Výsledky vyhledávání - "Sabrina Yang"

Akademický článek

Scalability of Sartobind® Rapid A Membrane for High Productivity Monoclonal Antibody Capture

Autor: Sabrina Yang, Ryszard Braczkowski, Shih-Hsun Chen, Ricarda Busse, Yudhi Li, Louis Fabri, Innocent Berbelle Bekard

Publikováno v: Membranes, Vol 13, Iss 10, p 815 (2023)

Improved upstream titres in therapeutic monoclonal antibody (mAb) production have shifted capacity constraints to the downstream process. The consideration of membrane-based chromatographic devices as a debottlenecking option is gaining increasing at

Externí odkaz: https://doaj.org/article/4d8271e6100b44a5824ee398708c4979

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Akademický článek

High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Autor: Yu-Sang Sabrina Yang, Prabhani U. Atukorale, Kelly D. Moynihan, Ahmet Bekdemir, Kavya Rakhra, Li Tang, Francesco Stellacci, Darrell J. Irvine

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Assessing nanomaterials at the single cell level has proven to be complicated due to the limitations of existing techniques. Here, the authors utilised single-cell mass cytometry by time-of-flight as a label-free technique to analyse nanoparticle dis

Externí odkaz: https://doaj.org/article/6999926d3b0d49899d6ed81323f2cbf6

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Calcium-triggered fusion of lipid membranes is enabled by amphiphilic nanoparticles

Autor: Alfredo Alexander-Katz, Mukarram Tahir, Francesco Stellacci, Alisha N. Bhanji, Berta Tinao, Darrell J. Irvine, Laura R. Arriaga, Zekiye Pelin Guven, Jacob T. Martin, Yu-Sang Sabrina Yang, Ahmet Bekdemir

Publikováno v: Proc Natl Acad Sci U S A

Lipid membrane fusion is an essential process for a number of critical biological functions. The overall process is thermodynamically favorable but faces multiple kinetic barriers along the way. Inspired by nature’s engineered proteins such as SNAP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230e4477876b4a57f55b6fcf949c0c22
https://doi.org/10.1073/pnas.1902597117

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Akademický článek

Erratum: High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry

Autor: Yu-Sang Sabrina Yang, Prabhani U Atukorale, Kelly D. Moynihan, Ahmet Bekdemir, Kavya Rakhra, Li Tang, Francesco Stellacci, Darrell J Irvine

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)

Nature Communications 8 Article number: 14069 (2017); Published 17 January 2017; Updated 14 August 2017 In Fig. 4d of this Article, the schematic was incorrectly illustrated with one SIINFEKL peptide detached from a MUS/OT nanoparticle surface. The c

Externí odkaz: https://doaj.org/article/3257a761a2d24699b7c8e01d45ed502e

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Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation

Autor: Alessandra Cereghetti, Lorenzo Spagnuolo, Francesco Stellacci, Carole Bourquin, Ahmet Bekdemir, Yu-Sang Sabrina Yang, Marie Müller, Darrell J. Irvine, Inès Mottas

Publikováno v: Biomaterials, Vol. 190-191 (2019) pp. 111-120

Although immunotherapy shows great promise for the long-term control of cancer, many tumors still fail to respond to treatment. To improve the outcome, the delivery of immunostimulants to the lymph nodes draining the tumor, where the antitumor immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6fe3f7e2c291666e51ef04ab5b6334
http://doc.rero.ch/record/324118/files/mot_and.pdf

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Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

Autor: Yu-Sang Sabrina Yang, Tanmay Dichwalkar, Ahmet Bekdemir, Kelly D. Moynihan, Francesco Stellacci, Jessica R. Ingram, Nicki Watson, Heikyung Suh, Hidde L. Ploegh, Michelle M. Noh, Mariane B. Melo, Darrell J. Irvine

Publikováno v: Biomaterials science. 7(1)

We sought to develop a nanoparticle vehicle that could efficiently deliver small molecule drugs to target lymphocyte populations. The synthesized amphiphilic organic ligand-protected gold nanoparticles (amph-NPs) were capable of sequestering large pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf145b98a045422e793317bf39609b4
https://pubmed.ncbi.nlm.nih.gov/30444251

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Structure-Property Relationships of Amphiphilic Nanoparticles That Penetrate or Fuse Lipid Membranes

Autor: Francesco Stellacci, Zekiye Pelin Guven, Dong Soo Yun, Paulo Jacob Silva, Reid C. Van Lehn, Darrell J. Irvine, Randy P. Carney, Yu-Sang Sabrina Yang, Ahmet Bekdemir, Alfredo Alexander-Katz, Davide Demurtas, Prabhani U. Atukorale

Publikováno v: Bioconjugate chemistry. 29(4)

The development of synthetic nanomaterials that could embed within, penetrate, or induce fusion between membranes without permanent disruption would have great significance for biomedical applications. Here we describe structure-function relationship

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c824cc5fbbcc7ed4ac7f37b31979107c
https://pubmed.ncbi.nlm.nih.gov/29465986

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Vineland Adaptive Behavior Scales: II Profile of Young Children with Autism Spectrum Disorder

Autor: Linda Gilmore, Sabrina Yang, Jessica Paynter

Publikováno v: Journal of Autism and Developmental Disorders. 46:64-73

Adaptive behaviour is a crucial area of assessment for individuals with Autism Spectrum Disorder (ASD). This study examined the adaptive behaviour profile of 77 young children with ASD using the Vineland-II, and analysed factors associated with adapt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd7b5bf0296d7c29ee79d779f65340f
https://doi.org/10.1007/s10803-015-2543-1

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