Výsledky vyhledávání - "Sabrina Yara"

Akademický článek

Iron-ascorbate-mediated lipid peroxidation causes epigenetic changes in the antioxidant defense in intestinal epithelial cells: impact on inflammation.

Autor: Sabrina Yara, Jean-Claude Lavoie, Jean-François Beaulieu, Edgard Delvin, Devendra Amre, Valerie Marcil, Ernest Seidman, Emile Levy

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63456 (2013)

INTRODUCTION: The gastrointestinal tract is frequently exposed to noxious stimuli that may cause oxidative stress, inflammation and injury. Intraluminal pro-oxidants from ingested nutrients especially iron salts and ascorbic acid frequently consumed

Externí odkaz: https://doaj.org/article/2722e8234b4a437aaa80f3df407b92ab

Zobrazit plný text záznamu

Molecular profiling of non-small-cell lung cancer patients with or without brain metastases included in the randomized SAFIR02-LUNG trial and association with intracranial outcome

Publikováno v: Lung Cancer
Lung Cancer, 2022, 169, pp.31-39. ⟨10.1016/j.lungcan.2022.05.004⟩

Lung cancer remains the most frequent cause of brain metastases (BMs) and is responsible for high morbidity and mortality. Intracranial response to systemic treatments is inconsistent due to several mechanisms: genomic heterogeneity, blood-tumor barr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0515e216ca1aadab56d391da8b8038
https://doi.org/10.1016/j.lungcan.2022.05.004

Zobrazit plný text záznamu

Abstract OT1-01-01: A randomised phase II trial of palbociclib and fulvestrant vs standard endocrine therapy in patients with ER positive HER2 negative breast cancer and ctDNA detected molecular relapse during adjuvant endocrine therapy (TRAK-ER)

Autor: Nicholas Turner, Edward R. Phillips, Catey Bunce, Marie Robert, Caroline Bailleux, Isaac Garcia-Murillas, Komel Khabra, Iain Macpherson, Ciara S. O’Brien, Alicia F. Okines, Carlo Palmieri, Peter Schmid, Claire Swift, Sabrina Yara, Simon Connolly, Jérôme Lemonnier, Dymphna Lee, Fabrice Andre

Publikováno v: Cancer Research. 83:OT1-01

Background: Most patients with early stage oestrogen receptor positive (ER+) and HER2 negative breast cancer will be cured of their cancer. However, up to 20% of patients may experience disease recurrence in the first 10 years. Molecular relapse of E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::854170add9a41805a641843136979b32
https://doi.org/10.1158/1538-7445.sabcs22-ot1-01-01

Zobrazit plný text záznamu

Brain 18 F-FDG PET Metabolic Abnormalities in Patients with Long-Lasting Macrophagic Myofascitis

Autor: François-Jérôme Authier, Mehdi Aoun Sebaiti, Anne-Ségolène Cottereau, Antoine Verger, Emmanuel Itti, Anne-Catherine Bachoud-Lévi, Sabrina Yara, Axel Van Der Gucht, Romain K. Gherardi, Julia Chalaye, Mukedaisi Abulizi, Eva Evangelista, Jessie Aouizerate, Eric Guedj

Publikováno v: Journal of Nuclear Medicine
Journal of Nuclear Medicine, Society of Nuclear Medicine, 2017, 58 (3), pp.492-498. ⟨10.2967/jnumed.114.151878⟩

The aim of this study was to characterize brain metabolic abnormalities in patients with macrophagic myofascitis (MMF) and the relationship with cognitive dysfunction through the use of PET with 18F-FDG. Methods:18F-FDG PET brain imaging and a compre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78331c5a3920f90f18308eddcbd649bb
https://hal.archives-ouvertes.fr/hal-02479857

Zobrazit plný text záznamu

PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells

Autor: Jean-François Beaulieu, Daniel Ménard, Schohraya Spahis, Sabrina Yara, Alain T. Sané, Ali Ben Djoudi Ouadda, Lea Emonnot, Emilie Grenier, Carole Garofalo, Emile Levy, Patrick Couture, Mounib Elchebly, Nabil G. Seidah

Publikováno v: Atherosclerosis. 227:297-306

Objectives The proprotein convertase subtillisin/kexin type 9 (PCSK9) regulates cholesterol metabolism via degradation of low-density lipoprotein receptor (LDLr). Although PCSK9 is abundantly expressed in the intestine, limited data are available on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581efad8801046a466e069c42ae8d653
https://doi.org/10.1016/j.atherosclerosis.2013.01.023

Zobrazit plný text záznamu

Total parenteral nutrition induces sustained hypomethylation of DNA in newborn guinea pigs

Autor: Emile Levy, Sabrina Yara, Wesam Elremaly, Jean-Claude Lavoie, Thérèse Rouleau

Publikováno v: Pediatric Research. 73:592-595

Neonatal total parenteral nutrition (TPN) is associated with animals with low glucose tolerance, body weight, and physical activity at adulthood. The early life origin of adult metabolic perturbations suggests a reprogramming of metabolism following

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f3cc136d71f12b4f2071275a77218c
https://doi.org/10.1038/pr.2013.35

Zobrazit plný text záznamu

Brain

Autor: Axel, Van Der Gucht, Mehdi, Aoun Sebaiti, Eric, Guedj, Jessie, Aouizerate, Sabrina, Yara, Romain K, Gherardi, Eva, Evangelista, Julia, Chalaye, Anne-Ségolène, Cottereau, Antoine, Verger, Anne-Catherine, Bachoud-Levi, Mukedaisi, Abulizi, Emmanuel, Itti, François-Jérôme, Authier

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(3)

The aim of this study was to characterize brain metabolic abnormalities in patients with macrophagic myofascitis (MMF) and the relationship with cognitive dysfunction through the use of PET with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfe1348e2a31f4a1a024176850db0ba6
https://pubmed.ncbi.nlm.nih.gov/28302762

Zobrazit plný text záznamu

Aluminum adjuvants of vaccines injected into the muscle: Normal fate, pathology and associated disease

Autor: François-Jérôme Authier, J. Cadusseau, Romain K. Gherardi, Jessie Aouizerate, Sabrina Yara

Publikováno v: Morphologie : bulletin de l'Association des anatomistes. 100(329)

Aluminum oxyhydroxide (Alhydrogel(®)) is a nano-crystalline compound forming aggregates that has been introduced in vaccine for its immunologic adjuvant effect in 1926. It is the most commonly used adjuvant in human and veterinary vaccines but mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90cb7bf13308231435a1c047aa3f41f
https://pubmed.ncbi.nlm.nih.gov/26948677

Zobrazit plný text záznamu

Oxidative stress and DNA methylation regulation in the metabolic syndrome

Autor: Jean-Claude Lavoie, Sabrina Yara, Emile Levy

Publikováno v: Epigenomics. 7(2)

DNA methylation is implicated in tissue-specific gene expression and genomic imprinting. It is modulated by environmental factors, especially nutrition. Modified DNA methylation patterns may contribute to health problems and susceptibility to complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46d372e1baa21c7d70a1a6633835499
https://pubmed.ncbi.nlm.nih.gov/25942536

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání