Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sabrina Vogel"'
Autor:
Johanna Heider, Emilio Pardo González, Sophia-Marie Hartmann, Nirmal Kannaiyan, Sabrina Vogel, Richard Wüst, Andreas J. Fallgatter, Moritz J. Rossner, Udo Kraushaar, Hansjürgen Volkmer
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106678- (2024)
Schizophrenia (SCZ) is a psychiatric disorder with a strong genetic determinant. A major hypothesis to explain disease aetiology comprises synaptic dysfunction associated with excitatory-inhibitory imbalance of synaptic transmission, ultimately contr
Externí odkaz:
https://doaj.org/article/5d3a1f85a2f0489fb106cbce8f0988f6
Autor:
Johanna Heider, Aaron Stahl, Denise Sperlich, Sophia-Marie Hartmann, Sabrina Vogel, Ricarda Breitmeyer, Markus Templin, Hansjürgen Volkmer
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract Background Mutations in the gene DISC1 are associated with increased risk for schizophrenia, bipolar disorder and major depression. The study of mutated DISC1 represents a well-known and comprehensively characterized approach to understand n
Externí odkaz:
https://doaj.org/article/1113a8edc4e34a2a87fef4ae3a9fb152
Autor:
Xiaoxia Liu, Guoze Feng, Sabrina Vogel Marler, Menno V Huisman, Gregory Y. H. Lip, Changsheng Ma
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Stroke prevention with oral anticoagulant (OAC) therapy, including non-vitamin K antagonist oral anticoagulants (NOACs), is recommended in patients with atrial fibrillation (AF). This analysis describes the antithrombotic prescrip
Externí odkaz:
https://doaj.org/article/eaf4277d9aee47a0b19d92d2ded7ee3b
Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction
Autor:
Ricarda Breitmeyer, Sabrina Vogel, Johanna Heider, Sophia-Marie Hartmann, Richard Wüst, Anna-Lena Keller, Anna Binner, Julia C. Fitzgerald, Andreas J. Fallgatter, Hansjürgen Volkmer
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia spectrum (SCZ), which is potentially related to activated microglia and increased inflammation. Induced pluripotent stem c
Externí odkaz:
https://doaj.org/article/1df2e8cc9f874ebdb70e23e08beb33b9
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102925- (2022)
DISC1 is a scaffold protein involved in key developmental processes such as neuronal migration, differentiation and neurogenesis. Genetic variants of the DISC1 gene have been linked to neuropsychiatric disorders like schizophrenia, bipolar disorder a
Externí odkaz:
https://doaj.org/article/331dc85b5c6d4cc08a55349c3814dfd0
Autor:
Nicole Rothe, Sabrina Vogel, Kristin Schmelzer, Clemens Kirschbaum, Marlene Penz, Magdalena Katharina Wekenborg, Wei Gao, Andreas Walther
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 7, Iss , Pp 100051- (2021)
For poor sleep quality (SQ) as well as major depressive disorder (MDD) and burnout, a dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been identified. Although poor SQ is often reported as an early symptom of MDD or burnout, it is
Externí odkaz:
https://doaj.org/article/4c3105a1e000488bbc34f2155db50d0e
Autor:
Anna-Lena Keller, Anna Binner, Ricarda Breitmeyer, Sabrina Vogel, Nicole Anderle, Ulrich Rothbauer, Katja Schenke-Layland, Christian Schmees
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102427- (2021)
Peripheral-blood derived CD34+ hematopoietic stem and progenitor cells were isolated from a 49-year old male donor and were successfully reprogrammed into human induced pluripotent stem cells (hiPSCs) using integration-free episomal vectors. The hiPS
Externí odkaz:
https://doaj.org/article/46e3f17e22134f53a41e27fbaf9066cc
Autor:
Ricarda Stock, Sabrina Vogel, Ulrike A. Mau-Holzmann, Martin Kriebel, Richard Wüst, Andreas J. Fallgatter, Hansjürgen Volkmer
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101961- (2020)
Fibroblasts were isolated from skin biopsies of four patients diagnosed with schizophrenia and from one healthy control. Patient fibroblasts were transfected with five episomal, non-integrative reprogramming vectors to generate human induced pluripot
Externí odkaz:
https://doaj.org/article/3db6d0b61eea4231acce777425b5fdee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10254 (2021)
Neuropsychiatric disorders such as schizophrenia or autism spectrum disorder represent a leading and growing burden on worldwide mental health. Fundamental lack in understanding the underlying pathobiology compromises efficient drug development despi
Externí odkaz:
https://doaj.org/article/02a76f3b9b3b484f85bead974eb8b7b2
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