Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Saburo, Ito"'
Autor:
Masahiro Torasawa, Hidehito Horinouchi, Shigehiro Yagishita, Hirofumi Utsumi, Keitaro Okuda, Daisuke Takekoshi, Saburo Ito, Hiroshi Wakui, Saori Murata, Sawako Kaku, Kae Okuma, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Tatsuya Yoshida, Yasushi Goto, Noboru Yamamoto, Jun Araya, Yuichiro Ohe, Yu Fujita
Publikováno v:
Thoracic Cancer, Vol 14, Iss 29, Pp 2909-2923 (2023)
Abstract Background Risk factors for predicting pneumonitis during durvalumab consolidation after chemoradiotherapy (CRT) in locally advanced non‐small cell lung cancer (LA‐NSCLC) are still lacking. Extracellular vesicles (EVs) play a crucial rol
Externí odkaz:
https://doaj.org/article/c26bd9ec8eaf4da5b06f23bbc99b43dc
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Recent advances in aging research have provided novel insights for the development of senotherapy, which utilizes cellular senescence as a therapeutic target. Cellular senescence is involved in the pathogenesis of various chronic diseases, including
Externí odkaz:
https://doaj.org/article/da0af1e1faaa494f95463543f9fbb771
Autor:
Masahiro Yoshida, Shunsuke Minagawa, Jun Araya, Taro Sakamoto, Hiromichi Hara, Kazuya Tsubouchi, Yusuke Hosaka, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Nahoko Sato, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirohumi Utsumi, Hiroshi Wakui, Takanori Numata, Yumi Kaneko, Shohei Mori, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Takeo Iwamoto, Hirotaka Imai, Kazuyoshi Kuwano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Altered iron homeostasis resulting in excessive oxidative stress has been implicated in smoke-induced lung diseases. Here the authors show that ferroptosis of lung epithelial cells, potentially resulting from excessive ferritinophagy, is involved in
Externí odkaz:
https://doaj.org/article/7f973dabdbee4e05bfa82fda5c334da7
Autor:
Kentaro Chida, Yumie Yamanaka, Akihito Sato, Saburo Ito, Naoki Takasaka, Takeo Ishikawa, Kazuyoshi Kuwano
Publikováno v:
Respiratory Medicine Case Reports, Vol 34, Iss , Pp 101510- (2021)
An 82-year-old Japanese man who previously had descending colon cancer and underwent partial resection showed a growing solitary pulmonary nodule, suspected as lung cancer, on follow-up computed tomography. Thoracoscopic partial lobectomy was therefo
Externí odkaz:
https://doaj.org/article/54b6245228d24843b8656d9e51efbe0f
Autor:
Hiromichi Hara, Keitaro Okuda, Jun Araya, Hirofumi Utsumi, Daisuke Takekoshi, Saburo Ito, Hiroshi Wakui, Shunsuke Minagawa, Takanori Numata, Kazuyoshi Kuwano
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261866 (2021)
ObjectivesRecently, incidence of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD) is increasing worldwide. We aimed to identify factors associated with severity of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD).MethodsAll patients d
Externí odkaz:
https://doaj.org/article/bcbcf424e87046ddbd4b10b74153fd55
Autor:
Takanori Numata, Katsutoshi Nakayama, Satoko Fujii, Yoko Yumino, Nayuta Saito, Masahiro Yoshida, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Yumi Kaneko, Kazuyoshi Kuwano
Publikováno v:
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to
Externí odkaz:
https://doaj.org/article/d3b90ddb33734d108fc053a57367d64e
Autor:
Yusuke Kurita, Jun Araya, Shunsuke Minagawa, Hiromichi Hara, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Kazuya Tsubouchi, Nahoko Sato, Masahiro Yoshida, Kenji Kobayashi, Saburo Ito, Yu Fujita, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Yutaka Yoshii, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Kazuyoshi Kuwano
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Pirfenidone (PFD) is an anti-fibrotic agent used to treat idiopathic pulmonary fibrosis (IPF), but its precise mechanism of action remains elusive. Accumulation of profibrotic myofibroblasts is a crucial process for fibrotic remod
Externí odkaz:
https://doaj.org/article/1146926490a44a5c8c9022cb1d7ba748
Autor:
Yu Fujita, Jun Araya, Saburo Ito, Kenji Kobayashi, Nobuyoshi Kosaka, Yusuke Yoshioka, Tsukasa Kadota, Hiromichi Hara, Kazuyoshi Kuwano, Takahiro Ochiya
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-12 (2015)
Extracellular vesicles (EVs), such as exosomes and microvesicles, encapsulate proteins and microRNAs (miRNAs) as new modulators of both intercellular crosstalk and disease pathogenesis. The composition of EVs is modified by various triggers to mainta
Externí odkaz:
https://doaj.org/article/5bd24b65c0ed4f6194fb91eb651b0ee8
Autor:
Tsukasa Kadota, Kenji Kobayashi, Yusuke Kurita, Saburo Ito, Katsutoshi Nakayama, Hiromichi Hara, Makoto Odaka, Takanori Numata, Hiroshi Wakui, Yumi Kaneko, Kazuya Tsubouchi, Shohei Mori, Akihiro Ichikawa, Makoto Yamashita, Yusuke Hosaka, Shunsuke Minagawa, Hirotaka Imai, Hisatoshi Asano, Kazuyoshi Kuwano, Nayuta Saito, Nahoko Sato, Masahiro Yoshida, Toshiaki Morikawa, Taro Sakamoto, Hirohumi Utsumi, Jun Araya, Takeo Iwamoto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Ferroptosis is a necrotic form of regulated cell death (RCD) mediated by phospholipid peroxidation in association with free iron-mediated Fenton reactions. Disrupted iron homeostasis resulting in excessive oxidative stress has been implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841b34bc8bc50cc9523737c8cc820ffe
https://doaj.org/article/7f973dabdbee4e05bfa82fda5c334da7
https://doaj.org/article/7f973dabdbee4e05bfa82fda5c334da7
Autor:
Hiromochi Hara, Mitsuo Hashimoto, Hironori Kawamoto, Nayuta Saito, Jun Araya, Shunsuke Minagawa, Tsukasa Kadota, Yu Fujita, Saburo Ito, Akihiko Ito, Akihiro Ichikawa, Daisuke Takekoshi, Naoaki Watanabe, Kazuyoshi Kuwano, Yusuke Hosaka, Shota Fujimoto
Publikováno v:
03.02 - Airway cell biology and immunopathology.
Introduction: Insufficient autophagic degradation has been implicated in accelerated cellular senescence during chronic obstructive pulmonary disease (COPD) pathogenesis. Cigarette smoke (CS)-induced functional deterioration of lysosomes may be assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1c1e0d5645c1d962573577d6ac9409
https://doi.org/10.1183/23120541.lsc-2021.69
https://doi.org/10.1183/23120541.lsc-2021.69