Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Saburo Horiuchi"'
Publikováno v:
DNA repair. 43
The protein XRCC1 has no inherent enzymatic activity, and is believed to function in base excision repair as a dedicated scaffold component that coordinates other DNA repair factors. Repair foci clearly represent the recruitment and accumulation of D
Publikováno v:
Hepatology Research. 40:605-612
Aim The significance of cytokelatin-18 fragment cleaved by caspase-3 (CK-18-fr) and high mobility group box-1 (HMGB-1) were evaluated experimentally and clinically for the differential evaluation of hepatocyte apoptosis and necrosis in patients with
Autor:
Goro Tajima, Takashi Sawai, Sadafumi Ichinohe, Rie Kurose, Akira Kurose, Tadashi Shimamura, Saburo Horiuchi
Publikováno v:
International Journal of Rheumatic Diseases. 13:68-74
Aim: To investigate the possibility of chondrogenic differentiation and cartilage repair of synovial fluid cells of osteoarthritis (OA) knee. Methods: Synovial fluids from 26 patients with OA knee were aspirated from each knee joint and cultured in v
Autor:
Sanai Sato, Yosiko Kubota, Takako Takanami, Jian Xing Ma, Masatoshi Murata, Shinji Shimizu, Saburo Horiuchi, Wataru Habano
Publikováno v:
Current Eye Research. 31:171-180
The effects of diced small interfering RNAs (siRNAs) designed for vascular endothelial growth factor (VEGF) on the expression of VEGF in human retinal pigment epithelial cell line ARPE-19 cells in vitro and on corneal angiogenesis in vivo were examin
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 244:205-209
Corneal neovascularization (NV) plays an important role in the pathogenesis of corneal disorders. Recently, triamcinolone acetonide (TA) has been reported as a potential treatment for ocular angiogenesis. However, there are no reports on the inhibito
Autor:
Chizuko Isurugi, Saburo Horiuchi, Toru Sugiyama, Rie Oyama, Akimune Fukushima, Tadahiro Syoji, Hisao Kawahara
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 31:72-77
Aim: The aim of this study was to investigate heat-shock protein (Hsp)70 as a novel marker to evaluate the curative effects of treatment for preterm delivery high-risk patients and pre-eclampsia. Methods: After obtaining informed consent, serum sampl
Publikováno v:
Osteoarthritis and Cartilage. 13:154-161
Summary Objective The objective of this study was to clarify the effects of mechanical stress on chondrocytes cultured in a tube. Centrifugal pressure was applied to chondrocytes cultured in a tube for 28 days, and the effect of this stress was evalu
Autor:
Masatoshi Murata, Saburo Horiuchi
Publikováno v:
Ophthalmologica. 219:287-291
To understand the possible roles of the hyaluronan synthetase (HAS)/hyaluronan (HA)/CD44 signaling system in the posterior eye segment, we investigated the expression of rabbit HAS isoforms and CD44 mRNA by RT-PCR and the level of HA by using HA assa
Autor:
Saburo Horiuchi, Yoshiko Kubota
Publikováno v:
DNA Repair. 2:407-415
XRCC1 is known to be involved in base excision repair (BER)/single-strand break repair (SSBR) through interaction with other BER enzymes. Hypersensitivity of XRCC1-deficient cells against alkylating agents has been explained by loss of interaction wi
Autor:
Yongzhao Zhang, Tomoko Abe, Shigeo Yoshida, Saburo Horiuchi, Hidetoshi Aoki, Takako Takanami, Atsushi Higashitani, Hideyuki Takahashi
Publikováno v:
Journal of Radiation Research. 44:271-276
The effects of heavy ion particle irradiation on meiosis and reproductive development in the nematode Caenorhabditis elegans were studied. Meiotic pachytene nuclei are significantly resistant to particle irradiation by the heavy ions carbon and argon