x
Publikováno v:
Digestive Diseases and Sciences. 54:2002-2008
Having noted a discrepancy between endoscopic and histopathological diagnoses in cases of minute adenomas of the colon, a prospective study was designed to clarify which is appropriate, magnifying chromoendoscopy or histopathology of a specimen obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682015bfc5cf5296ce0604f329b9cbdc
https://doi.org/10.1007/s10620-008-0573-7
https://doi.org/10.1007/s10620-008-0573-7
Autor:
Isao Nishimori, Claudiu T. Supuran, Tomoko Minakuchi, Andrea Scozzafava, Daniela Vullo, Saburo Onishi, Alessandro Cecchi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 24:70-76
The cytosolic human carbonic anhydrase (hCA, EC 4.2.1.1) isozyme III (hCA III) has been cloned and purified by the GST-fusion protein method. Recombinant pure hCA III had the following kinetic parameters for the CO(2) hydration reaction at 20 degrees
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf5278c423e1a7084dfda233a379c78
https://doi.org/10.1080/14756360801907143
https://doi.org/10.1080/14756360801907143
Publikováno v:
Journal of Gastroenterology. 43:597-602
The goal of this study was to clarify morphogenetic development in colorectal neoplasms with depressions by examining isolated crypts and their pit patterns.Twelve colorectal neoplasms with depressions were examined endoscopically, stereomicroscopica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e023ec7aae07afbb8e57553e4a1b02
https://doi.org/10.1007/s00535-008-2201-x
https://doi.org/10.1007/s00535-008-2201-x